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We present a novel approach to automatically segment magnetic resonance (MR) images of the human brain into anatomical regions. Our methodology is based on a deep artificial neural network that assigns each voxel in an MR image of the brain…

Computer Vision and Pattern Recognition · Computer Science 2015-06-26 Alexandre de Brebisson , Giovanni Montana

Recently deep learning has been witnessing widespread adoption in various medical image applications. However, training complex deep neural nets requires large-scale datasets labeled with ground truth, which are often unavailable in many…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Wentao Zhu , Yeeleng S. Vang , Yufang Huang , Xiaohui Xie

Large, carefully partitioned datasets are essential to train neural networks and standardize performance benchmarks. As a result, we have set up new repositories to make our electron microscopy datasets available to the wider community.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-21 Jeffrey M. Ede

Cryo-Electron Microscopy (cryo-EM) has emerged as a key technology to determine the structure of proteins, particularly large protein complexes and assemblies in recent years. A key challenge in cryo-EM data analysis is to automatically…

Biomolecules · Quantitative Biology 2023-04-04 Nabin Giri , Raj S. Roy , Jianlin Cheng

The inability to acquire clean high-resolution (HR) electron microscopy (EM) images over a large brain tissue volume hampers many neuroscience studies. To address this challenge, we propose a deep-learning-based image super-resolution (SR)…

Computer Vision and Pattern Recognition · Computer Science 2024-01-29 Mohammad Khateri , Morteza Ghahremani , Alejandra Sierra , Jussi Tohka

Cryo-electron microscopy (cryo-EM) is a powerful technique for determining high-resolution 3D biomolecular structures from imaging data. Its unique ability to capture structural variability has spurred the development of heterogeneous…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Minkyu Jeon , Rishwanth Raghu , Miro Astore , Geoffrey Woollard , Ryan Feathers , Alkin Kaz , Sonya M. Hanson , Pilar Cossio , Ellen D. Zhong

Deep learning has the potential to improve colonoscopy by enabling 3D reconstruction of the colon, providing a comprehensive view of mucosal surfaces and lesions, and facilitating the identification of unexplored areas. However, the…

Cryo-electron microscopy (cryo-EM) is a powerful imaging technique for reconstructing three-dimensional molecular structures from noisy tomographic projection images of randomly oriented particles. We introduce a new data fusion framework,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Joe Kileel , Oscar Mickelin , Amit Singer , Sheng Xu

The reconstruction of 3D objects from brain signals has gained significant attention in brain-computer interface (BCI) research. Current research predominantly utilizes functional magnetic resonance imaging (fMRI) for 3D reconstruction…

Graphics · Computer Science 2025-05-06 Xia Deng , Shen Chen , Jiale Zhou , Lei Li

Purpose Automated segmentation of anatomical structures in medical image analysis is a prerequisite for autonomous diagnosis as well as various computer and robot aided interventions. Recent methods based on deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Max-Heinrich Laves , Jens Bicker , Lüder A. Kahrs , Tobias Ortmaier

Background Analyzing images to accurately estimate the number of different cell types in the brain using automatic methods is a major objective in neuroscience. The automatic and selective detection and segmentation of neurons would be an…

Image and Video Processing · Electrical Eng. & Systems 2024-10-07 Antonio LaTorre , Lidia Alonso-Nanclares , José María Peña , Javier De Felipe

This study investigates a 3D and fully convolutional neural network (CNN) for subcortical brain structure segmentation in MRI. 3D CNN architectures have been generally avoided due to their computational and memory requirements during…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 J. Dolz , C. Desrosiers , I. Ben Ayed

We present 14 autoencoders, 15 kernels and 14 multilayer perceptrons for electron micrograph restoration and compression. These have been trained for transmission electron microscopy (TEM), scanning transmission electron microscopy (STEM)…

Computer Vision and Pattern Recognition · Computer Science 2018-08-30 Jeffrey M. Ede

Every year, millions of brain MRI scans are acquired in hospitals, which is a figure considerably larger than the size of any research dataset. Therefore, the ability to analyse such scans could transform neuroimaging research. Yet, their…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Benjamin Billot , Colin Magdamo , You Cheng , Steven E. Arnold , Sudeshna Das , Juan. E. Iglesias

Cryogenic electron microscopy (cryo-EM) has become an enabling technology in drug discovery and in understanding molecular bases of disease by producing near-atomic resolution (less than 0.4 nm) 3D reconstructions of biological…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Hong Xu , David E. Timm , Shireen Y. Elhabian

Transmission electron microscope (TEM) images are often corrupted by noise, hindering their interpretation. To address this issue, we propose a deep learning-based approach using simulated images. Using density functional theory…

Materials Science · Physics 2025-01-22 Jinwoong Chae , Sungwook Hong , Sungkyu Kim , Sungroh Yoon , Gunn Kim

Decoding visual information from electroencephalography (EEG) has recently achieved promising results, primarily focusing on reconstructing two-dimensional (2D) images from brain activity. However, the reconstruction of three-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Emanuele Balloni , Emanuele Frontoni , Chiara Matti , Marina Paolanti , Roberto Pierdicca , Emiliano Santarnecchi

The human brain is the most complex object of study we encounter today. Mapping the neuronal-level connections between the more than 80 billion neurons in the brain is a hopeless task for science. By the recent advancement of magnetic…

Neurons and Cognition · Quantitative Biology 2020-09-01 Balint Varga , Vince Grolmusz

Accurate cortical surface reconstruction from magnetic resonance imaging (MRI) data is crucial for reliable neuroanatomical analyses. Current methods have to contend with complex cortical geometries, strict topological requirements, and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Kaveh Moradkhani , R Jarrett Rushmore , Sylvain Bouix

Electroencephalography (EEG) is a generally used neuroimaging approach in brain-computer interfaces due to its non-invasive characteristics and convenience, making it an effective tool for understanding human intentions. Therefore, recent…

Signal Processing · Electrical Eng. & Systems 2024-11-19 Sung-Jin Kim , Dae-Hyeok Lee , Hyeon-Taek Han
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