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In today's world of big data, computational analysis has become a key driver of biomedical research. Recent exponential growth in the volume of available omics data has reshaped the landscape of contemporary biology, creating demand for a…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-09 Jaqueline J. Brito , Thiago Mosqueiro , Jeremy Rotman , Victor Xue , Douglas J. Chapski , Juan De la Hoz , Paulo Matias , Lana Martin , Alex Zelikovsky , Matteo Pellegrinni , Serghei Mangul

Digital holographic microscopy is an emerging potentially low-cost alternative to conventional light microscopy for micro-object imaging on earth, underwater and in space. Immediate access to micron-scale objects however requires a…

Optics · Physics 2019-04-10 Stephan Amann , Max von Witzleben , and Stefan Breuer

Purpose: To describe the current properties and capabilities of an open-source hardware and software package that is being developed by many sites internationally with the aim of providing an inexpensive yet flexible platform for low-cost…

Microscopes are essential for biomechanics and hydrodynamical investigation of small aquatic organisms. We report a DIY microscope (GLUBscope) that enables the visualization of organisms from two orthogonal imaging planes (top and side…

Quantitative Methods · Quantitative Biology 2023-07-26 Brian T. Le , Katherine M. Auer , David A. Lopez , Justin P. Shum , Brian Suarsana , Ga-Young Kelly Suh , Per Niklas Hedde , Siavash Ahrar

In order to image live cells for prolonged periods of time, an Arduino-based, low-cost imaging incubator was constructed. The imaging incubator keeps cells viable by controlling for temperature and CO2 in order to maintain physiological…

Instrumentation and Detectors · Physics 2022-06-07 Vincent M. Rossi , Katherine C. Davidson , Lauren E. Moore

The Microgrid paradigm is gaining momentum as one of the key pieces of technology for expanding clean energy access and improving energy resilience. Most of the interest in this pertains to distinct entities that either generate electricity…

Networking and Internet Architecture · Computer Science 2023-11-29 Maitreyee Marathe , Giri Venkataramanan

We demonstrate a simple and cost-efficient scanning confocal microscope setup for use in advanced instructional physics laboratories. The setup is constructed from readily available commercial products, and the implementation of a…

Physics Education · Physics 2023-05-03 A. Reguilon , W. Bethard , E. Brekke

Modern research in the life sciences is unthinkable without computational methods for extracting, quantifying and visualizing information derived from biological microscopy imaging data. In the past decade, we observed a dramatic increase…

Bright-field microscopy, a cost-effective solution for live-cell culture, is often the only resource available, along with standard CPUs, for many low-budget labs. The inherent challenges of bright-field images -- their noisiness, low…

Quantitative Methods · Quantitative Biology 2025-11-03 Surajit Das , Pavel Zun

Light microscopy allows observing cellular features and objects with sub-micrometer resolution. As such, light microscopy has been playing a fundamental role in the life sciences for more than a hundred years. Fueled by the availability of…

Other Quantitative Biology · Quantitative Biology 2021-10-28 Johannes Hohlbein , Benedict Diederich , Barbora Marsikova , Emmanuel G. Reynaud , Seamus Holden , Wiebke Jahr , Robert Haase , Kirti Prakash

Cloud computing provides a great opportunity for scientists, as it enables large-scale experiments that cannot are too long to run on local desktop machines. Cloud-based computations can be highly parallel, long running and data-intensive,…

Software Engineering · Computer Science 2016-12-07 Maria Spichkova , Heinz W. Schmidt , Ian E. Thomas , Iman I. Yusuf , Steve Androulakis , Grischa R. Meyer

Capturing biological specimens at large scales with sub-micron resolution is crucial for biomedical research, but conventional cameras often can't handle the pixel requirements. While most microscopes use motorized stages to move samples…

Optics · Physics 2025-03-28 Charlie Kersuzan , Aymerick Bazin , Amaury Badon

The recent advancements in bio-engineering and wireless communications systems have motivated researchers to propose novel applications for telemedicine, therapeutics and human health monitoring. For instance, through wireless medical…

Systems and Control · Electrical Eng. & Systems 2021-05-03 Yevgeni Koucheryavy , Anastasia Yastrebova , Daniel P. Martins , Sasitharan Balasubramaniam

Automated and computerised control of scientific instrumentation is almost ubiquitous in the modern laboratory. Most instrumentation is controlled over decades old communication busses or is accessed via proprietary system libraries. This…

Instrumentation and Detectors · Physics 2022-01-07 Joel T. Collins , Joe Knapper , Julian Stirling , Samuel McDermott , Richard Bowman

This paper introduces the Pico-Cloud, a micro-edge cloud architecture built on ultra-minimal hardware platforms such as the Raspberry Pi Zero and comparable single-board computers. The Pico-Cloud delivers container-based virtualization,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-18 Mordechai Guri

The present work describes a website designed for remote teaching of optical measurements using lasers. It enables senior undergraduate and postgraduate students to learn theoretical aspects of the subject and also have a means to perform…

Physics Education · Physics 2018-03-02 Veena Singh , Richa Dubey , P. K. Panigrahi , K. Muralidhar

This work-in-progress paper presents the current development of a new collaborative remote laboratory platform. The results are intended to serve as a foundation for future research on collaborative work in remote laboratories. Our…

Computers and Society · Computer Science 2024-07-16 Sven Jacobs , Timo Hardebusch , Esther Franke , Henning Peters , Rashed Al Amin , Veit Wiese , Steffen Jaschke

This paper presents MicroRoboScope, a portable, compact, and versatile microrobotic experimentation platform designed for real-time, closed-loop control of both magnetic and acoustic microrobots. The system integrates an embedded computer,…

Robotics · Computer Science 2025-10-14 Max Sokolich , Yanda Yang , Subrahmanyam Cherukumilli , Fatma Ceren Kirmizitas , Sambeeta Das

Cloud computing is a cost-effective way for start-up life sciences laboratories to store and manage their data. However, in many instances the data stored over the cloud could be redundant which makes cloud-based data management inefficient…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-03-30 Kashish Ara Shakil , Ari Ora , Mansaf Alam , Shabih Shakeel

Imaging specimens over large scales and with a sub-micron resolution is instrumental to biomedical research. Yet, the number of pixels to form such an image usually exceeds the number of pixels provided by conventional cameras. While most…

Instrumentation and Detectors · Physics 2019-12-03 Gaelle Recher , Pierre Nassoy , Amaury Badon
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