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The classical Bayesian posterior arises naturally as the unique solution of several different optimization problems, without the necessity of interpreting data as conditional probabilities and then using Bayes' Theorem. For example, the…

Statistics Theory · Mathematics 2012-03-02 Theodore P. Hill , Marco Dall'Aglio

We propose a general method to carry out a valid Bayesian analysis of a finite-dimensional `targeted' parameter in the presence of a finite-dimensional nuisance parameter. We apply our methods to causal inference based on estimating…

Methodology · Statistics 2026-02-03 Magid Sabbagh , David A. Stephens

We congratulate Lee, Nadler and Wasserman (henceforth LNW) on a very interesting paper on new methodology and supporting theory [arXiv:0707.0481]. Treelets seem to tackle two important problems of modern data analysis at once. For datasets…

Applications · Statistics 2008-07-28 Nicolai Meinshausen , Peter Bühlmann

Phylogenetic networks represent evolutionary history of species and can record natural reticulate evolutionary processes such as horizontal gene transfer and gene recombination. This makes phylogenetic networks a more comprehensive…

Populations and Evolution · Quantitative Biology 2021-06-15 Remie Janssen , Pengyu Liu

We propose a method for simultaneously detecting shared and unshared communities in heterogeneous multilayer weighted and undirected networks. The multilayer network is assumed to follow a generative probabilistic model that takes into…

Social and Information Networks · Computer Science 2019-06-25 Hafiz Tiomoko Ali , Sijia Liu , Yasin Yilmaz , Romain Couillet , Indika Rajapakse , Alfred Hero

We present a method for learning treewidth-bounded Bayesian networks from data sets containing thousands of variables. Bounding the treewidth of a Bayesian greatly reduces the complexity of inferences. Yet, being a global property of the…

Artificial Intelligence · Computer Science 2016-05-12 Mauro Scanagatta , Giorgio Corani , Cassio P. de Campos , Marco Zaffalon

Using topological summaries of gene trees as a basis for species tree inference is a promising approach to obtain acceptable speed on genomic-scale datasets, and to avoid some undesirable modeling assumptions. Here we study the…

Populations and Evolution · Quantitative Biology 2017-04-17 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

Previously, we proposed a probabilistic data generation model represented by an unobservable tree and a sequential updating method to calculate a posterior distribution over a set of trees. The set is called a meta-tree. In this paper, we…

Machine Learning · Computer Science 2023-07-18 Yuta Nakahara , Toshiyasu Matsushima

Inferring evolutionary histories (phylogenetic trees) has important applications in biology, criminology and public health. However, phylogenetic trees are complex mathematical objects that reside in a non-Euclidean space, which complicates…

Methodology · Statistics 2017-10-16 Amy Willis

Phylogenetics is a classical methodology in computational biology that today has become highly relevant for medical investigation of single-cell data, e.g., in the context of cancer development. The exponential size of the tree space is,…

Populations and Evolution · Quantitative Biology 2023-01-25 Hazal Koptagel , Oskar Kviman , Harald Melin , Negar Safinianaini , Jens Lagergren

Traditionally, phylogeny and sequence alignment are estimated separately: first estimate a multiple sequence alignment and then infer a phylogeny based on the sequence alignment estimated in the previous step. However, uncertainty in the…

Applications · Statistics 2014-11-25 Heejung Shim , Bret Larget

We consider a multitype Galton-Watson process that allows for the mutation and reversion of individual types in discrete and continuous time. In this setting, we explicitly compute the time evolution of quantities such as the mean and…

Populations and Evolution · Quantitative Biology 2026-01-01 Qiao Huang , Nicolas Privault

Variational Bayes is a popular method for approximate inference but its derivation can be cumbersome. To simplify the process, we give a 3-step recipe to identify the posterior form by explicitly looking for linearity with respect to…

Machine Learning · Computer Science 2023-07-11 Mohammad Emtiyaz Khan

Recent progress in variational inference has paid much attention to the flexibility of variational posteriors. One promising direction is to use implicit distributions, i.e., distributions without tractable densities as the variational…

Machine Learning · Statistics 2018-02-26 Jiaxin Shi , Shengyang Sun , Jun Zhu

In this paper, we investigate adaptive nonlinear regression and introduce tree based piecewise linear regression algorithms that are highly efficient and provide significantly improved performance with guaranteed upper bounds in an…

Machine Learning · Computer Science 2013-12-30 N. Denizcan Vanli , Suleyman S. Kozat

Species tree estimation is a complex problem, due to the fact that different parts of the genome can have different evolutionary histories than the genome itself. One of the causes for this discord is incomplete lineage sorting (also called…

Populations and Evolution · Quantitative Biology 2019-04-09 Erin Molloy , Tandy Warnow

Terraces are potentially large sets of trees with precisely the same likelihood or parsimony score, which can be induced by missing sequences in partitioned multi-locus phylogenetic data matrices. The set of trees on a terrace can be…

Populations and Evolution · Quantitative Biology 2014-10-30 Michael J Sanderson , Michelle M. McMahon , Alexandros Stamatakis , Derrick J. Zwickl , Mike Steel

In variational inference, the benefits of Bayesian models rely on accurately capturing the true posterior distribution. We propose using neural samplers that specify implicit distributions, which are well-suited for approximating complex…

Machine Learning · Computer Science 2023-11-10 Anshuk Uppal , Kristoffer Stensbo-Smidt , Wouter Boomsma , Jes Frellsen

Probability estimation of tree topologies is one of the fundamental tasks in phylogenetic inference. The recently proposed subsplit Bayesian networks (SBNs) provide a powerful probabilistic graphical model for tree topology probability…

Populations and Evolution · Quantitative Biology 2024-09-10 Tianyu Xie , Musu Yuan , Minghua Deng , Cheng Zhang

We present a novel Bayesian approach to analysing multiple time-series with the aim of detecting abnormal regions. These are regions where the properties of the data change from some normal or baseline behaviour. We allow for the…

Applications · Statistics 2015-08-17 Lawrence Bardwell , Paul Fearnhead
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