Related papers: Cell fusion through slime mold network dynamics
Plasmodium of \emph{Physarum polycephalum} is a single cell visible by unaided eye. On a non-nutrient substrate the plasmodium propagates as a traveling localization, as a compact wave-fragment of protoplasm. The plasmodium-localization…
This paper presents EINCASM, a prototype system employing a novel framework for studying emergent intelligence in organisms resembling slime molds. EINCASM evolves neural cellular automata with NEAT to maximize cell growth constrained by…
Our knowledge of how individual cells self-organize to form complex multicellular systems is being revolutionized by a data outburst, coming from high-throughput experimental breakthroughs such as single-cell RNA sequencing and spatially…
We implement Kolmogorov-Uspensky machine on a plasmodium of true slime mold {\em Physarum polycephalum}. We provide experimental findings on realization of the machine instructions, illustrate basic operations, and elements of programming.
How do non-neural organisms, such as the slime mould \textit{Physarum polycephalum}, anticipate periodic events in their environment? We present a minimal, biologically inspired reservoir model that demonstrates simple temporal anticipation…
In laboratory experiments we demonstrate that protoplasmic tubes of acellular slime mould \emph{Physarum polycephalum} show current versus voltage profiles consistent with memristive systems and that the effect is due to the living…
Cell-based, mathematical modeling of collective cell behavior has become a prominent tool in developmental biology. Cell-based models represent individual cells as single particles or as sets of interconnected particles, and predict the…
The German motorway, or 'autobahn', is characterised by long traditions, meticulous state planning, historical misbalance between West and East Germany's transport networks, and highest increase in traffic in modern Europe, posing a need…
We construct electronic oscillator from acellular slime mould Physarum polycephalum. The slime mould oscillator is made of two electrodes connected by a protoplasmic tube of the living slime mould. A protoplasmic tube has an average…
Building mathematical models of brains is difficult because of the sheer complexity of the problem. One potential starting point is through basal cognition, which gives abstract representation of a range of organisms without central nervous…
Recently, it was shown that the amoeba-like cell {\it Physarum polycephalum} when exposed to a pattern of periodic environmental changes learns and adapts its behavior in anticipation of the next stimulus to come. Here we show that such…
The plasmodium of Physarum polycephalum is renowned for spanning sources of nutrients with networks of protoplasmic tubes. The networks transport nutrients and metabolites across the plasmodium's body. To imitate a hypothetical colonisation…
Unicellular organisms exhibit elaborate collective behaviors in response to environmental cues. These behaviors are controlled by complex biochemical networks within individual cells and coordinated through cell-to-cell communication.…
We investigate morphologies of proliferating cellular tissue using a newly developed numerical simulation model for mechanical cell division. The model reproduces structures of simple multi-cellular organisms via simple rules for selective…
Coordination of cytoplasmic flows on large scales in space and time are at the root of many cellular processes, including growth, migration or division. These flows are driven by organized contractions of the actomyosin cortex. In order to…
The coupling of the internal mechanisms of cell polarization to cell shape deformations and subsequent cell crawling poses many interdisciplinary scientific challenges. Several mathematical approaches have been proposed to model the…
Roman Empire is renowned for sharp logical design and outstanding building quality of its road system. Many roads built by Romans are still use in continental Europe and UK. The Roman roads were built for military transportations with…
Hybrid modeling provides an effective solution to cope with multiple time scales dynamics in systems biology. Among the applications of this method, one of the most important is the cell cycle regulation. The machinery of the cell cycle,…
Nowadays, multiscale modelling is recognized as the most suitable way to study biological processes. Indeed, almost every phenomenon in nature exhibits a multiscale behaviour, i.e., it is the outcome of interactions that occur at different…
Network-forming organisms, like fungi and slime molds, dynamically reorganize their networks during foraging. The resulting re-routing of resource flows within the organism's network can significantly impact local ecosystems. In current…