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Despite the progress in medical care, combined population-wide interventions (such as physical distancing, testing and contact tracing) are still crucial to manage the SARS-CoV-2 pandemic, aggravated by the emergence of new highly…

The SARS-CoV-2 pandemic has added new urgency to the study of viral mechanisms of infection. But while vaccines offer a measure of protection against this specific outbreak, a new era of pandemics has been predicted. In addition to this,…

Biological Physics · Physics 2022-10-25 Betony Adams , Ilya Sinayskiy , Rienk van Grondelle , Francesco Petruccione

The discovery of SARS-CoV-2, the responsible virus for the Covid-19 epidemic, has sparked a global health concern with many countries affected. Developing models that can interpret the epidemic and give common trend parameters are useful…

Populations and Evolution · Quantitative Biology 2021-09-21 Milad Radiom , Jean-Franccois Berret

The ongoing global pandemic of infection disease COVID-19 caused by the 2019 novel coronavirus (SARS-COV-2, formerly 2019-nCoV) presents critical threats to public health and the economy since it was identified in China, December 2019. The…

Genomics · Quantitative Biology 2020-06-02 Changchuan Yin

Over the past 150 years, vaccines have revolutionized the relationship between people and disease. During the COVID-19 pandemic, technologies such as mRNA vaccines have received attention due to their novelty and successes. However, more…

The mechanism of SARS-CoV-2 evolution and transmission is elusive and its understanding, a prerequisite to forecast emerging variants, is of paramount importance. SARS-CoV-2 evolution is driven by the mechanisms at molecular and organism…

Populations and Evolution · Quantitative Biology 2021-09-20 Jiahui Chen , Rui Wang , Guo-Wei Wei

SARS-CoV2, which causes coronavirus disease (COVID-19) is continuing to spread globally and has become a pandemic. People have lost their lives due to the virus and the lack of counter measures in place. Given the increasing caseload and…

More infectious virus variants can arise from rapid mutations in their proteins, creating new infection waves. These variants can evade one's immune system and infect vaccinated individuals, lowering vaccine efficacy. Hence, to improve…

Machine Learning · Computer Science 2022-05-31 Glenda Tan Hui En , Koay Tze Erhn , Shen Bingquan

The deadly coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has gone out of control globally. Despite much effort by scientists, medical experts, and society in general, the…

Biomolecules · Quantitative Biology 2021-02-02 Kaifu Gao , Rui Wang , Jiahui Chen , Limei Cheng , Jaclyn Frishcosy , Yuta Huzumi , Yuchi Qiu , Tom Schluckbier , Guo-Wei Wei

The COVID-19 pandemic has presented many challenges that have spurred biotechnological research to address specific problems. Diagnostics is one area where biotechnology has been critical. Diagnostic tests play a vital role in managing a…

We provide a predictive analysis of the spread of COVID-19, also known as SARS-CoV-2, using the dataset made publicly available online by the Johns Hopkins University. Our main objective is to provide predictions of the number of infected…

Machine Learning · Computer Science 2020-05-26 Alireza M. Javid , Xinyue Liang , Arun Venkitaraman , Saikat Chatterjee

With the ongoing global pandemic of coronavirus disease 2019 (COVID-19), there is an increasing quest for more accessible, easy-to-use, rapid, inexpensive, and high accuracy diagnostic tools. Traditional disease diagnostic methods such as…

Increasing number in global COVID-19 cases demands for mathematical model to analyze the interaction between the virus dynamics and the response of innate and adaptive immunity. Here, based on the assumption of a weak and delayed response…

Populations and Evolution · Quantitative Biology 2021-01-13 Zhengqing Zhou , Zhiheng Zhao , Shuyu Shi , Jianghua Wu , Dianjie Li , Jianwei Li , Jingpeng Zhang , Ke Gui , Yu Zhang , Heng Mei , Yu Hu , Qi Ouyang , Fangting Li

COVID-19 is an infection caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2), which has caused a global outbreak. Current research efforts are focused on the understanding of the molecular mechanisms involved in…

In 2019, the world faced a new challenge: a COVID-19 disease caused by the novel coronavirus, SARS-CoV-2. The virus rapidly spread across the globe, leading to a high rate of mortality, which prompted health organizations to take measures…

Image and Video Processing · Electrical Eng. & Systems 2024-08-08 Kavian Khanjani , Seyed Rasoul Hosseini , Hamid Taheri , Shahrzad Shashaani , Mohammad Teshnehlab

SARS-CoV-2 coronavirus infection is mediated by the binding of its spike protein to the angiotensin-converting enzyme 2 (ACE2), which plays a pivotal role in the renin-angiotensin system (RAS). The study of RAS dysregulation due to…

Molecular Networks · Quantitative Biology 2020-08-04 Fabrizio Pucci , Philippe Bogaerts , Marianne Rooman

Interactions between SARS-CoV-2 and human proteins (SARS-CoV-2 PPIs) cause information transfer through biochemical pathways that contribute to the immunopathology of COVID-19. Here, we present a communication network model of the immune…

Molecular Networks · Quantitative Biology 2022-08-15 Swarnavo Sarkar

COVID-19 has created a global pandemic with high morbidity and mortality in 2020. Novel coronavirus (nCoV), also known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2), is responsible for this deadly disease. International…

Molecular Networks · Quantitative Biology 2020-05-11 Sovan Saha , Anup Kumar Halder , Soumyendu Sekhar Bandyopadhyay , Piyali Chatterjee , Mita Nasipuri , Subhadip Basu

In light of the continuous transmission and evolution of SARS-CoV-2 coupled with a significant decline in clinical testing, there is a pressing need for scalable, cost-effective, long-term, passive surveillance tools to effectively monitor…

The novel coronavirus (SARS-CoV-2) has led to a pandemic. The current testing regime based on Reverse Transcription-Polymerase Chain Reaction for SARS-CoV-2 has been unable to keep up with testing demands, and also suffers from a relatively…

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