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We investigate diffusion-limited reactions between a diffusing particle and a target site on a semiflexible polymer, a key factor determining the kinetics of DNA-protein binding and polymerization of cytoskeletal filaments. Our theory…

Soft Condensed Matter · Physics 2010-12-08 Yann von Hansen , Roland R. Netz , Michael Hinczewski

We develop theory and computational methods to investigate particle inclusions embedded within curved lipid bilayer membranes. We consider the case of spherical lipid vesicles where inclusion particles are coupled through (i) intramembrane…

Soft Condensed Matter · Physics 2023-02-28 Jon Karl Sigurdsson , Paul J. Atzberger

The structure of spiral waves is investigated in super-excitable reaction-diffusion systems where the local dynamics exhibits multi-looped phase space trajectories. It is shown that such systems support stable spiral waves with broken…

chao-dyn · Physics 2015-06-24 Andrei Goryachev , Raymond Kapral

Demixing of binary fluids subjected to slow temperature ramps shows repeated waves of nucleation which arise as a consequence of the competition between generation of supersaturation by the temperature ramp and relaxation of supersaturation…

Statistical Mechanics · Physics 2012-10-16 Izabella J. Benczik , Jürgen Vollmer

The effect of conformational fluctuations of modular macromolecules, such as enzymes, on their diffusion properties is addressed using a simple generic model of an asymmetric dumbbell made of two hydrodynamically coupled subunits. It is…

Soft Condensed Matter · Physics 2017-11-22 Pierre Illien , Tunrayo Adeleke-Larodo , Ramin Golestanian

An inhomogeneous profile of chemostatted species generates a rich variety of patterns in glycolytic waves depicted in a Selkov reaction-diffusion framework here. A key role played by diffusion amplitude and symmetry in the chemostatted…

Adaptation and Self-Organizing Systems · Physics 2022-12-20 Premashis Kumar , Gautam Gangopadhyay

Intracellular protein patterns regulate many vital cellular functions, such as the processing of spatiotemporal information or the control of shape deformations. To do so, pattern-forming systems can be sensitive to the cell geometry by…

Biological Physics · Physics 2024-05-15 Tom Burkart , Benedikt J. Müller , Erwin Frey

Recent experiments have revealed that the meniscus formed near a surface-piercing barrier can significantly alter the propagation and scattering of capillary-gravity surface waves, beyond what classic flat-surface models predict. In…

Fluid Dynamics · Physics 2025-04-17 Guoqin Liu , Zhengwu Wang , Likun Zhang

For natural microswimmers, the interplay of swimming activity and external flow can promote robust motion, e.g. propulsion against ("upstream rheotaxis") or perpendicular to the direction of flow. These effects are generally attributed to…

Soft Condensed Matter · Physics 2018-01-30 Jaideep Katuri , William E. Uspal , Juliane Simmchen , Albert Miguel-López , Samuel Sánchez

The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, although a comprehensive theory of biological pattern formation is still lacking. Here, we propose a minimal model combining tissue mechanics…

Biological Physics · Physics 2022-06-08 P. Recho , A. Hallou , E. Hannezo

Surface curvature of magnetic systems can lead to many static and dynamic effects which are not present in flat systems of the same material. These emergent magnetochiral effects can lead to frequency nonreciprocity of spin waves, which has…

Mesoscale and Nanoscale Physics · Physics 2022-07-20 Lukas Körber , Roman Verba , Jorge A. Otálora , Volodymyr Kravchuk , Jürgen Lindner , Jürgen Fassbender , Attila Kákay

Many cell functions require a concerted effort from multiple membrane proteins, for example, for signaling, cell division, and endocytosis. One contribution to their successful self-organization stems from the membrane deformations that…

Soft Condensed Matter · Physics 2023-06-21 Ali Azadbakht , Billie Meadowcroft , Juraj Májek , Anđela Šarić , Daniela J. Kraft

Diffusion-mediated surface phenomena are crucial for human life and industry, with examples ranging from oxygen capture by lung alveolar surface to heterogeneous catalysis, gene regulation, membrane permeation and filtration processes.…

Statistical Mechanics · Physics 2020-08-19 Denis S. Grebenkov

Membrane tubulation is a ubiquitous process that occurs both at the plasma membrane and on the membranes of intracellular organelles. These tubulation events are known to be mediated by forces applied on the membrane either due to motor…

Soft Condensed Matter · Physics 2020-12-03 Arijit Mahapatra , Can Uysalel , Padmini Rangamani

The effect of curvature and how it induces and enhances the transport of colloidal particles driven through narrow channels represent an unexplored research avenue. Here we combine experiments and simulations to investigate the dynamics of…

In many biological systems, the movement of individual agents is commonly characterized as having multiple qualitatively distinct behaviors that arise from various biophysical states. This is true for vesicles in intracellular transport,…

Subcellular Processes · Quantitative Biology 2022-07-25 Maria-Veronica Ciocanel , John Fricks , Peter R. Kramer , Scott A. McKinley

We present spatio-temporal characteristics of spreading depolarizations (SD) in two experimental systems: retracting SD wave segments observed with intrinsic optical signals in chicken retina, and spontaneously occurring re-entrant SD waves…

The function of membrane-embedded proteins such as ion channels depends crucially on their conformation. We demonstrate how conformational changes in asymmetric membrane proteins may be inferred from measurements of their diffusion. Such…

Soft Condensed Matter · Physics 2015-11-20 Richard G. Morris , Matthew S. Turner

The transport of particles across lipid-bilayer membranes is important for biological cells to exchange information and material with their environment. Large particles often get wrapped by membranes, a process which has been intensively…

Soft Condensed Matter · Physics 2024-06-04 Jiarul Midya , Thorsten Auth , Gerhard Gompper

Recent advancements in the ability to construct three-dimensional (3D) tissues and organoids from stem cells and biomaterials have not only opened abundant new research avenues in disease modeling and regenerative medicine but also have…

Tissues and Organs · Quantitative Biology 2017-07-27 Richard J. McMurtrey