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Suppose, contrary to fact, in 1950, we had put the cohort of 18 year old non-smoking American men on a stringent mandatory diet that guaranteed that no one would ever weigh more than their baseline weight established at age 18. How would…

Applications · Statistics 2008-02-06 James Robins

Yager[5] proposed a transformation for opposing(negating) the occurence of an event that is not certain using the idea that one can oppose the occurence of any uncertain event by allocating its probability among the other outcomes in the…

Probability · Mathematics 2024-04-01 Amit Srivastava

In this paper, we propose a framework for achieving long-term fair sequential decision making. By conducting both the hard and soft interventions, we propose to take path-specific effects on the time-lagged causal graph as a quantitative…

Machine Learning · Computer Science 2022-04-06 Yaowei Hu , Lu Zhang

For marginal structural models, which recently play an important role in causal inference, we consider a model selection problem in the framework of a semiparametric approach using inverse-probability-weighted estimation or doubly robust…

Methodology · Statistics 2021-02-02 Takamichi Baba , Yoshiyuki Ninomiya

The conventional nonparametric tests in survival analysis, such as the log-rank test, assess the null hypothesis that the hazards are equal at all times. However, hazards are hard to interpret causally, and other null hypotheses are more…

Methodology · Statistics 2019-01-29 Mats Julius Stensrud , Kjetil Røysland , Pål Christie Ryalen

In this article we have successfully obtained an exact solution of a particular case of SIR and SIS epidemic models given by Kermack and Mckendrick [1] for constant population, which are described by coupled nonlinear differential…

Classical Analysis and ODEs · Mathematics 2010-12-23 G. Shabbir , H. Khan , M. A. Sadiq

The attributable risk, often called the population attributable risk, is in many epidemiological contexts a more relevant measure of exposure-disease association than the excess risk, relative risk, or odds ratio. When estimating…

Statistics Theory · Mathematics 2008-12-31 Daniel B. Rubin

Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…

Machine Learning · Computer Science 2026-03-13 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Muddassar Farooq

Mortality displacement is the concept that deaths are moved forward in time (e.g., a few days, several months, and years) by exposure from when they would occur without the exposure, which is common in environmental time-series studies.…

Quantitative Methods · Quantitative Biology 2022-03-29 Honghyok Kim , Jong-Tae Lee , Roger D. Peng , Kelvin C. Fong , Michelle L. Bell

Mendelian randomization (MR) considers using genetic variants as instrumental variables (IVs) to infer causal effects in observational studies. However, the validity of causal inference in MR can be compromised when the IVs are potentially…

Methodology · Statistics 2024-02-06 Ziya Xu , Sai Li

The Randall-Sundrum (RS) model, based on a slice of warped 5D spacetime, was originally introduced to explain the apparent hierarchy between the scales of weak and gravitational interactions. Over the past decade, this model has been…

High Energy Physics - Phenomenology · Physics 2014-11-20 Hooman Davoudiasl

Separate modelling of cause specific mortality rates and their projections can yield inconsistent forecasts when the sum of deaths by cause does not match the total observed in a population. We develop a hierarchical probabilistic framework…

Applications · Statistics 2026-03-03 Andrea Nigri , Han Lin Shang , Francesco Ungolo

We consider first the mixed discrete-continuous scheme of observation in multistate models; this is a classical pattern in epidemiology because very often clinical status is assessed at discrete visit times while times of death or other…

Statistics Theory · Mathematics 2008-12-18 Daniel Commenges , Anne Gégout-Petit

We establish connections between the absorption probabilities of a class of birth-death processes with killing, and the stationary tail of a related class of birth-death processes with catastrophes. The major ingredients of the proofs are a…

Probability · Mathematics 2026-01-28 Ellen Baake , Fernando Cordero , Enrico Di Gaspero , Anton Wakolbinger

The notion of stochastic precedence between two random variables emerges as a relevant concept in several fields of applied probability. When one consider a vector of random variables $X_1,...,X_n$, this notion has a preeminent role in the…

Probability · Mathematics 2020-01-14 Emilio De Santis , Yaakov Malinovsky , Fabio Spizzichino

In his Ph.D. thesis, Ira Gessel proved a reciprocity formula for noncommutative symmetric functions which enables one to count words and permutations with restrictions on the lengths of their increasing runs. We generalize Gessel's theorem…

Combinatorics · Mathematics 2017-05-15 Yan Zhuang

Identifying causal relationships for a treatment intervention is a fundamental problem in health sciences. Randomized controlled trials (RCTs) are considered the gold standard for identifying causal relationships. However, recent…

Methodology · Statistics 2020-06-24 Riddhiman Adib , Paul Griffin , Sheikh Iqbal Ahamed , Mohammad Adibuzzaman

For a portfolio of life insurance policies observed for a stated period of time, e.g., one year, mortality is typically a rare event. When we examine the outcome of dying or not from such portfolios, we have an imbalanced binary response.…

Applications · Statistics 2020-07-31 Shuang Yin , Dipak K. Dey , Emiliano A. Valdez , Guojun Gan , Jeyaraj Vadiveloo

This paper is about how we study statistical methods. As an example, it uses the random regressions model, in which the intercept and slope of cluster-specific regression lines are modeled as a bivariate random effect. Maximizing this…

Other Statistics · Statistics 2019-05-22 James S. Hodges

A solution to control for nonresponse bias consists of multiplying the design weights of respondents by the inverse of estimated response probabilities to compensate for the nonrespondents. Maximum likelihood and calibration are two…

Methodology · Statistics 2023-10-27 Caren Hasler
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