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Aberration correction is an important aspect of modern high-resolution scanning transmission electron microscopy. Most methods of aligning aberration correctors require specialized sample regions and are unsuitable for fine-tuning…

Imaging in thick biological tissues is often degraded by sample-induced aberrations, which reduce image quality and resolution, particularly in super-resolution techniques. While hardware-based adaptive optics, which correct aberrations…

The capability of the adaptive optics to correct for the segmentation error is analyzed in terms of the residual wavefront RMS and the power spectral density of the phase. The analytical model and the end-to-end simulation give…

Astrophysics · Physics 2009-11-11 Natalia Yaitskova , Christophe Verinaud

Aberration correctors are essential elements for achieving atomic resolution in state-of-the-art electron microscopes. Conventional correctors are based on a series of multipolar electron lenses, but more versatile alternatives are…

Optics · Physics 2025-01-29 Zdeněk Nekula , Thomas Juffmann , Andrea Konečná

This work addresses image restoration tasks through the lens of inverse problems using unpaired datasets. In contrast to traditional approaches -- which typically assume full knowledge of the forward model or access to paired degraded and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Giacomo Meanti , Thomas Ryckeboer , Michael Arbel , Julien Mairal

Optical microscopy offers a unique insight of biological structures with a sub-micrometer resolution and a minimum invasiveness. However, the inhomogeneities of the specimen itself can induce multiple scattering of light and optical…

Diffuse Reflectance Spectroscopy has demonstrated a strong aptitude for identifying and differentiating biological tissues. However, the broadband and smooth nature of these signals require algorithmic processing, as they are often…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Nicola Rossberg , Celina L. Li , Simone Innocente , Stefan Andersson-Engels , Katarzyna Komolibus , Barry O'Sullivan , Andrea Visentin

Scattering often limits the controlled delivery of light in applications such as biomedical imaging, optogenetics, optical trapping, and fiber-optic communication or imaging. Such scattering can be controlled by appropriately shaping the…

Optics · Physics 2019-02-19 Alex Turpin , Ivan Vishniakou , Johannes D. Seelig

We present a novel learning-based method to build a differentiable computational model of a real fluorescence microscope. Our model can be used to calibrate a real optical setup directly from data samples and to engineer point spread…

Image and Video Processing · Electrical Eng. & Systems 2023-06-12 Josue Page , Paolo Favaro

This paper proposes a non-computational method of counteracting the effect of image degradation introduced by the diffraction phenomenon in lensless microscopy. All the optical images (whether focused by lenses or not) are diffraction…

Optics · Physics 2021-04-08 Sanjeev Kumar , Manjunatha Mahadevappa , Pranab Kumar Dutta

Multiple optical scattering occurs when light propagates in a non-uniform medium. During the multiple scattering, images were distorted and the spatial information they carried became scrambled. However, the image information is not lost…

Computer Vision and Pattern Recognition · Computer Science 2021-07-30 Xinyu Gao , Yi Li , Yanqing Qiu , Bangning Mao , Miaogen Chen , Yanlong Meng , Chunliu Zhao , Juan Kang , Yong Guo , Changyu Shen

Imaging with optical resolution through highly scattering media is a long sought-after goal with important applications in deep tissue imaging. Although being the focus of numerous works, this goal was considered impractical until recently.…

Optics · Physics 2012-02-10 Ori Katz , Eran Small , Yaron Silberberg

Adaptive optics (AO) is a powerful tool to increase the imaging depth of multiphoton scanning microscopes. For highly scattering tissues, sensorless wavefront correction techniques exhibit robust performance and present a straight-forward…

Optical aberrations of optical systems cause significant degradation of imaging quality. Aberration correction by sophisticated lens designs and special glass materials generally incurs high cost of manufacturing and the increase in the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-13 Shuang Cui , Bingnan Wang , Quan Zheng

Recording and identifying faint objects through atmospheric scattering media by an optical system are fundamentally interesting and technologically important. In this work, we introduce a comprehensive model that incorporates contributions…

Optics · Physics 2024-04-24 Libang Chen , Jun Yang , Lingye Chen , Yuyang Shui , Yikun Liu , Jianying Zhou

Unsupervised change detection techniques are generally constrained to two multi-band optical images acquired at different times through sensors sharing the same spatial and spectral resolution. This scenario is suitable for a straight…

Image and Video Processing · Electrical Eng. & Systems 2018-04-10 Vinicius Ferraris , Nicolas Dobigeon , Marie Chabert

We present two complementary strategies for modeling nonlinear quantum optics in realistic integrated optical devices, where scattering loss is present. In the first strategy, we model scattering loss as an attenuation; in the second, we…

Quantum Physics · Physics 2022-10-19 Milica Banic , Luca Zatti , Marco Liscidini , J. E. Sipe

Recent machine learning techniques have dramatically changed how we process digital images. However, the way in which we capture images is still largely driven by human intuition and experience. This restriction is in part due to the many…

Image and Video Processing · Electrical Eng. & Systems 2020-02-17 Amey Chaware , Colin L. Cooke , Kanghyun Kim , Roarke Horstmeyer

Optical imaging through scattering media is a fundamental challenge in many applications. Recently, substantial breakthroughs such as imaging through biological tissues and looking around corners have been obtained by the use of…

Optics · Physics 2020-07-09 Tomer Yeminy , Ori Katz

Scattering has usually be considered as detrimental for optical focusing or imaging. Recently, more and more research has shown that strongly scattering materials can be utilized to focus coherent light by controlling or shaping the…

Optics · Physics 2017-05-24 Yanqi Qiao , Xianfeng Chen , Yajun Peng , Yuanlin Zheng