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Spatial Frequency Domain Imaging can map tissue scattering and absorption properties over a wide field of view, making it useful for clinical applications such as wound assessment and surgical guidance. This technique has previously…

Biological Physics · Physics 2021-02-24 Mason T. Chen , Melina Papadakis , Nicholas J. Durr

Mid-infrared spectroscopy offers powerful label-free molecular analysis capabilities but faces significant challenges when analyzing complex biological samples. Here, we present a transformative surface-enhanced infrared absorption…

High-quality panoramic images with a Field of View (FoV) of 360{\deg} are essential for contemporary panoramic computer vision tasks. However, conventional imaging systems come with sophisticated lens designs and heavy optical components.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Qi Jiang , Shaohua Gao , Yao Gao , Kailun Yang , Zhonghua Yi , Hao Shi , Lei Sun , Kaiwei Wang

Using a deep neural network, we demonstrate a digital staining technique, which we term PhaseStain, to transform quantitative phase images (QPI) of labelfree tissue sections into images that are equivalent to brightfield microscopy images…

Image and Video Processing · Electrical Eng. & Systems 2019-02-08 Yair Rivenson , Tairan Liu , Zhensong Wei , Yibo Zhang , Aydogan Ozcan

Single-pixel imaging (SPI) exhibits cost-effectiveness, broad spectrum, and stable sub-Nyquist sampling reconstruction, enabling applications across diverse imaging fields.However, due to the inherent reconstruction mechanism, SPI is not…

Optics · Physics 2025-04-18 Shao Chongwu , Cao Yue , Zhao Qing , Yao Xuri

Single Pixel (SP) imaging is now a reality in many applications, e.g., biomedical ultrathin endoscope and fluorescent spectroscopy. In this context, many schemes exist to improve the light throughput of these device, e.g., using structured…

Computer Vision and Pattern Recognition · Computer Science 2019-02-19 Amirafshar Moshtaghpour , José M. Bioucas-Dias , Laurent Jacques

We propose a novel technique of microscopy to overcome the effects of both scattering and limitation of the accessible depth due to the objective working distance. By combining Laser Optical Feedback Imaging (LOFI) with Acoustic Photon…

Over the past decade, structured illumination microscopy (SIM) has found its niche in super-resolution (SR) microscopy due to its fast imaging speed and low excitation intensity. However, due to the significantly higher light dose compared…

Transient imaging or light-in-flight techniques capture the propagation of an ultra-short pulse of light through a scene, which in effect captures the optical impulse response of the scene. Recently, it has been shown that we can capture…

Computer Vision and Pattern Recognition · Computer Science 2015-12-22 Ryuichi Tadano , Adithya Kumar Pediredla , Kaushik Mitra , Ashok Veeraraghavan

Computational imaging methods empower modern microscopy with the ability of producing high-resolution, large field-of-view, aberration-free images. One of the dominant computational label-free imaging methods, Fourier ptychographic…

Optics · Physics 2023-09-06 Ruizhi Cao , Cheng Shen , Changhuei Yang

We introduce a single-frame diffractive imaging method called randomized probe imaging (RPI). In RPI, a sample is illuminated by a structured probe field containing speckles smaller than the sample's typical feature size. Quantitative…

Molecular dipoles near interfaces emit highly directional radiation due to near-field interactions, making surface-bound fluorophores sensitive probes of local physicochemical changes. We introduce smart coverslips, stably coated with…

The classically defined minimum uncertainty of the optical phase is known as the standard quantum limit or shot-noise limit (SNL) originating in the uncertainty principle of quantum mechanics. Based on SNL, the phase sensitivity is…

Quantum Physics · Physics 2024-05-29 Byoung S. Ham

Complex-field imaging is indispensable for numerous applications at wavelengths from X-ray to THz, with amplitude describing transmittance (or reflectivity) and phase revealing intrinsic structure of the target object. Coherent diffraction…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Meng Li , Liheng Bian , Guoan Zheng , Andrew Maiden , Yang Liu , Yiming Li , Qionghai Dai , Jun Zhang

We present a high-precision temporal-spatial phase-demodulation algorithm for phase-shifting interferometry (PSI) affected by random/systematic phase-stepping errors. Laser interferometers in standard optical-shops suffer from several error…

Signal Processing · Electrical Eng. & Systems 2019-12-11 Manuel Servin , Moises Padilla , Guillermo Garnica , Gonzalo Paez

The development of advanced packaging is essential in the semiconductor manufacturing industry. However, non-destructive testing (NDT) of advanced packaging becomes increasingly challenging due to the depth and complexity of the layers…

Instrumentation and Detectors · Physics 2025-07-17 J. Senthilnath , Jayasanker Jayabalan , Zhuoyi Lin , Aye Phyu Phyu Aung , Chen Hao , Kaixin Xu , Yeow Kheng Lim , F. C. Wellstood

Image simulation remains under-exploited for the most widely used biological phase microscopy methods, because of difficulties in simulating partially coherent illumination. We describe an open-source toolbox, microlith…

Optics · Physics 2014-05-14 Shalin B. Mehta , Rudolf Oldenbourg

Synthetic aperture imaging systems achieve constant azimuth resolution by coherently summating the observations acquired along the aperture path. At this aim, their locations have to be known with subwavelength accuracy. In underwater…

Systems and Control · Computer Science 2017-07-27 Salvatore Caporale , Yvan Petillot

We demonstrate a motion-free intensity diffraction tomography technique that enables direct inversion of 3D phase and absorption from intensity-only measurements for weakly scattering samples. We derive a novel linear forward model,…

Image and Video Processing · Electrical Eng. & Systems 2018-06-26 Ruilong Ling , Waleed Tahir , Hsing-Ying Lin , Hakho Lee , Lei Tian

Mid-infrared photothermal (MIP) microscopy has been a promising label-free chemical imaging technique for functional characterization of specimens owing to its enhanced spatial resolution and high specificity. Recently developed wide-field…