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FRET measurements can provide dynamic spatial information on length scales smaller than the diffraction limit of light. Several methods exist to measure FRET between fluorophores, including Fluorescence Lifetime Imaging Microscopy (FLIM),…
Diffuse optical imaging (DOI) offers valuable insights into scattering mediums, but the quest for high-resolution imaging often requires dense sampling strategies, leading to higher imaging errors and lengthy acquisition times. This work…
The "Reduced Speed of Light" (RSL) approximation is commonly used to speed up radiative transfer calculations in cosmological simulations. However, it has been shown previously that the RSL approximation leads to photon non-conservation in…
Scanning transmission electron microscopy (STEM) has a broad range of applications in materials characterization, including real-space imaging, spectroscopy, and diffraction, at length scales from the micron to sub-{\AA}ngstr\"om. The…
The intra-beam repulsions play a significant role in determining the performances of free-electron devices when an high brilliance of the beam is required. The transversal and longitudinal spread of the beam, its energy and density are…
Atomic resolution imaging in transmission electron microscopy (TEM) and scanning TEM (STEM) of light elements in electron-transparent materials has long been a challenge. Biomolecular materials, for example, are rapidly altered when…
Conventional LIDAR systems require hundreds or thousands of photon detections to form accurate depth and reflectivity images. Recent photon-efficient computational imaging methods are remarkably effective with only 1.0 to 3.0 detected…
Scalable atom-based quantum platforms for simulation, computing, and metrology require fast high-fidelity, low-loss imaging of individual atoms. Standard fluorescence detection methods rely on continuous cooling, limiting the detection…
The purpose of this study was to show how advanced concepts of compact, lossless and "Time Of Flight" (TOF) capable electronics similar to those foreseen for the LHC and ILC experiments could be fairly and easily transferred to the medical…
Our interest has been to study the effect that scattered radiation has on contrast, signal-to-noise ratio and thickness reconstruction in digital mammographies. Using the GEANT code we have performed Monte-Carlo simulations of 25 kVp Mo/Mo…
Future orbiting observatories will survey large areas of sky in order to constrain the physics of dark matter and dark energy using weak gravitational lensing and other methods. Lossy compression of the resultant data will improve the cost…
High-power hadron accelerators have strict limits on fractional beam loss. In principle, once a high-quality beam is set up in an acceptable state, beam loss should remain steady. However, in practice, there are many trips in operational…
High-resolution numerical simulations including feedback and aimed at calculating the escape fraction (fesc) of hydrogen-ionizing photons often assume stellar radiation based on single-stellar population synthesis models. However, strong…
A simple method to reduce the numerical cost in free electron laser (FEL) simulations is presented, which is based on retrieving a spatially-coherent component of microbunching to suppress artifact effects that can potentially overestimate…
To obtain an accurate cosmological inference from upcoming weak lensing surveys such as the one conducted by Euclid, the shear measurement requires calibration using galaxy image simulations. We study the efficiency of different noise…
We investigate data compression schemes for proposed all-sky diffraction-limited visible/NIR sky surveys aimed at the dark energy problem. We show that lossy square-root compression to 1 bit of noise per pixel, followed by standard lossless…
Compact direct electron detectors are becoming increasingly popular in electron microscopy applications including electron backscatter diffraction, as they offer an opportunity for low cost and accessible microstructural analysis. In this…
When characterising beam-sensitive materials in the scanning transmission electron microscope (STEM), low-dose techniques are essential for the reliable observation of samples in their true state. A simple route to minimise both the total…
X-rays have widespread applications in science and industry, but developing a simple, compact, and high-quality X-ray source remains a challenge. Our collaboration has explored the possible use of channeling radiation driven by a 50 MeV…
Coherent X-ray photons with energies higher than 50 keV offer new possibilities for imaging nanoscale lattice distortions in bulk crystalline materials using Bragg peak phase retrieval methods. However, the compression of reciprocal space…