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In this paper we study the problem of predicting clinical diagnoses from textual Electronic Health Records (EHR) data. We show the importance of this problem in medical community and present comprehensive historical review of the problem…

Computation and Language · Computer Science 2020-09-29 Pavel Blinov , Manvel Avetisian , Vladimir Kokh , Dmitry Umerenkov , Alexander Tuzhilin

Clinical notes contain information about patients that goes beyond structured data like lab values and medications. However, clinical notes have been underused relative to structured data, because notes are high-dimensional and sparse. This…

Computation and Language · Computer Science 2020-12-01 Kexin Huang , Jaan Altosaar , Rajesh Ranganath

Depression is a prominent health challenge to the world, and early risk detection (ERD) of depression from online posts can be a promising technique for combating the threat. Early depression detection faces the challenge of efficiently…

Computation and Language · Computer Science 2022-05-20 Zhiling Zhang , Siyuan Chen , Mengyue Wu , Kenny Q. Zhu

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…

Computation and Language · Computer Science 2025-01-03 Kaushik Roy , Harshul Surana , Darssan Eswaramoorthi , Yuxin Zi , Vedant Palit , Ritvik Garimella , Amit Sheth

Background: Depression is a major public health concern, affecting an estimated five percent of the global population. Early and accurate diagnosis is essential to initiate effective treatment, yet recognition remains challenging in many…

Signal Processing · Electrical Eng. & Systems 2025-11-21 Jana Weber , Marcel Weber , Juan Miguel Lopez Alcaraz

Depression is a prevalent mental health disorder that is difficult to detect early due to subjective symptom assessments. Recent advancements in large language models have offered efficient and cost-effective approaches for this objective.…

Computation and Language · Computer Science 2025-04-08 Longdi Xian , Jianzhang Ni , Mingzhu Wang

Dementia is a neurological syndrome marked by cognitive decline. Alzheimer's disease (AD) and Frontotemporal dementia (FTD) are the common forms of dementia, each with distinct progression patterns. EEG, a non-invasive tool for recording…

Signal Processing · Electrical Eng. & Systems 2024-08-21 Shivani Ranjan , Ayush Tripathi , Harshal Shende , Robin Badal , Amit Kumar , Pramod Yadav , Deepak Joshi , Lalan Kumar

With large volumes of health care data comes the research area of computational phenotyping, making use of techniques such as machine learning to describe illnesses and other clinical concepts from the data itself. The "traditional"…

Machine Learning · Statistics 2016-12-30 Chris Hodapp

Large Language Models (LLMs) have demonstrated potential in predicting mental health outcomes from online text, yet traditional classification methods often lack interpretability and robustness. This study evaluates structured reasoning…

Computation and Language · Computer Science 2026-01-09 Avinash Patil , Amardeep Kour Gedhu

Pretraining large neural language models, such as BERT, has led to impressive gains on many natural language processing (NLP) tasks. However, most pretraining efforts focus on general domain corpora, such as newswire and Web. A prevailing…

Computation and Language · Computer Science 2021-09-20 Yu Gu , Robert Tinn , Hao Cheng , Michael Lucas , Naoto Usuyama , Xiaodong Liu , Tristan Naumann , Jianfeng Gao , Hoifung Poon

Deep neural networks have shown promising results for various clinical prediction tasks. However, training deep networks such as those based on Recurrent Neural Networks (RNNs) requires large labeled data, significant hyper-parameter tuning…

Machine Learning · Computer Science 2021-03-05 Priyanka Gupta , Pankaj Malhotra , Jyoti Narwariya , Lovekesh Vig , Gautam Shroff

Millions of people openly share mental health struggles on social media, providing rich data for early detection of conditions such as depression, bipolar disorder, etc. However, most prior Natural Language Processing (NLP) research has…

Computation and Language · Computer Science 2025-09-23 Khalid Hasan , Jamil Saquer , Yifan Zhang

We present a statistical model for German medical natural language processing trained for named entity recognition (NER) as an open, publicly available model. The work serves as a refined successor to our first GERNERMED model which is…

Computation and Language · Computer Science 2022-10-11 Johann Frei , Ludwig Frei-Stuber , Frank Kramer

Neurological conditions, such as Alzheimer's Disease, are challenging to diagnose, particularly in the early stages where symptoms closely resemble healthy controls. Existing brain network analysis methods primarily focus on graph-based…

Neurons and Cognition · Quantitative Biology 2025-05-20 Jiaxing Xu , Kai He , Yue Tang , Wei Li , Mengcheng Lan , Xia Dong , Yiping Ke , Mengling Feng

Background: The evolution of symptoms over time is at the heart of understanding and treating mental disorders. However, a principled, quantitative framework explaining symptom dynamics remains elusive. Here, we propose a Network Control…

Health sensing for chronic disease management creates immense benefits for social welfare. Existing health sensing studies primarily focus on the prediction of physical chronic diseases. Depression, a widespread complication of chronic…

Artificial Intelligence · Computer Science 2025-04-17 Jiaheng Xie , Xiaohang Zhao , Xiang Liu , Xiao Fang

Fine-tuned Bidirectional Encoder Representations from Transformers (BERT)-based sequence classification models have proven to be effective for detecting Alzheimer's Disease (AD) from transcripts of human speech. However, previous research…

Computation and Language · Computer Science 2020-11-13 Aparna Balagopalan , Jekaterina Novikova

Large pre-trained neural networks such as BERT have had great recent success in NLP, motivating a growing body of research investigating what aspects of language they are able to learn from unlabeled data. Most recent analysis has focused…

Computation and Language · Computer Science 2019-06-12 Kevin Clark , Urvashi Khandelwal , Omer Levy , Christopher D. Manning

The early detection of mental health disorders from social media text is critical for enabling timely support, risk assessment, and referral to appropriate resources. This work introduces multiMentalRoBERTa, a fine-tuned RoBERTa model…

Computation and Language · Computer Science 2025-11-11 K M Sajjadul Islam , John Fields , Praveen Madiraju

We aim to evaluate the efficacy of traditional machine learning and large language models (LLMs) in classifying anxiety and depression from long conversational transcripts. We fine-tune both established transformer models (BERT, RoBERTa,…

Computation and Language · Computer Science 2024-07-19 Junwei Sun , Siqi Ma , Yiran Fan , Peter Washington
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