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Decision-making is the process of selecting an action among alternatives, allowing biological and artificial systems to navigate complex environments and optimize behavior. While neural systems rely on neuron-based sensory processing and…

Biological Physics · Physics 2025-06-17 Lisa Schick , Emily Eichenlaub , Fabian Drexel , Alexander Mayer , Siyu Chen , Marcus Roper , Karen Alim

The Phychip project is a collaborative European research initiative to design and implement computation using the organism Physarum polycephalum; it is funded by the Seventh Framework Programme (FP7) by the European Commission within CORDIS…

Emerging Technologies · Computer Science 2014-11-26 James G. H. Whiting , Ben P. J. de Lacy Costello , Andrew Adamatzky

We experimentally derived a unique one-to-one mapping between a range of selected bioactive chemicals and patterns of oscillations of the slime mould's extacellular electrical potential.

Emerging Technologies · Computer Science 2013-12-17 James G. H. Whiting , Ben P. J. de Lacy Costello , Andrew Adamatzky

Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a…

Quantitative Methods · Quantitative Biology 2017-10-25 Felix Bäuerle , Mirna Kramar , Karen Alim

We present Monte Carlo Physarum Machine: a computational model suitable for reconstructing continuous transport networks from sparse 2D and 3D data. MCPM is a probabilistic generalization of Jones's 2010 agent-based model for simulating the…

Cosmology and Nongalactic Astrophysics · Physics 2022-04-05 Oskar Elek , Joseph N. Burchett , J. Xavier Prochaska , Angus G. Forbes

Plasmodium of acellular slime mould Physarum polycephalum is a very large eukaryotic microbe visible to the unaided eye. During its foraging behaviour the plasmodium spans sources of nutrients with a network of protoplasmic tubes. In this…

Adaptation and Self-Organizing Systems · Physics 2012-09-14 Andrew Adamatzky , Michael Lees , Peter M. A. Sloot

The evolution of multicellular organisms from monocellular ancestors represents one of the greatest advances of the history of life. The assembly of such multicellular organisms requires signalling and response between cells: over millions…

Cell Behavior · Quantitative Biology 2007-05-23 Graeme J. Ackland , Richard D. L. Hanes , Morrel H. Cohen

A dynamic self-organized morphology is the hallmark of network-shaped organisms like slime moulds and fungi. Organisms continuously re-organize their flexible, undifferentiated body plans to forage for food. Among these organisms the slime…

Biological Physics · Physics 2019-03-27 Karen Alim

Active fluid transport is a hallmark of many biological transport networks. While animal circulatory systems generally rely on a single heart to drive flows, other organisms employ decentralized local pumps to distribute fluids and…

Biological Physics · Physics 2024-01-04 Adam B. Dionne , Katharine E. Jensen , Henrik Ronellenfitsch

Plasmodium of Physarum polycephalum is a single cell visible by unaided eye. During its foraging behavior the cell spans spatially distributed sources of nutrients with a protoplasmic network. Geometrical structure of the protoplasmic…

Pattern Formation and Solitons · Physics 2015-03-17 Andrew Adamatzky , Genaro J. Martinez , Sergio V. Chapa-Vergara , Rene Asomoza-Palacio , Christopher R. Stephens

Computing a polygon defining a set of planar points is a classical problem of modern computational geometry. In laboratory experiments we demonstrate that a concave hull, a connected alpha-shape without holes, of a finite planar set is…

Emerging Technologies · Computer Science 2012-06-26 Andrew Adamatzky

Slime mould Physarum polycephalum builds up sophisticated networks to transport nutrients between distant part of its extended body. The slime mould's protoplasmic network is optimised for maximum coverage of nutrients yet minimum energy…

Pattern Formation and Solitons · Physics 2015-03-19 Andrew Adamatzky , Selim G. Akl

Plasmodium of acellular slime mould Physarum polycephalum exhibits traits of wave-like behaviour. The plasmodium's behaviour can be finely tuned in laboratory experiments by using herbal tablets. A single tablet acts as a fixed attractor:…

Pattern Formation and Solitons · Physics 2012-12-13 Andrew Adamatzky

In recent years, research on Physarum polycephalum has become more popular after Nakagaki et al. (2000) performed their famous experiment showing that Physarum was able to find the shortest route through a maze. Subsequent researches have…

Artificial Intelligence · Computer Science 2021-05-11 Abubakr Awad , Wei Pang , David Lusseau , George M. Coghill

Plasmodium of Physarum polycephalum is a large cell capable of solving graph-theoretic, optimization and computational geometry problems due to its unique foraging behavior. Also the plasmodium is unique biological substrate that mimics…

Adaptation and Self-Organizing Systems · Physics 2010-11-23 Andrew Adamatzky , Jeff Jones

Plasmodium stage of Physarum polycephalum behaves as a distributed dynamical pattern formation mechanism who's foraging and migration is influenced by local stimuli from a wide range of attractants and repellents. Complex protoplasmic tube…

Biological Physics · Physics 2012-04-10 Soichiro Tsuda , Jeff Jones , Andrew Adamatzky , Jonathan Mills

Slime mould plasmodia can adjust their behaviour in response to chemical trails left by themselves and other Physarum plasmodia. This simple feedback process increases their foraging efficiency. We still do not know whether other factors…

Populations and Evolution · Quantitative Biology 2019-05-17 Eilidh Stirrup , David Lusseau

In this demo, we present a novel technique for approximating topologically optimal scaffoldings for 3D printed objects using a Monte Carlo algorithm based on the foraging behavior of the Physarum polycephalum slime mold. As a case study, we…

Graphics · Computer Science 2022-12-23 Drew Ehrlich , Milad Hakimshafaei , Oskar Elek

Acellular slime mould Physarum polycephalum is a monstrously large single cell visible by an unaided eye. It shows sophisticated behavioural traits in foraging for nutrients and developing an optimal transport network of protoplasmic tubes…

Pattern Formation and Solitons · Physics 2013-05-17 Andrew Adamatzky

Plasmodium of Physarym polycephalum is an ideal biological substrate for implementing concurrent and parallel computation, including combinatorial geometry and optimization on graphs. We report results of scoping experiments on Physarum…

Robotics · Computer Science 2010-11-23 Andrew Adamatzky