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Much of the natural variation for a complex trait can be explained by variation in DNA sequence levels. As part of sequence variation, gene-gene interaction has been ubiquitously observed in nature, where its role in shaping the development…

Applications · Statistics 2012-10-01 Shaoyu Li , Yuehua Cui

Active learning is an important technique for low-resource sequence labeling tasks. However, current active sequence labeling methods use the queried samples alone in each iteration, which is an inefficient way of leveraging human…

Computation and Language · Computer Science 2020-10-07 Rongzhi Zhang , Yue Yu , Chao Zhang

The problem of learning the structure of a high dimensional graphical model from data has received considerable attention in recent years. In many applications such as sensor networks and proteomics it is often expensive to obtain samples…

Machine Learning · Statistics 2016-04-08 Gautam Dasarathy , Aarti Singh , Maria-Florina Balcan , Jong Hyuk Park

Discovering genes with similar functions across diverse biomedical contexts poses a significant challenge in gene representation learning due to data heterogeneity. In this study, we resolve this problem by introducing a novel model called…

Machine Learning · Computer Science 2023-10-05 Tianyu Liu , Yuge Wang , Rex Ying , Hongyu Zhao

Feature selection is a machine learning technique for identifying relevant variables in classification and regression models. In single-cell RNA sequencing (scRNA-seq) data analysis, feature selection is used to identify relevant genes that…

Genomics · Quantitative Biology 2025-12-02 Selim Romero , Shreyan Gupta , Victoria Gatlin , Robert S. Chapkin , James J. Cai

Recent successes in learning-based image classification, however, heavily rely on the large number of annotated training samples, which may require considerable human efforts. In this paper, we propose a novel active learning framework,…

Computer Vision and Pattern Recognition · Computer Science 2017-01-16 Keze Wang , Dongyu Zhang , Ya Li , Ruimao Zhang , Liang Lin

Interactive segmentation is commonly used in medical image analysis to obtain precise, pixel-level labeling, typically involving iterative user input to correct mislabeled regions. However, existing approaches often fail to fully utilize…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Lijun Guo , Qian Zhou , Zidi Shi , Hua Zou , Gang Ke

We study the problem of reducing the amount of labeled training data required to train supervised classification models. We approach it by leveraging Active Learning, through sequential selection of examples which benefit the model most.…

Machine Learning · Computer Science 2019-01-18 Fedor Zhdanov

Identifying significant subsets of the genes, gene shaving is an essential and challenging issue for biomedical research for a huge number of genes and the complex nature of biological networks,. Since positive definite kernel based methods…

Machine Learning · Statistics 2018-09-06 Md. Ashad Alam , Mohammad Shahjama , Md. Ferdush Rahman

Traditional supervised 3D medical image segmentation models need voxel-level annotations, which require huge human effort, time, and cost. Semi-supervised learning (SSL) addresses this limitation of supervised learning by facilitating…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Suruchi Kumari , Aryan Das , Swalpa Kumar Roy , Indu Joshi , Pravendra Singh

Large-scale pre-trained Vision-Language Models (VLMs) have exhibited impressive zero-shot performance and transferability, allowing them to adapt to downstream tasks in a data-efficient manner. However, when only a few labeled samples are…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Ce Zhang , Simon Stepputtis , Katia Sycara , Yaqi Xie

Even though there is a plethora of research in Microarray gene expression data analysis, still, it poses challenges for researchers to effectively and efficiently analyze the large yet complex expression of genes. The feature (gene)…

Neural and Evolutionary Computing · Computer Science 2023-11-13 Mrutyunjaya Panda

Neural Network-based active learning (NAL) is a cost-effective data selection technique that utilizes neural networks to select and train on a small subset of samples. While existing work successfully develops various effective or…

Machine Learning · Computer Science 2024-06-07 Dake Bu , Wei Huang , Taiji Suzuki , Ji Cheng , Qingfu Zhang , Zhiqiang Xu , Hau-San Wong

Feature selection techniques are essential for high-dimensional data analysis. In the last two decades, their popularity has been fuelled by the increasing availability of high-throughput biomolecular data where high-dimensionality is a…

Quantitative Methods · Quantitative Biology 2024-01-18 Pengyi Yang , Hao Huang , Chunlei Liu

Large medical imaging data sets are becoming increasingly available, but ensuring sample quality without significant artefacts is challenging. Existing methods for identifying imperfections in medical imaging rely on data-intensive…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Daniele Ravi , Frederik Barkhof , Daniel C. Alexander , Lemuel Puglisi , Geoffrey JM Parker , Arman Eshaghi

Active learning seeks to reduce the amount of data required to fit the parameters of a model, thus forming an important class of techniques in modern machine learning. However, past work on active learning has largely overlooked latent…

Machine Learning · Computer Science 2024-02-20 Aditi Jha , Zoe C. Ashwood , Jonathan W. Pillow

Entity Matching (EM) is a core data cleaning task, aiming to identify different mentions of the same real-world entity. Active learning is one way to address the challenge of scarce labeled data in practice, by dynamically collecting the…

Databases · Computer Science 2020-03-31 Venkata Vamsikrishna Meduri , Lucian Popa , Prithviraj Sen , Mohamed Sarwat

Feature selection can efficiently identify the most informative features with respect to the target feature used in training. However, state-of-the-art vector-based methods are unable to encapsulate the relationships between feature samples…

Machine Learning · Computer Science 2018-09-11 Lixin Cui , Lu Bai , Zhihong Zhang , Yue Wang , Edwin R. Hancock

Sickle cell anemia, which is characterized by abnormal erythrocyte morphology, can be detected using microscopic images. Computational techniques in medicine enhance the diagnosis and treatment efficiency. However, many computational…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Victor Júnio Alcântara Cardoso , Rodrigo Moreira , João Fernando Mari , Larissa Ferreira Rodrigues Moreira

The swift advancement of single-cell RNA sequencing (scRNA-seq) technologies enables the investigation of cellular-level tissue heterogeneity. Cell annotation significantly contributes to the extensive downstream analysis of scRNA-seq data.…

Machine Learning · Computer Science 2024-11-28 Huifa Li , Jie Fu , Xinpeng Ling , Zhiyu Sun , Kuncan Wang , Zhili Chen