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Electroencephalography provides a non-invasive and cost-effective approach for analyzing neural patterns associated with alcohol dependence. However, reported classification performance in EEG-based alcoholism studies varies considerably,…

Signal Processing · Electrical Eng. & Systems 2026-04-14 Tahir Cetin Akinci , Yuksel Celik , Omer Faruk Ertugrul

Multiple hypothesis testing is a fundamental problem in high dimensional inference, with wide applications in many scientific fields. In genome-wide association studies, tens of thousands of tests are performed simultaneously to find if any…

Methodology · Statistics 2011-11-16 Jianqing Fan , Xu Han , Weijie Gu

This work investigates the predictive potential of bipolar electroencephalogram (EEG) recordings towards efficient prediction of poor neurological outcomes. A retrospective design using a hybrid deep learning approach is utilized to…

Signal Processing · Electrical Eng. & Systems 2023-10-09 Hemin Ali Qadir , Naimahmed Nesaragi , Per Steiner Halvorsen , Ilangko Balasingham

Evidence-based medicine (EBM) holds a crucial role in clinical application. Given suitable medical articles, doctors effectively reduce the incidence of misdiagnoses. Researchers find it efficient to use large language models (LLMs)…

Computation and Language · Computer Science 2025-11-07 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bing Qin

We propose a novel linear discriminant analysis approach for the classification of high-dimensional matrix-valued data that commonly arises from imaging studies. Motivated by the equivalence of the conventional linear discriminant analysis…

Methodology · Statistics 2019-05-06 Wei Hu , Weining Shen , Hua Zhou , Dehan Kong

We introduce and compare several strategies for learning discriminative features from electroencephalography (EEG) recordings using deep learning techniques. EEG data are generally only available in small quantities, they are…

Neural and Evolutionary Computing · Computer Science 2016-01-08 Sebastian Stober , Avital Sternin , Adrian M. Owen , Jessica A. Grahn

A scientist tests a continuous stream of hypotheses over time in the course of her investigation -- she does not test a predetermined, fixed number of hypotheses. The scientist wishes to make as many discoveries as possible while ensuring…

Methodology · Statistics 2023-11-14 Ziyu Xu , Aaditya Ramdas

Electroencephalography (EEG) plays a significant role in the Brain Computer Interface (BCI) domain, due to its non-invasive nature, low cost, and ease of use, making it a highly desirable option for widespread adoption by the general…

Signal Processing · Electrical Eng. & Systems 2023-03-13 Giulio Tosato , Cesare M. Dalbagno , Francesco Fumagalli

The main challenges of using electroencephalogram (EEG) signals to make eye-tracking (ET) predictions are the differences in distributional patterns between benchmark data and real-world data and the noise resulting from the unintended…

Machine Learning · Computer Science 2022-08-02 Brian Xiang , Abdelrahman Abdelmonsef

This paper explores the multiple testing problem for sparse high-dimensional data with binary outcomes. We propose novel empirical Bayes multiple testing procedures based on a spike-and-slab posterior and then evaluate their performance in…

Statistics Theory · Mathematics 2025-06-16 Yu-Chien Bo Ning

Unraveling the co-expression of genes across studies enhances the understanding of cellular processes. Inferring gene co-expression networks from transcriptome data presents many challenges, including spurious gene correlations, sample…

Machine Learning · Statistics 2024-10-01 Teodora Pandeva , Martijs Jonker , Leendert Hamoen , Joris Mooij , Patrick Forré

When multiple investigators analyze a common dataset, the data reuse induces dependence across testing procedures, affecting the distribution of errors. Existing techniques of managing dependent tests require either cross-study coordination…

Statistics Theory · Mathematics 2026-04-10 Reid Dale , Jordan Rodu , Maria E. Currie , Mike Baiocchi

Algorithms that ensure reproducible findings from large-scale, high-dimensional data are pivotal in numerous signal processing applications. In recent years, multivariate false discovery rate (FDR) controlling methods have emerged,…

Methodology · Statistics 2024-01-31 Jasin Machkour , Michael Muma , Daniel P. Palomar

The growing availability of observational databases like electronic health records (EHR) provides unprecedented opportunities for secondary use of such data in biomedical research. However, these data can be error-prone and need to be…

Methodology · Statistics 2024-05-28 Sarah C. Lotspeich , Gustavo G. C. Amorim , Pamela A. Shaw , Ran Tao , Bryan E. Shepherd

The affective brain-computer interface is a crucial technology for affective interaction and emotional intelligence, emerging as a significant area of research in the human-computer interaction. Compared to single-type features, multi-type…

Human-Computer Interaction · Computer Science 2025-08-11 Xueyuan Xu , Wenjia Dong , Fulin Wei , Li Zhuo

The identification of influential observations is an important part of data analysis that can prevent erroneous conclusions drawn from biased estimators. However, in high dimensional data, this identification is challenging. Classical and…

In this paper, we propose a new test for testing the equality of two population covariance matrices in the ultra-high dimensional setting that the dimension is much larger than the sizes of both of the two samples. Our proposed methodology…

Methodology · Statistics 2023-12-19 Xiucai Ding , Yichen Hu , Zhenggang Wang

Functional brain imaging through electroencephalography (EEG) relies upon the analysis and interpretation of high-dimensional, spatially organized time series. We propose to represent time-localized frequency domain characterizations of EEG…

Current statistical inference problems in areas like astronomy, genomics, and marketing routinely involve the simultaneous testing of thousands -- even millions -- of null hypotheses. For high-dimensional multivariate distributions, these…

Methodology · Statistics 2017-04-25 Weixin Cai , Nima S. Hejazi , Alan E. Hubbard

This study investigates the potential of multimodal data integration, which combines electroencephalogram (EEG) data with sociodemographic characteristics like age, sex, education, and intelligence quotient (IQ), to diagnose mental diseases…

Machine Learning · Computer Science 2025-02-07 Himanshi Singh , Sadhana Tiwari , Sonali Agarwal , Ritesh Chandra , Sanjay Kumar Sonbhadra , Vrijendra Singh