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Related papers: Extracting Adverse Drug Events from Clinical Notes

200 papers

Adverse drug reaction (ADR) is widely concerned for public health issue. ADRs are one of most common causes to withdraw some drugs from market. Prescription event monitoring (PEM) is an important approach to detect the adverse drug…

Machine Learning · Computer Science 2014-09-03 Yihui Liu , Uwe Aickelin

The use of multiple drugs accounts for almost 30% of all hospital admission and is the 5th leading cause of death in America. Since over 30% of all adverse drug events (ADEs) are thought to be caused by drug-drug interactions (DDI), better…

Quantitative Methods · Quantitative Biology 2020-09-02 Ricky Wang

Extracting meaningful drug-related information chunks, such as adverse drug events (ADE), is crucial for preventing morbidity and saving many lives. Most ADEs are reported via an unstructured conversation with the medical context, so…

Computation and Language · Computer Science 2023-08-16 Jie Yang , Soyeon Caren Han , Siqu Long , Josiah Poon , Goran Nenadic

In this work, we present a manually annotated corpus for Adverse Event (AE) extraction from discharge summaries of elderly patients, a population often underrepresented in clinical NLP resources. The dataset includes 14 clinically…

Computation and Language · Computer Science 2025-06-19 Imane Guellil , Salomé Andres , Atul Anand , Bruce Guthrie , Huayu Zhang , Abul Hasan , Honghan Wu , Beatrice Alex

The pharmacovigilance databases consist of several case reports involving drugs and adverse events (AEs). Some methods are applied consistently to highlight all signals, i.e. all statistically significant associations between a drug and an…

Artificial Intelligence · Computer Science 2009-01-27 Alexander Estacio-Moreno , Yannick Toussaint , Cédric Bousquet

Side effects of prescribed medications are a common occurrence. Electronic healthcare databases present the opportunity to identify new side effects efficiently but currently the methods are limited due to confounding (i.e. when an…

Databases · Computer Science 2016-11-17 Jenna M. Reps , Uwe Aickelin , Jiangang Ma , Yanchun Zhang

Adverse drug reaction (ADR) is widely concerned for public health issue. ADRs are one of most common causes to withdraw some drugs from market. Prescription event monitoring (PEM) is an important approach to detect the adverse drug…

Computational Engineering, Finance, and Science · Computer Science 2013-07-08 Yihui Liu , Uwe Aickelin

Automatic monitoring of adverse drug events (ADEs) or reactions (ADRs) is currently receiving significant attention from the biomedical community. In recent years, user-generated data on social media has become a valuable resource for this…

Computation and Language · Computer Science 2023-11-21 Ilseyar Alimova , Elena Tutubalina

Relation extraction between drugs plays a crucial role in identifying drug drug interactions and predicting side effects. The advancement of machine learning methods in relation extraction, along with the development of large medical text…

Computation and Language · Computer Science 2025-10-28 Ali Fata , Hossein Rahmani , Parinaz Soltanzadeh , Amirhossein Derakhshan , Behrouz Minaei Bidgoli

Inferring causality using longitudinal observational databases is challenging due to the passive way the data are collected. The majority of associations found within longitudinal observational data are often non-causal and occur due to…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Jenna Reps , Uwe Aickelin

With the advancements in Artificial intelligence (AI) and the accumulation of healthrelated big data, it has become increasingly feasible and commonplace to leverage machine learning technologies to analyze clinical and omics metadata to…

Genomics · Quantitative Biology 2022-04-14 Attayeb Mohsen , Lokesh P. Tripathi , Kenji Mizuguchi

An accurate and detailed account of patient medications, including medication changes within the patient timeline, is essential for healthcare providers to provide appropriate patient care. Healthcare providers or the patients themselves…

Relation extraction is a central task in natural language processing (NLP) and information retrieval (IR) research. We argue that an important type of relation not explored in NLP or IR research to date is that of an event being an argument…

Computation and Language · Computer Science 2023-04-05 Ruiqi Li , Patrik Haslum , Leyang Cui

The objective of our work is to demonstrate the feasibility of utilizing deep learning models to extract safety signals related to the use of dietary supplements (DS) in clinical text. Two tasks were performed in this study. For the named…

Information Retrieval · Computer Science 2020-11-24 Yadan Fan , Sicheng Zhou , Yifan Li , Rui Zhang

Adverse Childhood Experiences (ACEs) are defined as a collection of highly stressful, and potentially traumatic, events or circumstances that occur throughout childhood and/or adolescence. They have been shown to be associated with…

Computation and Language · Computer Science 2022-08-25 Jinge Wu , Rowena Smith , Honghan Wu

Preventable adverse events as a result of medical errors present a growing concern in the healthcare system. As drug-drug interactions (DDIs) may lead to preventable adverse events, being able to extract DDIs from drug labels into a…

Computation and Language · Computer Science 2019-11-06 Tung Tran , Ramakanth Kavuluru , Halil Kilicoglu

Adverse event (AE) extraction following COVID-19 vaccines from text data is crucial for monitoring and analyzing the safety profiles of immunizations. Traditional deep learning models are adept at learning intricate feature representations…

Computation and Language · Computer Science 2024-06-27 Yiming Li , Deepthi Viswaroopan , William He , Jianfu Li , Xu Zuo , Hua Xu , Cui Tao

Adverse drug events (ADE) are prevalent and costly. Clinical trials are constrained in their ability to identify potential ADEs, motivating the development of spontaneous reporting systems for post-market surveillance. Statistical methods…

Computation and Language · Computer Science 2020-08-11 Xiruo Ding , Trevor Cohen

Combination drug therapies are treatment regimens that involve two or more drugs, administered more commonly for patients with cancer, HIV, malaria, or tuberculosis. Currently there are over 350K articles in PubMed that use the "combination…

Computation and Language · Computer Science 2023-03-30 Yuhang Jiang , Ramakanth Kavuluru

This paper deals with a skew-normal model of the relation between a dose $d > 0$ and a quantitative measure $E(d)$ of an effect of the administered drug. Precisely, $E(d)$ is a measure of the therapeutic response or a measure of a…

Methodology · Statistics 2015-04-17 Francis Lavergne , Nicolas Marie