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Related papers: Detecting cognitive decline using speech only: The…

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Early detection of dementia is very crucial to ensure treatment begins on time, however it is difficult to choose appropriate cognitive assessment tools because each test is designed differently and may not be tailored to the needs of a…

Quantitative Methods · Quantitative Biology 2025-05-13 Saransh Naole , Dhriti Parikh , Sakshi Nayak , Swarna Priya Ramu

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

Accurate prediction of clinical scores is critical for early detection and prognosis of Alzheimers disease (AD). While existing approaches primarily focus on forecasting the ADAS-Cog global score, they often overlook the predictive value of…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Nur Amirah Abd Hamid , Mohd Shahrizal Rusli , Muhammad Thaqif Iman Mohd Taufek , Mohd Ibrahim Shapiai , Daphne Teck Ching Lai

Depression commonly co-occurs with neurodegenerative disorders like Multiple Sclerosis (MS), yet the potential of speech-based Artificial Intelligence for detecting depression in such contexts remains unexplored. This study examines the…

Computation and Language · Computer Science 2025-08-26 Monica Gonzalez-Machorro , Uwe Reichel , Pascal Hecker , Helly Hammer , Hesam Sagha , Florian Eyben , Robert Hoepner , Björn W. Schuller

Automated speech analysis is a thriving approach to detect early markers of Alzheimer's disease (AD). Yet, recording conditions in most AD datasets are heterogeneous, with patients and controls often evaluated in different acoustic…

Early detection and treatment of depression is essential in promoting remission, preventing relapse, and reducing the emotional burden of the disease. Current diagnoses are primarily subjective, inconsistent across professionals, and…

Machine Learning · Computer Science 2020-02-03 Karol Chlasta , Krzysztof Wołk , Izabela Krejtz

Alzheimer's disease (AD) is the most common neurodegenerative disease in older people. Despite considerable efforts to find a cure for AD, there is a 99.6% failure rate of clinical trials for AD drugs, likely because AD patients cannot…

Machine Learning · Computer Science 2019-03-25 Jack Albright

Alzheimer's disease (AD) is a common form of dementia that severely impacts patient health. As AD impairs the patient's language understanding and expression ability, the speech of AD patients can serve as an indicator of this disease. This…

Audio and Speech Processing · Electrical Eng. & Systems 2023-07-07 Hongmin Cai , Xiaoke Huang , Zhengliang Liu , Wenxiong Liao , Haixing Dai , Zihao Wu , Dajiang Zhu , Hui Ren , Quanzheng Li , Tianming Liu , Xiang Li

Time-dependent data collected in studies of Alzheimer's disease usually has missing and irregularly sampled data points. For this reason time series methods which assume regular sampling cannot be applied directly to the data without a…

Quantitative Methods · Quantitative Biology 2019-03-06 Paul Moore , Terry Lyons , John Gallacher

The Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) is a neuropsychological tool that has been designed to assess the severity of cognitive symptoms of dementia. Personalized prediction of the changes in ADAS-Cog scores…

Machine Learning · Computer Science 2021-09-22 Vandad Imani , Mithilesh Prakash , Marzieh Zare , Jussi Tohka

The most frequent kind of dementia of the nervous system, Alzheimer's disease, weakens several brain processes (such as memory) and eventually results in death. The clinical study uses magnetic resonance imaging to diagnose AD. Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Sarasadat Foroughipoor , Kimia Moradi , Hamidreza Bolhasani

The rise of Alzheimers Disease worldwide has prompted a search for efficient tools which can be used to predict deterioration in cognitive decline leading to dementia. In this paper, we explore the potential of survival machine learning as…

Machine Learning · Computer Science 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

Dementia, a prevalent neurodegenerative condition, is a major manifestation of Alzheimer's disease (AD). As the condition progresses from mild to severe, it significantly impairs the individual's ability to perform daily tasks…

Machine Learning · Computer Science 2023-11-06 Md Gulzar Hussain , Ye Shiren

Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Weichen Huang

Multiple modalities of biomarkers have been proved to be very sensitive in assessing the progression of Alzheimer's disease (AD), and using these modalities and machine learning algorithms, several approaches have been proposed to assist in…

Machine Learning · Statistics 2017-12-05 Chen Fang , Panuwat Janwattanapong , Chunfei Li , Malek Adjouadi

Dementia diagnosis requires a series of different testing methods, which is complex and time-consuming. Early detection of dementia is crucial as it can prevent further deterioration of the condition. This paper utilizes a speech…

Computation and Language · Computer Science 2023-12-18 Zih-Jyun Lin , Yi-Ju Chen , Po-Chih Kuo , Likai Huang , Chaur-Jong Hu , Cheng-Yu Chen

Cognition in midlife is an important predictor of age-related mental decline and statistical models that predict cognitive performance can be useful for predicting decline. However, existing models struggle to capture complex relationships…

Machine Learning · Computer Science 2021-12-30 Sharath Koorathota , Arunesh Mittal , Richard P. Sloan , Paul Sajda

Most approaches to machine learning from electronic health data can only predict a single endpoint. Here, we present an alternative that uses unsupervised deep learning to simulate detailed patient trajectories. We use data comprising…

Machine Learning · Computer Science 2019-10-10 Charles K. Fisher , Aaron M. Smith , Jonathan R. Walsh , the Coalition Against Major Diseases

Nowadays, due to tremendous improvements in high performance computing, it has become easier to train Neural Networks. We intend to take advantage of this situation and apply this technology in solving real world problems. There was a need…

Computer Vision and Pattern Recognition · Computer Science 2019-10-15 Gururaj Awate , Sunil Bangare , G Pradeepini , S Patil

Alzheimer`s disease (AD)-related global healthcare cost is estimated to be $1 trillion by 2050. Currently, there is no cure for this disease; however, clinical studies show that early diagnosis and intervention helps to extend the quality…

Computers and Society · Computer Science 2020-05-27 Ning Wang , Fan Luo , Vishal Peddagangireddy , K. P. Subbalakshmi , R. Chandramouli