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Active learning aims to develop label-efficient algorithms by querying the most representative samples to be labeled by a human annotator. Current active learning techniques either rely on model uncertainty to select the most uncertain…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Sayna Ebrahimi , William Gan , Dian Chen , Giscard Biamby , Kamyar Salahi , Michael Laielli , Shizhan Zhu , Trevor Darrell

Neural networks and deep learning are changing the way that artificial intelligence is being done. Efficiently choosing a suitable network architecture and fine-tune its hyper-parameters for a specific dataset is a time-consuming task given…

Machine Learning · Computer Science 2019-05-16 David Laredo , Yulin Qin , Oliver Schütze , Jian-Qiao Sun

Microbial clades modeling is a challenging problem in biology based on microarray genome sequences, especially in new species gene isolates discovery and category. Marker family genome sequences play important roles in describing specific…

Quantitative Methods · Quantitative Biology 2019-04-22 Jingwei Liu

In statistics and machine learning, feature selection is the process of picking a subset of relevant attributes for utilizing in a predictive model. Recently, rough set-based feature selection techniques, that employ feature dependency to…

Machine Learning · Computer Science 2020-03-30 Seyedeh Faezeh Farahbakhshian , Milad Taleby Ahvanooey

Emerging integrative analysis of genomic and anatomical imaging data which has not been well developed, provides invaluable information for the holistic discovery of the genomic structure of disease and has the potential to open a new…

Genomics · Quantitative Biology 2014-09-16 Junhai Jiang , Nan Lin , Shicheng Guo , Jinyun Chen , Momiao Xiong

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Multimodal single-cell technologies enable the simultaneous collection of diverse data types from individual cells, enhancing our understanding of cellular states. However, the integration of these datatypes and modeling the…

Machine Learning · Computer Science 2023-11-22 Bhavya Mehta , Nirmit Deliwala , Madhav Chandane

The availability of large labeled datasets is the key component for the success of deep learning. However, annotating labels on large datasets is generally time-consuming and expensive. Active learning is a research area that addresses the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Felix Buchert , Nassir Navab , Seong Tae Kim

Risk-based active learning is an approach to developing statistical classifiers for online decision-support. In this approach, data-label querying is guided according to the expected value of perfect information for incipient data points.…

Machine Learning · Computer Science 2022-06-28 Aidan J. Hughes , Lawrence A. Bull , Paul Gardner , Nikolaos Dervilis , Keith Worden

We introduce a new framework for sample-efficient model evaluation that we call active testing. While approaches like active learning reduce the number of labels needed for model training, existing literature largely ignores the cost of…

Machine Learning · Statistics 2021-06-15 Jannik Kossen , Sebastian Farquhar , Yarin Gal , Tom Rainforth

During recent years, active learning has evolved into a popular paradigm for utilizing user's feedback to improve accuracy of learning algorithms. Active learning works by selecting the most informative sample among unlabeled data and…

Machine Learning · Computer Science 2016-11-17 Alireza Ghasemi , Hamid R. Rabiee , Mohsen Fadaee , Mohammad T. Manzuri , Mohammad H. Rohban

Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the resolution of individual cells, providing unprecedented insights into cellular heterogeneity and complex biological systems. This paper…

Other Quantitative Biology · Quantitative Biology 2024-06-11 Megha Patel , Nimish Magre , Himanshi Motwani , Nik Bear Brown

Single-cell RNA sequencing (scRNA-seq) data analysis is pivotal for understanding cellular heterogeneity. However, the high sparsity and complex noise patterns inherent in scRNA-seq data present significant challenges for traditional…

Genomics · Quantitative Biology 2024-08-13 Wenwen Min , Zhen Wang , Fangfang Zhu , Taosheng Xu , Shunfang Wang

Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests…

Machine Learning · Computer Science 2019-08-20 Sterling Ramroach , Melford John , Ajay Joshi

Machine Learning methods have of late made significant efforts to solving multidisciplinary problems in the field of cancer classification using microarray gene expression data. Feature subset selection methods can play an important role in…

Computational Engineering, Finance, and Science · Computer Science 2013-03-04 G. Prat , Ll. Belanche

Single-cell sequencing has a significant role to explore biological processes such as embryonic development, cancer evolution, and cell differentiation. These biological properties can be presented by a two-dimensional scatter plot.…

Genomics · Quantitative Biology 2021-10-19 Ziyi Liu , Minghui Liao , Fulin luo , Bo Du

Background: Single-cell RNA sequencing (scRNA-seq) is a powerful profiling technique at the single-cell resolution. Appropriate analysis of scRNA-seq data can characterize molecular heterogeneity and shed light into the underlying cellular…

Applications · Statistics 2019-08-05 Siamak Zamani Dadaneh , Paul de Figueiredo , Sing-Hoi Sze , Mingyuan Zhou , Xiaoning Qian

Objective: Brain networks have gained increasing recognition as potential biomarkers in mental health studies, but there are limited approaches that can leverage complex brain networks for accurate classification. Our goal is to develop a…

Methodology · Statistics 2022-05-25 Jin Ming , Suprateek Kundu

Single-cell RNA sequencing (scRNA-seq) enables researchers to analyze gene expression at single-cell level. One important task in scRNA-seq data analysis is unsupervised clustering, which helps identify distinct cell types, laying down the…

Genomics · Quantitative Biology 2023-12-29 Weikang Jiang , Jinxian Wang , Jihong Guan , Shuigeng Zhou

Various approaches to gene selection for cancer classification based on microarray data can be found in the literature and they may be grouped into two categories: univariate methods and multivariate methods. Univariate methods look at each…

Quantitative Methods · Quantitative Biology 2015-06-18 Min Xu , Rudy Setiono
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