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The emergence of SARS-CoV-2 variants of concern endangers the long-term control of COVID-19, especially in countries with limited genomic surveillance. In this work, we explored genomic drivers of contagion in Chile. We sequenced 3443…

The Coronavirus Disease 2019 or the COVID-19 pandemic has swept almost all parts of the world since the first case was found in Wuhan, China, in December 2019. With the increasing number of COVID-19 cases in the world, SARS-CoV-2 has…

Computational Engineering, Finance, and Science · Computer Science 2023-01-31 Akhmad Dimitri Baihaqi , Novanto Yudistira , Edy Santoso

We compute the allele frequencies of the alpha (B.1.1.7), beta (B.1.351) and delta (B.167.2) variants of SARS-CoV-2 from almost two million genome sequences on the GISAID repository. We find that the frequencies of a majority of the…

Populations and Evolution · Quantitative Biology 2021-09-08 Hong-Li Zeng , Yue Liu , Vito Dichio , Kaisa Thorell , Rickard Nordén , Erik Aurell

COVID-19 pandemic has reshaped our world in a timescale much shorter than what we can understand. Particularities of SARS-CoV-2, such as its persistence in surfaces and the lack of a curative treatment or vaccine against COVID-19, have…

In this work, we developed a deep learning model-based approach to forecast the spreading trend of SARS-CoV-2 in the United States. We implemented the designed model using the United States to confirm cases and state demographic data and…

Computers and Society · Computer Science 2020-08-14 Tong Yang , Long Sha , Justin Li , Pengyu Hong

A plethora of prediction models of SARS-CoV-2 pandemic were proposed in the past. Prediction performances not only depend on the structure and features of the model, but also on its parametrization. Official databases are often biased due…

Populations and Evolution · Quantitative Biology 2021-09-27 Yuri Kheifetz , Holger Kirsten , Markus Scholz

Until now, Coronavirus SARS-CoV-2 has caused more than 850,000 deaths and infected more than 27 million individuals in over 120 countries. Besides principal polymerase chain reaction (PCR) tests, automatically identifying positive samples…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Duy M. H. Nguyen , Duy M. Nguyen , Huong Vu , Binh T. Nguyen , Fabrizio Nunnari , Daniel Sonntag

The seasonal human influenza virus undergoes rapid evolution, leading to significant changes in circulating viral strains from year to year. These changes are typically driven by adaptive mutations, particularly in the antigenic epitopes,…

Populations and Evolution · Quantitative Biology 2024-11-28 Matthijs Meijers , Denis Ruchnewitz , Jan Eberhardt , Malancha Karmakar , Marta Łuksza , Michael Lässig

A molecular and cellular understanding of how SARS-CoV-2 variably infects and causes severe COVID-19 remains a bottleneck in developing interventions to end the pandemic. We sought to use deep learning to study the biology of SARS-CoV-2…

Machine Learning · Computer Science 2020-12-16 Arijit Sehanobish , Neal G. Ravindra , David van Dijk

Countries are recording health information on the global spread of COVID-19 using different methods, sometimes changing the rules after a few days. They are all publishing the number of new individuals infected, cured and dead, along with…

Populations and Evolution · Quantitative Biology 2020-12-15 J. M. Calabuig , L. M. García-Raffi , A. García-Valiente , E. A. Sánchez-Pérez

Structure-based Deep Fusion models were recently shown to outperform several physics- and machine learning-based protein-ligand binding affinity prediction methods. As part of a multi-institutional COVID-19 pandemic response, over 500…

Prominently accountable for the upsurge of COVID-19 cases as the world attempts to recover from the previous two waves, Omicron has further threatened the conventional therapeutic approaches. Omicron is the fifth variant of concern (VOC),…

Other Quantitative Biology · Quantitative Biology 2022-05-11 Md Sorwer Alam Parvez , Manash Kumar Saha , Md. Ibrahim , Yusha Araf , Md. Taufiqul Islam , Gen Ohtsuki , Mohammad Jakir Hosen

The understanding of the mechanisms of SARS-CoV-2 evolution and transmission is one of the greatest challenges of our time. By integrating artificial intelligence (AI), viral genomes isolated from patients, tens of thousands of mutational…

Quantitative Methods · Quantitative Biology 2022-09-08 Guo-Wei Wei

Drug repurposing can accelerate the identification of effective compounds for clinical use against SARS-CoV-2, with the advantage of pre-existing clinical safety data and an established supply chain. RNA viruses such as SARS-CoV-2…

The acute phase of the Covid-19 pandemic has made apparent the need for decision support based upon accurate epidemic modeling. This process is substantially hampered by under-reporting of cases and related data incompleteness issues. In…

Applications · Statistics 2026-03-10 Anastasios Apsemidis , Nikolaos Demiris

The COVID-19 outbreak resulted in multiple waves of infections that have been associated with different SARS-CoV-2 variants. Studies have reported differential impact of the variants on respiratory health of patients. We explore whether…

The SARS-CoV-2 pandemic has emphasised the importance of developing a universal vaccine that can protect against current and future variants of the virus. The present study proposes a novel conditional protein Language Model architecture,…

During 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission has been increasing amongst the world's population at an alarming rate. Reducing the spread of SARS-CoV-2 and other diseases that are spread in…

Social and Information Networks · Computer Science 2022-03-22 Patrick Urrutia , David Wren , Chrysafis Vogiatzis , Ruriko Yoshida

The SARS-CoV-2 virus and COVID-19 disease have posed unprecedented and overwhelming demand, challenges and opportunities to domain, model and data driven modeling. This paper provides a comprehensive review of the challenges, tasks,…

Computers and Society · Computer Science 2021-08-05 Longbing Cao , Qing Liu

The number of unique terms in the scientific literature used to refer to either SARS-CoV-2 or COVID-19 is remarkably large and has continued to increase rapidly despite well-established standardized terms. This high degree of term variation…

Digital Libraries · Computer Science 2020-10-29 Robert Leaman , Zhiyong Lu