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Major Depressive Disorder (MDD) is a pervasive mental health condition that affects 300 million people worldwide. This work presents a novel, BiLSTM-based tri-modal model-level fusion architecture for the binary classification of depression…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Santosh V. Patapati

Background: Captured between clinical appointments using mobile devices, spoken language has potential for objective, more regular assessment of symptom severity and earlier detection of relapse in major depressive disorder. However,…

The field of natural language processing (NLP) has made significant progress with the rapid development of deep learning technologies. One of the research directions in text sentiment analysis is sentiment analysis of medical texts, which…

Computation and Language · Computer Science 2024-12-04 Yinan Chen

Pre-trained language models (LMs), such as BERT (Devlin et al., 2018) and its variants, have led to significant improvements on various NLP tasks in past years. However, a theoretical framework for studying their relationships is still…

Computation and Language · Computer Science 2022-10-24 Hao Zhang

Major depressive disorder (MDD) presents challenges in diagnosis and treatment due to its complex and heterogeneous nature. Emerging evidence indicates that reward processing abnormalities may serve as a behavioral marker for MDD. To…

Machine Learning · Computer Science 2024-07-29 Xingche Guo , Donglin Zeng , Yuanjia Wang

The current era of natural language processing (NLP) has been defined by the prominence of pre-trained language models since the advent of BERT. A feature of BERT and models with similar architecture is the objective of masked language…

Computation and Language · Computer Science 2023-07-04 Ed S. Ma

Recent advances in natural language processing (NLP) have been driven bypretrained language models like BERT, RoBERTa, T5, and GPT. Thesemodels excel at understanding complex texts, but biomedical literature, withits domain-specific…

Computation and Language · Computer Science 2025-07-28 K. Sahit Reddy , N. Ragavenderan , Vasanth K. , Ganesh N. Naik , Vishalakshi Prabhu , Nagaraja G. S

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Depression is a growing concern gaining attention in both public discourse and AI research. While deep neural networks (DNNs) have been used for recognition, they still lack real-world effectiveness. Large language models (LLMs) show strong…

Human-Computer Interaction · Computer Science 2025-08-27 Yupei Li , Shuaijie Shao , Manuel Milling , Björn W. Schuller

Objective: The majority of detailed patient information in real-world data (RWD) is only consistently available in free-text clinical documents. Manual curation is expensive and time-consuming. Developing natural language processing (NLP)…

This study investigates the detection and classification of depressive and non-depressive states using deep learning approaches. Depression is a prevalent mental health disorder that substantially affects quality of life, and early…

Quantitative Methods · Quantitative Biology 2026-01-19 Mohammad Reza Yousefi , Hajar Ismail Al-Tamimi , Amin Dehghani

Social media is an useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance. We study the problem of extraction of…

Information Retrieval · Computer Science 2017-09-07 Shashank Gupta , Sachin Pawar , Nitin Ramrakhiyani , Girish Palshikar , Vasudeva Varma

Early diagnosis of mental disorders and intervention can facilitate the prevention of severe injuries and the improvement of treatment results. Using social media and pre-trained language models, this study explores how user-generated data…

Information Retrieval · Computer Science 2024-03-01 Alireza Pourkeyvan , Ramin Safa , Ali Sorourkhah

In the field of medical imaging, the advent of deep learning, especially the application of convolutional neural networks (CNNs) has revolutionized the analysis and interpretation of medical images. Nevertheless, deep learning methods…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Xin Li , Wenhui Zhu , Peijie Qiu , Oana M. Dumitrascu , Amal Youssef , Yalin Wang

Automated depression diagnosis aims to analyze multimodal information from interview videos to predict participants' depression scores. Previous studies often lack clear explanations of how these scores were determined, limiting their…

Artificial Intelligence · Computer Science 2026-03-19 Wei Zhang , Juan Chen , En Zhu , Wenhong Cheng , YunPeng Li , Yanbo J. Wang

Electronic health records (EHR) contain narrative notes that provide extensive details on the medical condition and management of patients. Natural language processing (NLP) of clinical notes can use observed frequencies of clinical terms…

Computation and Language · Computer Science 2023-07-04 Bryan Cai , Sihang Zeng , Yucong Lin , Zheng Yuan , Doudou Zhou , Lu Tian

Emerging evidence showed that major depressive disorder (MDD) is associated with disruptions of brain structural and functional networks, rather than impairment of isolated brain region. Thus, connectome-based models capable of predicting…

Neurons and Cognition · Quantitative Biology 2021-10-18 Aya Kabbara , Gabriel Robert , Mohamad Khalil , Marc Verin , Pascal Benquet , Mahmoud Hassan

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

Clinical natural language processing (NLP) is increasingly in demand in both clinical research and operational practice. However, most of the state-of-the-art solutions are transformers-based and require high computational resources,…

Computation and Language · Computer Science 2025-04-18 Jianlin Shi , Qiwei Gan , Elizabeth Hanchrow , Annie Bowles , John Stanley , Adam P. Bress , Jordana B. Cohen , Patrick R. Alba
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