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Recent developments for the delivery of proton and ion beam therapy have been significant, and a number of technological solutions now exist for the creation and utilisation of these particles for the treatment of cancer. In this paper we…

Accelerator Physics · Physics 2015-06-17 Hywel Owen , David Holder , Jose Alonso , Ranald MacKay

Ion beam has been used in cancer treatment, and has a unique preferable feature to deposit its main energy inside a human body so that cancer cell could be killed by the ion beam. However, conventional ion accelerator tends to be huge in…

Hadrontherapy is a novel technique of cancer radiation therapy which employs beams of charged hadrons, protons and carbon ions in particular. Due to their physical and radiobiological properties, they allow one to obtain a more conformal…

Medical Physics · Physics 2015-05-14 Saverio Braccini

It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with…

Plasma Physics · Physics 2014-05-13 K. W. D. Ledingham , P. R. Bolton , N. Shikazono , C-M. Ma

Laser acceleration promises innovation in particle beam therapy of cancer where an ultra-compact accelerator system for cancer beam therapy can become affordable to a broad range of patients. This is not feasible without the introduction of…

Proton (and ion) cancer therapy has proven to be an extremely effective even supe-rior method of treatment for some tumors 1-4. A major problem, however, lies in the cost of the particle accelerator facilities; high procurement costs…

Accelerated charged particles offer significant physical advantages over X-rays in radiotherapy. In addition to their superior depth-dose distribution, heavy ions provide notable biological benefits compared to protons. Specifically, at…

Medical Physics · Physics 2025-12-19 Jeannette Jansen , Olga Sokol , Yolanda Prezado , Marco Durante

Ion sources are key components of accelerators devoted to different types of medical applications: hadron-therapy facilities (accelerating protons or carbon ions), high-intensity accelerators for boron-neutron capture therapy (using intense…

Accelerator Physics · Physics 2018-04-24 Santo Gammino

A short overview of laser-plasma acceleration of ions is presented. The focus is on some recent experimental results and related theoretical work on advanced regimes. These latter include in particular target normal sheath acceleration…

Plasma Physics · Physics 2014-03-13 A. Macchi , A. Sgattoni , S. Sinigardi , M. Borghesi , M. Passoni

In oncology, treating cancer with a beam of photons is a well established therapeutic technique, developed over 100 years, and today over 50% of cancer patients will undergo traditional X-ray radiotherapy. However, ionizing radiation…

Medical Physics · Physics 2016-02-08 Mersini Makropoulou

Theoretical investigations show that linearly and radially polarized multiterawatt and petawatt laser beams, focused to subwavelength waist radii, can directly accelerate protons and carbon nuclei, over micron-size distances, to the…

Accelerator Physics · Physics 2010-05-25 Y. I. Salamin , Z. Harman , C. H. Keitel

Treating cancer is one of the most challenging task in medical sciences. Only limited types of cancer treatments are available as their study is still ongoing. The earlier therapies like radiotherapy with x-rays, chemotherapy are associated…

Accelerator Physics · Physics 2024-06-06 R. Kanishka

We propose an innovative fast-cycling accelerator complex conceived and designed to exploit at best the properties of accelerated ion beams for hadrontherapy. A cyclinac is composed by a cyclotron, which can be used also for other valuable…

Ion beam therapy has become a frequently applied form of cancer therapy over the last years. The advantage of ion beam therapy over conventional radiotherapy using photons is the strongly localized dose deposition, leading to a reduction of…

Instrumentation and Detectors · Physics 2020-07-28 F. Ulrich-Pur , T. Bergauer , A. Burker , S. Hatamikia , A. Hirtl , C. Irmler , S. Kaser , P. Paulitsch , F. Pitters , V. Teufelhart

Experiments on ion acceleration by irradiation of ultra-thin diamond-like carbon (DLC) foils, with thicknesses well below the skin depth, irradiated with laser pulses of ultra-high contrast and linear polarization, are presented. A maximum…

Due to its precision and limited side effects, the particle therapy of cancer is gaining popularity. The number of patients treated with protons and light ions reached 150,000 worldwide. There are currently more than 80 facilities, which…

Accelerator Physics · Physics 2020-10-01 Mariusz Sapinski

This paper reports on the conclusions of a 2013 Joint DOE/NCI Workshop, and translates clinical accelerator facility requirements into accelerator and beam-delivery technical specifications. Available or feasible accelerator technologies…

Accelerator Physics · Physics 2017-04-17 C. Johnstone , J. Taylor , R. Edgecock , R. Schulte

The essay gives an overview on researches in the field of laser ion acceleration, focusing on two types of targets. There are many types of targets while they can all be divided into targets that apply single ion or multiple ions. Mixed…

Plasma Physics · Physics 2020-09-01 Jiafei Lyu , Rui Yang , Yu Yang

The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be…

An overview of research on laser-plasma based acceleration of ions is given. The experimental state of the art is summarized and recent progress is discussed. The basic acceleration processes are briefly reviewed with an outlook on hybrid…

Plasma Physics · Physics 2017-12-19 Andrea Macchi
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