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For biologically relevant macromolecules such as intrinsically disordered proteins, internal degrees of freedom that allow for shape changes have a large influence on both the motion and function of the compound. A detailed understanding of…

The existence of travelling waves for a model of concentration waves of bacteria is investigated. The model consists in a kinetic equation for the biased motion of cells following a run-and-tumble process, coupled with two…

Analysis of PDEs · Mathematics 2016-07-05 Vincent Calvez

Important cellular processes, such as cell motility and cell division, are coordinated by cell polarity, which is determined by the non-uniform distribution of certain proteins. Such protein patterns form via an interplay of protein…

Biological Physics · Physics 2020-05-20 Manon C Wigbers , Fridtjof Brauns , Ching Yee Leung , Erwin Frey

Nuclei import and export proteins, including cell cycle regulators. These import-export processes are modulated periodically by the cell cycle, for example due to the periodic assembly and breakdown of the nuclear envelope. As such,…

Biological Physics · Physics 2021-06-30 Felix E. Nolet , Lendert Gelens

The dynamics of phase-separated interfaces shape the behavior of both passive and active condensates. While surface tension in equilibrium systems minimizes interface length, non-equilibrium fluxes can destabilize flat or constantly curved…

Soft Condensed Matter · Physics 2025-05-27 Florian Raßhofer , Simon Bauer , Alexander Ziepke , Ivan Maryshev , Erwin Frey

Biomolecular condensates play a crucial role in the spatial organization of living matter. These membrane-less organelles, resulting from liquid-liquid phase separation, operate far from thermodynamic equilibrium, with their size and…

Soft Condensed Matter · Physics 2025-05-12 Jacques Fries , Roxanne Berthin , Marie Jardat , Pierre Illien , Vincent Dahirel

Spiral waves are striking self-organized coherent structures that organize spatio-temporal dynamics in dissipative, spatially extended systems. In this paper, we provide a conceptual approach to various properties of spiral waves. Rather…

Pattern Formation and Solitons · Physics 2021-02-09 Björn Sandstede , Arnd Scheel

The persistent dynamics of active particles makes them explore extended portions of an obstacle's boundary during collisions. From impact to escape, the net applied forces depend on the curvature of the wall and increase in the presence of…

It is shown that information transmission inside a cell can occur by means of mechanical waves transmitted through DNA. The propagation of the waves is strongly dependent on the shape of the DNA thus proteins that change the shape of DNA…

Biological Physics · Physics 2007-05-23 Thomas C. Bishop , Oleksandr O. Zhmudsky

Plasma membrane tubes are ubiquitous in cellular membranes and in the membranes of intracellular organelles. They play crucial roles in trafficking, ion transport, and cellular motility. The formation of plasma membrane tubes can be due to…

Soft Condensed Matter · Physics 2022-06-09 Arijit Mahapatra , Padmini Rangamani

Myxobacteria are social bacteria, that can glide in 2D and form counter-propagating, interacting waves. Here we present a novel age-structured, continuous macroscopic model for the movement of myxobacteria. The derivation is based on…

Cell Behavior · Quantitative Biology 2018-04-06 Pierre Degond , Angelika Manhart , Hui Yu

In absence of advection, reaction-diffusion systems are able to organize into spatiotemporal patterns, in particular spiral and target waves. Whenever advection is present and can be parameterised in terms of effective or turbulent…

Fluid Dynamics · Physics 2012-12-10 A. von Kameke , F. Huhn , A. P. Muñuzuri , V. Pérez-Muñuzuri

Biomolecules, such as proteins and RNAs, can phase separate in the cytoplasm of cells to form biomolecular condensates. Such condensates are liquid-like droplets that can wet biological surfaces such as membranes. Many molecules that…

Soft Condensed Matter · Physics 2024-09-04 Xueping Zhao , Susanne Liese , Alf Honigmann , Frank Jülicher , Christoph A. Weber

Vesicle-mediated secretion of ions or molecules is a central mechanism of cellular communication, for example in processes such as neurotransmission or hormone release. These events are inherently stochastic: vesicle fusions lead to bursts…

Statistical Mechanics · Physics 2026-05-08 Jan Hauke , Julian B. Voits , Ulrich S. Schwarz

Motile and driven particles confined in microfluidic channels exhibit interesting emergent behavior from propagating density bands to density shock waves. A deeper understanding of the physical mechanisms responsible for these emergent…

Fluid Dynamics · Physics 2016-02-03 Alan Cheng Hou Tsang , Eva Kanso

This study explores experimentally the turbulent flow in a laboratory flume, interacting with waves propagated against the flow. It focuses a region of wave-blocking for which there is a streamwise location on the water surface, where the…

Fluid Dynamics · Physics 2018-04-18 Debasmita Chatterjee , B. S. Mazumder , Subir Ghosh

We investigate the oscillatory dynamics and bifurcation structure of a reaction-diffusion system with bistable nonlinearity and mass conservation, which was proposed by [Otsuji et al, PLoS Comp. Biol. 3 (2007), e108]. The system is a useful…

Cell Behavior · Quantitative Biology 2025-05-23 Masataka Kuwamura , Hirofumi Izuhara , Shin-ichiro Ei

We consider a system of two reaction-diffusion-advection equations describing the one dimensional directed motion of particles with superimposed diffusion and mutual alignment. For this system we show the existence of traveling wave…

Analysis of PDEs · Mathematics 2021-01-19 Heinrich Freistühler , Jan Fuhrmann

Biological adhesion is a critical mechanical function of complex organisms operating at multiple scales. At the cellular scale, cell-cell adhesion is remarkably tunable to enable both cohesion and malleability during development,…

Soft Condensed Matter · Physics 2022-03-07 Dimitri Kaurin , Pradeep K. Bal , Marino Arroyo

Scientists have observed and studied diffusive waves in contexts as disparate as population genetics and cell signaling. Often, these waves are propagated by discrete entities or agents, such as individual cells in the case of cell…

Pattern Formation and Solitons · Physics 2021-07-21 Paul Dieterle , Ariel Amir