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Increasingly, medical research is dependent on data collected for non-research purposes, such as electronic health records data (EHR). EHR data and other large databases can be prone to measurement error in key exposures, and unadjusted…

Methodology · Statistics 2020-05-13 Kyunghee Han , Thomas Lumley , Bryan E. Shepherd , Pamela A. Shaw

Electroencephalography (EEG) is a widely used technique for measuring brain activity. EEG-based signals can reveal a persons emotional state, as they directly reflect activity in different brain regions. Emotion-aware systems and EEG-based…

Machine Learning · Computer Science 2026-02-03 Ashna Purwar , Gaurav Simkar , Madhumita , Sachin Kadam

Empirical research in the social and medical sciences frequently involves testing multiple hypotheses simultaneously, increasing the risk of false positives due to chance. Classical multiple testing procedures, such as the Bonferroni…

Econometrics · Economics 2025-07-29 Sebastian Calonico , Sebastian Galiani

Predictive values are measures of the clinical accuracy of a binary diagnostic test, and depend on the sensitivity and the specificity of the test and on the disease prevalence among the population being studied. This article studies…

Other Statistics · Statistics 2024-08-14 Jose Antonio Roldan-Nofuentes

We consider jointly estimating the coefficient matrix and the error precision matrix in high-dimensional multivariate linear regression models. Bayesian methods in this context often face computational challenges, leading to previous…

Methodology · Statistics 2025-08-25 Xuan Cao , Kyoungjae Lee

Electroencephalography (EEG) signals are resultants of extremely complex brain activity. Some details of this hidden dynamics might be accessible through e.g. joint distributions $\rho_{\Delta t}$ of signals of pairs of electrodes shifted…

Signal Processing · Electrical Eng. & Systems 2023-05-30 Jarek Duda

Current pain assessment within hospitals often relies on self-reporting or non-specific EKG vital signs. This system leaves critically ill, sedated, and cognitively impaired patients vulnerable to undertreated pain and opioid overuse.…

Machine Learning · Computer Science 2025-10-08 Aavid Mathrawala , Dhruv Kurup , Josie Lau

The performances of commonly used electrocardiogram (ECG) diagnosis models have recently improved with the introduction of deep learning (DL). However, the impact of various combinations of multiple DL components and/or the role of data…

Signal Processing · Electrical Eng. & Systems 2022-08-02 Jae-Won Choi , Dae-Yong Hong , Chan Jung , Eugene Hwang , Sung-Hyuk Park , Seung-Young Roh

Deep learning based electroencephalography (EEG) signal processing methods are known to suffer from poor test-time generalization due to the changes in data distribution. This becomes a more challenging problem when privacy-preserving…

In this article, we consider the problem of testing the independence between two random variables. Our primary objective is to develop tests that are highly effective at detecting associations arising from explicit or implicit functional…

Methodology · Statistics 2025-02-21 Seetharaman P , Sagnik Das , Angshuman Roy

In this paper, we aimed at reviewing several different approaches present today in the search for more accurate diagnostic and treatment management in mental healthcare. Our focus is on mood disorders, and in particular on the major…

Neurons and Cognition · Quantitative Biology 2019-03-28 Milena Cukic Radenkovic

Electroencephalography (EEG) is a complex signal and can require several years of training to be correctly interpreted. Recently, deep learning (DL) has shown great promise in helping make sense of EEG signals due to its capacity to learn…

Machine Learning · Computer Science 2019-01-23 Yannick Roy , Hubert Banville , Isabela Albuquerque , Alexandre Gramfort , Tiago H. Falk , Jocelyn Faubert

Although there is an extensive literature on the eigenvalues of high-dimensional sample covariance matrices, much of it is specialized to independent components (IC) models -- in which observations are represented as linear transformations…

Statistics Theory · Mathematics 2023-05-05 Siyao Wang , Miles E. Lopes

In this article, we introduce a two-way factor model for a high-dimensional data matrix and study the properties of the maximum likelihood estimation (MLE). The proposed model assumes separable effects of row and column attributes and…

Methodology · Statistics 2021-03-17 Gao Zhigen , Yuan Chaofeng , Jing Bingyi , Huang Wei , Guo Jianhua

Relational data are often represented as a square matrix, the entries of which record the relationships between pairs of objects. Many statistical methods for the analysis of such data assume some degree of similarity or dependence between…

Statistics Theory · Mathematics 2013-06-26 Alexander Volfovsky , Peter D. Hoff

Using deep learning methods to classify EEG signals can accurately identify people's emotions. However, existing studies have rarely considered the application of the information in another domain's representations to feature selection in…

Signal Processing · Electrical Eng. & Systems 2023-03-22 Kexin Zhu , Xulong Zhang , Jianzong Wang , Ning Cheng , Jing Xiao

As the volume and complexity of data continue to expand across various scientific disciplines, the need for robust methods to account for the multiplicity of comparisons has grown widespread. A popular measure of type 1 error rate in…

Methodology · Statistics 2024-11-19 Jianliang He , Bowen Gang , Luella Fu

EEG based multi-dimension emotion recognition has attracted substantial research interest in human computer interfaces. However, the high dimensionality of EEG features, coupled with limited sample sizes, frequently leads to classifier…

Human-Computer Interaction · Computer Science 2025-08-08 Tianze Yu , Junming Zhang , Wenjia Dong , Xueyuan Xu , Li Zhuo

Rank-based approaches are among the most popular nonparametric methods for univariate data in tackling statistical problems such as hypothesis testing due to their robustness and effectiveness. However, they are unsatisfactory for more…

Methodology · Statistics 2023-07-04 Doudou Zhou , Hao Chen

K-complexes are an important marker of brain activity and are used both in clinical practice to perform sleep scoring, and in research. However, due to the size of electroencephalography (EEG) records, as well as the subjective nature of…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Alexey Protopopov
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