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Optimization of fluid transport in the slime mold Physarum polycephalum has been the subject of several modeling efforts in recent literature. Existing models assume that the tube adaptation mechanism in P. polycephalum's tubular network is…

Tissues and Organs · Quantitative Biology 2019-07-01 Vincenzo Bonifaci

Plasmodium of Physarum polycephalum is a large cell, visible by unaided eye, which exhibits sophisticated patterns of foraging behaviour. The plasmodium's behaviour is well interpreted in terms of computation, where data are spatially…

Pattern Formation and Solitons · Physics 2012-06-25 Andrew Adamatzky

Slime mould of Physarum polycephalum is a large cell exhibiting rich spatial non-linear electrical characteristics. We exploit the electrical properties of the slime mould to implement logic gates using a flexible hardware platform designed…

Emerging Technologies · Computer Science 2016-07-11 Simon Harding , Jan Koutnik , Klaus Greff , Jurgen Schmidhuber , Andy Adamatzky

The slime mould Physarum polycephalum has emerged as a model for self-organisation and coordination of contractile activity at large spatial scales. This self-organisation largely results from cytoplasmic flows generated by propagating…

Soft Condensed Matter · Physics 2025-09-23 Raphael Saiseau , Valentin Busson , Marc Durand

The giant single-celled slime mould Physarum polycephalum exhibits complex morphological adaptation and amoeboid movement as it forages for food and may be seen as a minimal example of complex robotic behaviour. Swarm computation has…

Multiagent Systems · Computer Science 2012-12-04 Jeff Jones , Andrew Adamatzky

In the realm of biological flow networks, the ability to dynamically adjust to varying demands is paramount. Drawing inspiration from the remarkable adaptability of Physarum polycephalum, we present a novel physical mechanism tailored to…

Soft Condensed Matter · Physics 2023-10-05 Vidyesh Rao Anisetti , Ananth Kandala , J. M. Schwarz

Multi-nucleated cells exist in all domains of life, ranging from animals, plants and fungi to single-celled organisms such as the slime mold Physarum polycephalum. The large cell size, in the case of Physarum reaching centimeters and more,…

Biological Physics · Physics 2026-05-12 Johnny Tong , Kaspar Wachinger , Fabian K. Henn , Nico Schramma , Siyu Chen , Karen Alim

Physarum polycephalum is a large single amoeba cell, which in its plasmodial phase,forages and connects nearby food sources with protoplasmic tubes. The organism forages for food by growing these tubes towards detected food stuffs, this…

Emerging Technologies · Computer Science 2014-06-10 James G. H. Whiting , Ben P. J. de Lacy Costello , Andrew Adamatzky

The slime mould Physarum polycephalum is a suitable candidate organism for soft-matter robotics because it exhibits controllable transport, movement and guidance behaviour. Physarum may be considered as a smart computing and actuating…

Adaptation and Self-Organizing Systems · Physics 2012-12-05 Soichiro Tsuda , Jeff Jones , Andrew Adamatzky

The slime mould Physarum polycephalum is known to construct proto- plasmic transport networks which approximate proximity graphs by forag- ing for nutrients during its plasmodial life cycle stage. In these networks, nodes are represented by…

Emerging Technologies · Computer Science 2015-11-19 Jeff Jones , Richard Mayne , Andrew Adamatzky

The slime mould Physarum polycephalum displays adaptive transport dynamics and network formation that have inspired its use as a model of biological computation. We develop a Lagrangian formulation of Physarum's adaptive dynamics on…

Neurons and Cognition · Quantitative Biology 2025-11-12 Ricard Solé , Jordi Pla-Mauri

Acellular slime mould Physarum polycephalum is a popular now user-friendly living substrate for designing of future and emergent sensing and computing devices. P. polycephalum exhibits regular patterns of oscillations of its surface…

Emerging Technologies · Computer Science 2013-12-17 Andrew Adamatzky

Plasmodium of Physarum polycephalum is a single cell visible by unaided eye. During its foraging behaviour the cell spans spatially distributed sources of nutrients with a protoplasmic network. Geometrical structure of the protoplasmic…

Pattern Formation and Solitons · Physics 2015-05-14 Andrew Adamatzky , Jeff Jones

Plasmodium of Physarum polycephalum is a single cell visible by unaided eye, which spans sources of nutrients with its protoplasmic network. In a very simple experimental setup we recorded electric potential of the propagating plasmodium.…

Pattern Formation and Solitons · Physics 2011-07-18 Andrew Adamatzky , Jeff Jones

P. polycephalum may be considered as a spatially represented parallel unconventional computing substrate, but how can this `computer' be programmed? In this paper we examine and catalogue individual low-level mechanisms which may be used to…

Emerging Technologies · Computer Science 2016-10-23 Jeff Jones

The model organism Physarum polycephalum is known to perform decentralised problem solving despite absence of nervous system. Experimental evidence and modelling studies have linked these abilities, and in particular maze-solving, to some…

Biological Physics · Physics 2026-02-19 Daniele Proverbio , Giulia Giordano

Many cells face search problems, such as finding food, mates or shelter, where their success depends on their search strategy. In contrast to other unicellular organisms, the slime mold Physarum polycephalum forms a giant network-shaped…

Biological Physics · Physics 2024-09-20 Lucas Tröger , Florian Goirand , Karen Alim

During the last years, a well studied biological substrate, namely Physarum polycephalum, has been proven efficient on finding appropriate and efficient solutions in hard to solve complex mathematical problems. The plasmodium of P.…

Collective movement occurs in living systems where the simple movements of individual members of a pop- ulation are combined to generate movement of the collective as a whole, displaying complex dynamics which cannot be found in the…

Emerging Technologies · Computer Science 2015-11-25 Jeff Jones

Belgium is amongst few artificial countries, established on purpose, when Dutch and French speaking parts were joined in a single unit. This makes Belgium a particularly interesting testbed for studying bio-inspired techniques for…

Adaptation and Self-Organizing Systems · Physics 2011-12-21 Andrew Adamatzky , Bernard De Baets , Wesley Van Dessel