Related papers: Dosimetric Comparison of Passive Scattering and Ac…
Introduction: Real-time dosimetry of surface doses in electron beams has not been widely established yet. Plastic scintillation detectors (PSD) promise high spatial resolution and real-time dosimetry with minimum perturbation of the…
Proton minibeam (pMB) radiotherapy, delivers highly heterogeneous dose distributions alternating high-dose peaks and low-dose valleys. This aims to widen the therapeutic window by improving normal tissue sparing while maintaining the same…
Purpose: The presence of respiratory motion during radiation treatment leads to degradation of the expected dose distribution, both for target coverage and healthy-tissue sparing, particularly for techniques like pencil-beam scanning proton…
The purpose of this study was to investigate the feasibility of extracting proton beams with two distinct energies within a single synchrotron cycle. The energy difference between the beams should be sufficient to use one beam as a range…
Carbon ion therapy have the ability to overcome the limitation of convertional radiotherapy due to its most energy deposition in selective depth, usually called Bragg peak, which results in increased biological effectiness. During carbon…
Treatment planning system calculations in inhomogeneous regions may present significant inaccuracies due to loss of electronic equilibrium. In this study, three different dose calculation algorithms, pencil beam, collapsed cone, and…
Adaptive Radiation Therapy (ART) was developed based on Image-guided Radiation Therapy (IGRT) and it is the trend of photon radiation therapy. To get a better use of Cone Beam CT (CBCT) images for ART, the CBCT system model was established…
Physical and biological range uncertainties limit the clinical potential of Proton Beam Therapy (PBT). In this proceedings, we report on two research projects, which we are conducting in parallel and which both tackle the problem of range…
Radiation dose is an important performance indicator of a dedicated breast CT (DBCT). In this paper, the method of putting thermoluminescent dosimeters (TLD) into a breast shaped PMMA phantom to study the dose distribution in breasts was…
Monte Carlo (MC) is generally considered as the most accurate dose calculation tool for particle therapy. However, a proper description of the beam particles kinematics is a necessary input for a realistic simulation. Such a description can…
The purpose of this work is to develop viable procedures for verifying the applicability of personalized dosimetry in computed tomography (CT) using Monte Carlo-based simulations. Mobile equipment together with customized software was…
A set of nozzle equipment for proton therapy is now being developed at China Institute of Atomic Energy. To facilitate the off-line commissioning of the whole equipment, a set of ionization chamber signal generation system, the test…
Predictive dosimetry is central to enabling personalized radiopharmaceutical therapy (RPT), particularly in prostate specific membrane antigen (PSMA) targeted theranostics. In this work, we develop a three layer computational framework that…
Objective: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring. Approach: The Monte Carlo simulation studies with GATE and…
Dose verification based on proton-induced positron emitters is a promising quality assurance tool and may leverage the strength of artificial intelligence. To move a step closer towards practical application, the sensitivity analysis of two…
Depth distributions of positron-emitting nuclei in PMMA phantoms are calculated within a Monte Carlo model for Heavy-Ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.0). The calculated total production rates of $^{11}$C, $^{10}$C…
Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…
We have determined the depth-dose curve, the penetration range, and the water equivalent ratio (WER), for proton beams of clinical energies in cortical bone, by means of a detailed and accurate simulation that combines molecular dynamics…
This study introduces the HYPERSCINT research platform, the first commercially available scintillation dosimetry platform capable of multi-point dosimetry through the hyperspectral approach. Optic and dosimetric performances of the system…
Verification of patient specific proton stopping powers obtained in the patient treatment position can be used to reduce the distal margins needed in particle beam planning. Proton radiography can be used as a pre-treatment instrument to…