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We present SAM4EM, a novel approach for 3D segmentation of complex neural structures in electron microscopy (EM) data by leveraging the Segment Anything Model (SAM) alongside advanced fine-tuning strategies. Our contributions include the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Uzair Shah , Marco Agus , Daniya Boges , Vanessa Chiappini , Mahmood Alzubaidi , Jens Schneider , Markus Hadwiger , Pierre J. Magistretti , Mowafa Househ , Corrado Calı

Extracting high-fidelity 2D contours from Scanning Electron Microscope (SEM) images is critical for calibrating Optical Proximity Correction (OPC) models. While foundation models like Segment Anything 2 (SAM2) are promising, adapting them…

Hardware Architecture · Computer Science 2026-04-21 Da Chen , Guangyu Hu , Kaihong Xu , Kaichao Liang , Songjiang Li , Wei Yang , XiangYu Wen , Mingxuan Yuan

The development of personalized human head models from medical images has become an important topic in the electromagnetic dosimetry field, including the optimization of electrostimulation, safety assessments, etc. Human head models are…

Image and Video Processing · Electrical Eng. & Systems 2020-02-24 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

Three-dimensional electron microscopy (3DEM) is an essential technique to investigate volumetric tissue ultra-structure. Due to technical limitations and high imaging costs, samples are often imaged anisotropically, where resolution in the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Mohammad Khateri , Morteza Ghahremani , Alejandra Sierra , Jussi Tohka

Reconstructing perceived images from human brain activity monitored by functional magnetic resonance imaging (fMRI) is hard, especially for natural images. Existing methods often result in blurry and unintelligible reconstructions with low…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 Mali Halac , Murat Isik , Hasan Ayaz , Anup Das

Semiconductor imaging and analysis are critical yet understudied in deep learning, limiting our ability for precise control and optimization in semiconductor manufacturing. We introduce a small-scale multimodal framework for analyzing…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Sakhinana Sagar Srinivas , Chidaksh Ravuru , Geethan Sannidhi , Venkataramana Runkana

Deep convolutional neural networks (DCNNs) have demonstrated excellent performance in object recognition and have been found to share some similarities with brain visual processing. However, the substantial gap between DCNNs and human…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Zitong Lu , Yile Wang

Accurate segmentation of neural structures in Electron Microscopy (EM) images is paramount for neuroscience. However, this task is challenged by intricate morphologies, low signal-to-noise ratios, and scarce annotations, limiting the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zhenghua Li , Hang Chen , Zihao Sun , Kai Li , Xiaolin Hu

In the past decade, deep conditional generative models have revolutionized the generation of realistic images, extending their application from entertainment to scientific domains. Single-particle cryo-electron microscopy (cryo-EM) is…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Jiakai Zhang , Qihe Chen , Yan Zeng , Wenyuan Gao , Xuming He , Zhijie Liu , Jingyi Yu

The scanning electron microscopy (SEM) is probably one the most fascinating examination approach that has been used since more than two decades to detailed inspection of micro scale objects. Most of the scanning electron microscopes could…

Computer Vision and Pattern Recognition · Computer Science 2016-02-18 Wichai Shanklin

Electron microscopy has shown to be a very powerful tool to map the chemical nature of samples at various scales down to atomic resolution. However, many samples can not be analyzed with an acceptable signal-to-noise ratio because of the…

Image and Video Processing · Electrical Eng. & Systems 2018-02-28 Étienne Monier , Thomas Oberlin , Nathalie Brun , Marcel Tencé , Marta de Frutos , Nicolas Dobigeon

Segmentation of nanoscale electron microscopy (EM) images is crucial but still challenging in connectomics research. One reason for this is that none of the existing segmentation methods are error-free, so they require proofreading, which…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 Khoa Tuan Nguyen , Ganghee Jang , Tran Anh Tuan , Won-ki Jeong

Identifying abnormal patterns in electroencephalography (EEG) remains the cornerstone of diagnosing several neurological diseases. The current clinical EEG review process relies heavily on expert visual review, which is unscalable and…

Signal Processing · Electrical Eng. & Systems 2023-02-07 Teja Gupta , Neeraj Wagh , Samarth Rawal , Brent Berry , Gregory Worrell , Yogatheesan Varatharajah

Reconstructing the intricate local morphology of neurons and their long-range projecting axons can address many connectivity related questions in neuroscience. The main bottleneck in connectomics pipelines is correcting topological errors,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Anna Grim , Jayaram Chandrashekar , Uygar Sumbul

While imaging techniques at macro and mesoscales have garnered substantial attention and resources, microscale Volume Electron Microscopy (vEM) imaging, capable of revealing intricate vascular details, has lacked the necessary benchmarking…

Computer Vision and Pattern Recognition · Computer Science 2024-08-16 Jia Wan , Wanhua Li , Jason Ken Adhinarta , Atmadeep Banerjee , Evelina Sjostedt , Jingpeng Wu , Jeff Lichtman , Hanspeter Pfister , Donglai Wei

Mammalian whole-brain connectomes are a foundational ingredient for holistic understanding of brains. Indeed, imaging connectomes at sufficient resolution to densely reconstruct cellular morphology and synapses represents a longstanding…

Neurons and Cognition · Quantitative Biology 2025-02-03 Logan Thrasher Collins , Todd Huffman , Randal Koene

Reconstructing visual stimulus images is a significant task in neural decoding, and up to now, most studies consider the functional magnetic resonance imaging (fMRI) as the signal source. However, the fMRI-based image reconstruction methods…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Hongguang Pan , Zhuoyi Li , Yunpeng Fu , Xuebin Qin , Jianchen Hu

Large-scale modelling of three-dimensional controlled-source electromagnetic (CSEM) surveys used to be feasible only for large companies and research consortia. This has changed over the last few years, and today there exists a selection of…

Segmentation of brain structures on magnetic resonance imaging (MRI) is a highly relevant neuroimaging topic, as it is a prerequisite for different analyses such as volumetry or shape analysis. Automated segmentation facilitates the study…

Accurate cell counting is essential in various biomedical research and clinical applications, including cancer diagnosis, stem cell research, and immunology. Manual counting is labor-intensive and error-prone, motivating automation through…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Abdurahman Ali Mohammed , Catherine Fonder , Ying Wei , Wallapak Tavanapong , Donald S Sakaguchi , Qi Li , Surya K. Mallapragada
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