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Related papers: Mean field control problems for vaccine distributi…

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We consider mean-field control problems in discrete time with discounted reward, infinite time horizon and compact state and action space. The existence of optimal policies is shown and the limiting mean-field problem is derived when the…

Optimization and Control · Mathematics 2025-10-16 Nicole Bäuerle

We study a high-dimensional stochastic optimization problem which features both control and stopping. In particular, a central planner steers a large population of particles, and can also remove particles at any time by paying a penalty. In…

Optimization and Control · Mathematics 2026-03-24 Pierre Cardaliaguet , Joe Jackson , Panagiotis E. Souganidis

The topic of finding effective strategy to halt virus in complex network is of current interest. We propose an immunization strategy for seasonal epidemics that occur periodically. Based on the local information of the infection status from…

Applications · Statistics 2015-06-22 Shu Yan , Shaoting Tang , Sen Pei , Shijin Jiang , Zhiming Zheng

The paper uses machine learning and mathematical modeling to predict future vaccine distribution and solve the problem of allocating vaccines to different types of hospitals. They collected data and analyzed it, finding factors such as…

Computers and Society · Computer Science 2023-06-13 Baiqiao Yin , Jiaqing Yuan , Weichen Lv , Jiehui Huang , Guian Fang

Since the outbreak of COVID-19, it has rapidly evolved into a sudden and major public health emergency globally. With the variants of COVID-19, the difficulty of pandemic control continues to increase, which has brought significant costs to…

Applications · Statistics 2022-08-26 Yufei Wang , Mingzhuang Hua , Xuewu Chen , Wendong Chen , Long Cheng

Population-wide vaccination is critical for containing the SARS-CoV-2 (Covid-19) pandemic when combined with restrictive and prevention measures. In this study, we introduce SAIVR, a mathematical model able to forecast the Covid-19 epidemic…

Populations and Evolution · Quantitative Biology 2022-01-19 Mattia Angeli , Georgios Neofotistos , Marios Mattheakis , Efthimios Kaxiras

The global SARS-CoV-2 (COVID-19) pandemic highlighted the challenge of equitable vaccine distribution between high- and low-income countries. Many high-income countries were reluctant or slow to distribute extra doses of the vaccine to…

Populations and Evolution · Quantitative Biology 2024-08-21 Abraham Holleran , Susan E. Martonosi , Michael Veatch

This article is concerned with stochastic control problems for backward doubly stochastic differential equations of mean-field type, where the coefficient functions depend on the joint distribution of the state process and the control…

Probability · Mathematics 2022-05-26 Jian Song , Meng Wang

Many applications involving multi-agent systems require fulfilling safety constraints. Control barrier functions offer a systematic framework to enforce forward invariance of safety sets. Recent work extended this paradigm to mean-field…

Systems and Control · Electrical Eng. & Systems 2026-03-20 Cinzia Tomaselli , Gian Carlo Maffettone , Samy Wu Fung , Levon Nurbekyan , Mario di Bernardo

The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United…

Populations and Evolution · Quantitative Biology 2021-07-20 Dimitris Bertsimas , Vassilis Digalakis , Alexander Jacquillat , Michael Lingzhi Li , Alessandro Previero

The novel COVID-19 pandemic is a current, major global health threat. Up till now, there is no fully approved pharmacological treatment or a vaccine. In this study, simple mathematical models were employed to examine the dynamics of…

Physics and Society · Physics 2020-12-25 Ahmed S. Elgazzar

During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…

Physics and Society · Physics 2021-02-24 Marco A. Amaral , Marcelo M. de Oliveira , Marco A. Javarone

The mean-field limit in a weakly interacting stochastic many-particle system for multiple population species in the whole space is proved. The limiting system consists of cross-diffusion equations, modeling the segregation of populations.…

Analysis of PDEs · Mathematics 2019-09-04 Li Chen , Esther S. Daus , Ansgar Jüngel

In this paper, we propose a dynamical model to describe the transmission of COVID-19, which is spreading in China and many other countries. To avoid a larger outbreak in the worldwide, Chinese government carried out a series of strong…

Populations and Evolution · Quantitative Biology 2020-03-09 Jiwei Jia , Jian Ding , Siyu Liu , Guidong Liao , Jingzhi Li , Ben Duan , Guoqing Wang , Ran Zhang

Human behavior, and in particular vaccine hesitancy, is a critical factor for the control of childhood infectious disease. Here we propose a spatio-temporal behavioral epidemiology model where the vaccine propensity depends on information…

Physics and Society · Physics 2023-05-04 Malay Banerjee , Samiran Ghosh , Piero Manfredi , Alberto d'Onofrio

In this paper we study a mean field control problem in which particles are absorbed when they reach the boundary of a smooth domain. The value of the N-particle problem is described by a hierarchy of Hamilton-Jacobi equations which are…

Analysis of PDEs · Mathematics 2026-05-14 Pierre Cardaliaguet , Joe Jackson , Panagiotis E. Souganidis

Non-pharmaceutical interventions(NPIs) play an important role in the early stage control of COVID-19 pandemic. Vaccination is considered to be the inevitable course to stop the spread of SARS-CoV-2. Based on the mechanism, a SVEIR COVID-19…

Populations and Evolution · Quantitative Biology 2021-07-08 Bin-Guo Wang , Shunxiang Huang , Yongping Xiong , Ming-Zhen Xin , Jing LI , Jiangqian Zhang , Zhihui Ma

We propose a mathematical spatiotemporal epidemic SICA model with a control strategy. The spatial behavior is modeled by adding a diffusion term with the Laplace operator, which is justified and interpreted both mathematically and…

Optimization and Control · Mathematics 2022-07-12 Houssine Zine , Abderrahim El Adraoui , Delfim F. M. Torres

This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

Optimization and Control · Mathematics 2024-06-12 Rocío Balderrama , Mariana Inés Prieto , Constanza Sánchez de la Vega , Federico Vazquez

The spread of an epidemic disease and the population's collective behavioural response are deeply intertwined, influencing each other's evolution. Such a co-evolution typically has been overlooked in mathematical models, limiting their…

Dynamical Systems · Mathematics 2024-10-24 Kathinka Frieswijk , Lorenzo Zino , Mengbin Ye , Alessandro Rizzo , Ming Cao
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