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Alzheimers disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimers disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8 to 4.4 years after…

Accurately detecting Alzheimer's disease (AD) and predicting mini-mental state examination (MMSE) score are important tasks in elderly health by magnetic resonance imaging (MRI). Most of the previous methods on these two tasks are based on…

Image and Video Processing · Electrical Eng. & Systems 2023-07-10 Xu Tian , Jin Liu , Hulin Kuang , Yu Sheng , Jianxin Wang , The Alzheimer's Disease Neuroimaging Initiative

Alzheimer's disease is a common cognitive disorder in the elderly. Early and accurate diagnosis of Alzheimer's disease (AD) has a major impact on the progress of research on dementia. At present, researchers have used machine learning…

Sound · Computer Science 2024-02-20 Xiaohui Zhang , Wenjie Fu , Mangui Liang

With populations ageing, the number of people with dementia worldwide is expected to triple to 152 million by 2050. Seventy percent of cases are due to Alzheimer's disease (AD) pathology and there is a 10-20 year 'pre-clinical' period…

Artificial Intelligence · Computer Science 2021-04-30 Renjie Li , Xinyi Wang , Katherine Lawler , Saurabh Garg , Quan Bai , Jane Alty

Alzheimer's dementia (AD) affects memory, thinking, and language, deteriorating person's life. An early diagnosis is very important as it enables the person to receive medical help and ensure quality of life. Therefore, leveraging…

Machine Learning · Computer Science 2023-04-06 Michail Chatzianastasis , Loukas Ilias , Dimitris Askounis , Michalis Vazirgiannis

Speech is usually used for constructing an automatic Alzheimer's dementia (AD) detection system, as the acoustic and linguistic abilities show a decline in people living with AD at the early stages. However, speech includes not only…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-11 Yilin Pan , Yanpei Shi , Yijia Zhang , Mingyu Lu

Aphasia is a language disorder that affects the speaking ability of millions of patients. This paper presents a new benchmark for Aphasia speech recognition and detection tasks using state-of-the-art speech recognition techniques with the…

Audio and Speech Processing · Electrical Eng. & Systems 2023-05-24 Jiyang Tang , William Chen , Xuankai Chang , Shinji Watanabe , Brian MacWhinney

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…

Signal Processing · Electrical Eng. & Systems 2024-04-02 Arezoo Borji , Taha-Hossein Hejazi , Abbas Seifi

Over half of US adults with Alzheimer disease and related dementias remain undiagnosed, and speech-based screening offers a scalable detection approach. We compared large language model adaptation strategies for dementia detection using the…

Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Hongming Li , Mohamad Habes , David A. Wolk , Yong Fan

Alzheimer's disease (AD) is a progressive brain disorder that causes memory and functional impairments. The advances in machine learning and publicly available medical datasets initiated multiple studies in AD diagnosis. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Aidana Massalimova , Huseyin Atakan Varol

Amyotrophic lateral sclerosis is a fatal disease that not only affects movement, speech, and breath but also cognition. Recent studies have focused on the use of language analysis techniques to detect ALS and infer scales for monitoring…

Computation and Language · Computer Science 2023-09-14 Carla Agurto , Guillermo Cecchi , Bo Wen , Ernest Fraenkel , James Berry , Indu Navar , Raquel Norel

Early diagnosis of Alzheimer's Disease (AD) is crucial for delaying its progression. While AI-based speech detection is non-invasive and cost-effective, it faces a critical data efficiency dilemma due to medical data scarcity and privacy…

Computation and Language · Computer Science 2026-02-17 Xiao Wei , Bin Wen , Yuqin Lin , Kai Li , Mingyang gu , Xiaobao Wang , Longbiao Wang , Jianwu Dang

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the…

Computation and Language · Computer Science 2021-02-25 Swati Padhee , Anurag Illendula , Megan Sadler , Valerie L. Shalin , Tanvi Banerjee , Krishnaprasad Thirunarayan , William L. Romine

Alzheimer's disease (AD) stands as the predominant cause of dementia, characterized by a gradual decline in speech and language capabilities. Recent deep-learning advancements have facilitated automated AD detection through spontaneous…

Computation and Language · Computer Science 2024-09-20 Chin-Po Chen , Jeng-Lin Li

INTRODUCTION: Heterogeneity in the progression of Alzheimer's disease makes it challenging to predict the rate of cognitive and functional decline for individual patients. Tools for short-term prediction could help enrich clinical trial…

Quantitative Methods · Quantitative Biology 2021-01-22 Neda Shafiee , Mahsa Dadar , Simon Ducharme , D. Louis Collins

Alzheimer's disease (AD) is known as one of the major causes of dementia and is characterized by slow progression over several years, with no treatments or available medicines. In this regard, there have been efforts to identify the risk of…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Wonsik Jung , Eunji Jun , Heung-Il Suk

We present the findings of "The Alzheimer's Disease Prediction Of Longitudinal Evolution" (TADPOLE) Challenge, which compared the performance of 92 algorithms from 33 international teams at predicting the future trajectory of 219…

Populations and Evolution · Quantitative Biology 2021-12-30 Razvan V. Marinescu , Neil P. Oxtoby , Alexandra L. Young , Esther E. Bron , Arthur W. Toga , Michael W. Weiner , Frederik Barkhof , Nick C. Fox , Arman Eshaghi , Tina Toni , Marcin Salaterski , Veronika Lunina , Manon Ansart , Stanley Durrleman , Pascal Lu , Samuel Iddi , Dan Li , Wesley K. Thompson , Michael C. Donohue , Aviv Nahon , Yarden Levy , Dan Halbersberg , Mariya Cohen , Huiling Liao , Tengfei Li , Kaixian Yu , Hongtu Zhu , Jose G. Tamez-Pena , Aya Ismail , Timothy Wood , Hector Corrada Bravo , Minh Nguyen , Nanbo Sun , Jiashi Feng , B. T. Thomas Yeo , Gang Chen , Ke Qi , Shiyang Chen , Deqiang Qiu , Ionut Buciuman , Alex Kelner , Raluca Pop , Denisa Rimocea , Mostafa M. Ghazi , Mads Nielsen , Sebastien Ourselin , Lauge Sorensen , Vikram Venkatraghavan , Keli Liu , Christina Rabe , Paul Manser , Steven M. Hill , James Howlett , Zhiyue Huang , Steven Kiddle , Sach Mukherjee , Anais Rouanet , Bernd Taschler , Brian D. M. Tom , Simon R. White , Noel Faux , Suman Sedai , Javier de Velasco Oriol , Edgar E. V. Clemente , Karol Estrada , Leon Aksman , Andre Altmann , Cynthia M. Stonnington , Yalin Wang , Jianfeng Wu , Vivek Devadas , Clementine Fourrier , Lars Lau Raket , Aristeidis Sotiras , Guray Erus , Jimit Doshi , Christos Davatzikos , Jacob Vogel , Andrew Doyle , Angela Tam , Alex Diaz-Papkovich , Emmanuel Jammeh , Igor Koval , Paul Moore , Terry J. Lyons , John Gallacher , Jussi Tohka , Robert Ciszek , Bruno Jedynak , Kruti Pandya , Murat Bilgel , William Engels , Joseph Cole , Polina Golland , Stefan Klein , Daniel C. Alexander

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that progressively impairs memory, decision-making, and overall cognitive function. As AD is irreversible, early prediction is critical for timely intervention and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Mahdieh Behjat Khatooni , Mohsen Soryani

Automatic Speech Recognition (ASR) is a critical component of any fully-automated speech-based dementia detection model. However, despite years of speech recognition research, little is known about the impact of ASR accuracy on dementia…

Computation and Language · Computer Science 2020-10-15 Aparna Balagopalan , Ksenia Shkaruta , Jekaterina Novikova
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