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Branch-and-Bound (B&B) algorithms are time intensive tree-based exploration methods for solving to optimality combinatorial optimization problems. In this paper, we investigate the use of GPU computing as a major complementary way to speed…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-08-21 Melab Nouredine , Imen Chakroun , Mezmaz Mohand , Daniel Tuyttens

Modern machine learning (ML) workloads increasingly rely on GPUs, yet achieving high end-to-end performance remains challenging due to dependencies on both GPU kernel efficiency and host-side settings. Although LLM-based methods show…

Multiagent Systems · Computer Science 2026-03-04 Shiyang Li , Zijian Zhang , Winson Chen , Yuebo Luo , Mingyi Hong , Caiwen Ding

Particle accelerator modeling is an important field of research and development, essential to investigating, designing and operating some of the most complex scientific devices ever built. Kinetic simulations of relativistic, charged…

Accelerator Physics · Physics 2024-05-02 Ryan T. Sandberg , Remi Lehe , Chad E. Mitchell , Marco Garten , Andrew Myers , Ji Qiang , Jean-Luc Vay , Axel Huebl

Custom CUDA kernel development is essential for maximizing GPU utilization in large-scale distributed LLM training and inference, yet manually writing kernels that jointly leverage both computation and communication remains a…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-04 Bodun Hu , Yoga Sri Varshan , Saurabh Agarwal , Aditya Akella

The advent of single-cell technology has significantly improved our understanding of cellular states and subpopulations in various tissues under normal and diseased conditions by employing data-driven approaches such as clustering and…

Vertex models represent confluent tissue by polygonal or polyhedral tilings of space, with the individual cell interacting via force laws that depend on both the geometry of the cells and the topology of the tessellation. This dependence on…

Biological Physics · Physics 2017-09-13 Daniel M. Sussman

GPU kernel optimization is fundamental to modern deep learning but remains a highly specialized task requiring deep hardware expertise. Despite strong performance in general programming, large language models (LLMs) remain uncompetitive…

Open-source simulation tools play a crucial role for neuromorphic application engineers and hardware architects to investigate performance bottlenecks and explore design optimizations before committing to silicon. Reconfigurable…

Emerging Technologies · Computer Science 2024-04-26 Sahil Hassan , Michael Inouye , Miguel C. Gonzalez , Ilkin Aliyev , Joshua Mack , Maisha Hafiz , Ali Akoglu

This work introduces a novel, modular, layered web based platform for managing machine learning experiments on grid-based High Performance Computing infrastructures. The coupling of the communication services offered by the grid, with an…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-10-12 Chairi Kiourt , Dimitris Kalles

We discuss an implementation of molecular dynamics (MD) simulations on a graphic processing unit (GPU) in the NVIDIA CUDA language. We tested our code on a modern GPU, the NVIDIA GeForce 8800 GTX. Results for two MD algorithms suitable for…

Other Condensed Matter · Physics 2008-09-10 J. A. van Meel , A. Arnold , D. Frenkel , S. F. Portegies Zwart , R. G. Belleman

Hybrid computational architectures based on the joint power of Central Processing Units and Graphic Processing Units (GPUs) are becoming popular and powerful hardware tools for a wide range of simulations in biology, chemistry, engineering,…

Instrumentation and Methods for Astrophysics · Physics 2015-06-15 Roberto Capuzzo-Dolcetta , Mario Spera

Reasoning models have recently shown remarkable progress in domains such as math and coding. However, their expert-level abilities in math and coding contrast sharply with their performance in long-horizon, interactive tasks such as web…

Computation and Language · Computer Science 2025-10-13 Xiao Yu , Baolin Peng , Michel Galley , Hao Cheng , Qianhui Wu , Janardhan Kulkarni , Suman Nath , Zhou Yu , Jianfeng Gao

Spatial organization is a core challenge for all large agent-based models with local interactions. In biological tissue models, spatial search and reinsertion are frequently reported as the most expensive steps of the simulation. One of the…

Computational Geometry · Computer Science 2016-11-11 Ilya Dmitrenok , Viktor Drobnyy , Leonard Johard , Manuel Mazzara

Coordinating large populations of grid-edge devices requires learning methods that remain fully decentralised in deployment while still respecting three-phase AC distribution-network physics. This paper proposes gradient-based multi-agent…

Machine Learning · Computer Science 2026-04-28 Yihong Zhou , Hongtai Zeng , Thomas Morstyn

With recent and rapid advancements in artificial intelligence (AI), understanding the foundation of purposeful behaviour in autonomous agents is crucial for developing safe and efficient systems. While artificial neural networks have…

Artificial Intelligence · Computer Science 2025-08-12 Aswin Paul , Moein Khajehnejad , Forough Habibollahi , Brett J. Kagan , Adeel Razi

We introduce GRiD: a GPU-accelerated library for computing rigid body dynamics with analytical gradients. GRiD was designed to accelerate the nonlinear trajectory optimization subproblem used in state-of-the-art robotic planning, control,…

Robotics · Computer Science 2023-03-03 Brian Plancher , Sabrina M. Neuman , Radhika Ghosal , Scott Kuindersma , Vijay Janapa Reddi

In this work, we propose a computationally efficient algorithm for visual policy learning that leverages differentiable simulation and first-order analytical policy gradients. Our approach decouple the rendering process from the computation…

Machine Learning · Computer Science 2025-11-12 Haoxiang You , Yilang Liu , Ian Abraham

This paper reports a case study of an application of high-resolution agent-based modeling and simulation to pandemic response planning on a university campus. In the summer of 2020, we were tasked with a COVID-19 pandemic response project…

Computers and Society · Computer Science 2024-11-11 Hiroki Sayama , Shun Cao

Multimodal large language models are evolving toward multimodal agents capable of proactively executing tasks. Most agent research focuses on GUI or embodied scenarios, which correspond to agents interacting with 2D virtual worlds or 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Longrong Yang , Zhixiong Zeng , Yufeng Zhong , Jing Huang , Liming Zheng , Lei Chen , Haibo Qiu , Zequn Qin , Lin Ma , Xi Li

Over the past decade there has been a growing interest in the development of parallel hardware systems for simulating large-scale networks of spiking neurons. Compared to other highly-parallel systems, GPU-accelerated solutions have the…

Neurons and Cognition · Quantitative Biology 2021-02-22 Bruno Golosio , Gianmarco Tiddia , Chiara De Luca , Elena Pastorelli , Francesco Simula , Pier Stanislao Paolucci