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Related papers: Extracting Adverse Drug Events from Clinical Notes

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In this paper, we focus on the classification of tweets as sources of potential signals for adverse drug effects (ADEs) or drug reactions (ADRs). Following the intuition that text and drug structure representations are complementary, we…

Quantitative Methods · Quantitative Biology 2023-11-21 Andrey Sakhovskiy , Elena Tutubalina

Attention-based models have become the leading approach in modeling medical language for Natural Language Processing (NLP) in clinical notes. These models outperform traditional techniques by effectively capturing contextual representations…

Computation and Language · Computer Science 2025-09-26 Tariq Abdul-Quddoos , Xishuang Dong , Lijun Qian

Relation extraction (RE) is a standard information extraction task playing a major role in downstream applications such as knowledge discovery and question answering. Although decoder-only large language models are excelling in generative…

Computation and Language · Computer Science 2025-07-28 Yuhang Jiang , Ramakanth Kavuluru

Meta-analysis is a powerful tool for assessing drug safety by combining treatment-related toxicological findings across multiple studies, as clinical trials are typically underpowered for detecting adverse drug effects. However, incomplete…

Adverse drug interactions are a critical concern in pharmacovigilance, as both clinical trials and spontaneous reporting systems often lack the breadth to detect complex drug interactions. This study introduces a computational framework for…

Applications · Statistics 2025-04-02 Jules Bangard , Einar Holsbø , Kristian Svendsen , Vittorio Perduca , Etienne Birmelé

The analysis of adverse events (AEs) is a key component in the assessment of a drug's safety profile. Inappropriate analysis methods may result in misleading conclusions about a therapy's safety and consequently its benefit-risk ratio. The…

In recent years extracting relevant information from biomedical and clinical texts such as research articles, discharge summaries, or electronic health records have been a subject of many research efforts and shared challenges. Relation…

Computation and Language · Computer Science 2016-07-01 Sunil Kumar Sahu , Ashish Anand , Krishnadev Oruganty , Mahanandeeshwar Gattu

Preventable adverse drug reactions as a result of medical errors present a growing concern in modern medicine. As drug-drug interactions (DDIs) may cause adverse reactions, being able to extracting DDIs from drug labels into…

Computation and Language · Computer Science 2019-05-21 Tung Tran , Ramakanth Kavuluru , Halil Kilicoglu

The pharmaceutical industry is plagued by the problem of side effects that can occur anytime a prescribed medication is ingested. There has been a recent interest in using the vast quantities of medical data available in longitudinal…

Computational Engineering, Finance, and Science · Computer Science 2014-09-22 Jenna Reps , Jonathan M. Garibaldi , Uwe Aickelin , Daniele Soria , Jack E. Gibson , Richard B. Hubbard

Drug Names, Population Level Surveillance and the FDA's Adverse Event Reporting System: An Exploratory Data Survey of Drug Name Incidence and Prevalence, 2004-2012Q2 Purpose: To count and monitor the drug names reported in the publicly…

Computational Engineering, Finance, and Science · Computer Science 2013-09-04 Nick Williams

Mining relationships between treatment(s) and medical problem(s) is vital in the biomedical domain. This helps in various applications, such as decision support system, safety surveillance, and new treatment discovery. We propose a deep…

Machine Learning · Computer Science 2018-07-02 Veera Raghavendra Chikka , Kamalakar Karlapalem

Adverse Events (AE) are harmful events resulting from the use of medical products. Although social media may be crucial for early AE detection, the sheer scale of this data makes it logistically intractable to analyze using human agents,…

Computation and Language · Computer Science 2021-09-14 Shivam Raval , Hooman Sedghamiz , Enrico Santus , Tuka Alhanai , Mohammad Ghassemi , Emmanuele Chersoni

In document-level event extraction (DEE) task, event arguments always scatter across sentences (across-sentence issue) and multiple events may lie in one document (multi-event issue). In this paper, we argue that the relation information of…

Computation and Language · Computer Science 2022-06-08 Yuan Liang , Zhuoxuan Jiang , Di Yin , Bo Ren

Recent neural-based relation extraction approaches, though achieving promising improvement on benchmark datasets, have reported their vulnerability towards adversarial attacks. Thus far, efforts mostly focused on generating adversarial…

Computation and Language · Computer Science 2023-01-26 Luoqiu Li , Xiang Chen , Zhen Bi , Xin Xie , Shumin Deng , Ningyu Zhang , Chuanqi Tan , Mosha Chen , Huajun Chen

In the realm of cancer treatment, summarizing adverse drug events (ADEs) reported by patients using prescribed drugs is crucial for enhancing pharmacovigilance practices and improving drug-related decision-making. While the volume and…

Computation and Language · Computer Science 2025-05-08 Sofia Jamil , Aryan Dabad , Bollampalli Areen Reddy , Sriparna Saha , Rajiv Misra , Adil A. Shakur

Polypharmacy, the concurrent use of multiple drugs to treat a single condition, is common in patients managing multiple or complex conditions. However, as more drugs are added to the treatment plan, the risk of adverse drug events (ADEs)…

Machine Learning · Computer Science 2025-06-12 Natalie Wang , Casey Overby Taylor

Social media is becoming an increasingly important source of information to complement traditional pharmacovigilance methods. In order to identify signals of potential adverse drug reactions, it is necessary to first identify medical…

Artificial Intelligence · Computer Science 2015-04-28 Alejandro Metke-Jimenez , Sarvnaz Karimi

In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent…

Quantitative Methods · Quantitative Biology 2024-07-30 Yufeng Li , Wenchao Zhao , Bo Dang , Xu Yan , Weimin Wang , Min Gao , Mingxuan Xiao

The current best practice approach for the retrospective diagnosis of adverse drug events (ADEs) in hospitalized patients relies on a full patient chart review and a formal causality assessment by multiple medical experts. This evaluation…

Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is…

Machine Learning · Computer Science 2023-02-08 Bar Vered , Guy Shtar , Lior Rokach , Bracha Shapira