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The human body consists of microbiomes associated with the development and prevention of several diseases. These microbial organisms form several complex interactions that are informative to the scientific community for explaining disease…

Methodology · Statistics 2024-04-16 Tejasv Bedi , Bencong Zhu , Michael L. Neugent , Kevin C. Lutz , Nicole J. De Nisco , Qiwei Li

Mutual information (MI) is one of the most general ways to measure relationships between random variables, but estimating this quantity for complex systems is challenging. Denoising diffusion models have recently set a new bar for density…

Machine Learning · Computer Science 2025-11-20 Longxuan Yu , Xing Shi , Xianghao Kong , Tong Jia , Greg Ver Steeg

In the classical contamination models, such as the gross-error (Huber and Tukey contamination model or Case-wise Contamination), observations are considered as the units to be identified as outliers or not. This model is very useful when…

Statistics Theory · Mathematics 2021-03-11 Giovanni Saraceno , Claudio Agostinelli

Feature selection, which searches for the most representative features in observed data, is critical for health data analysis. Unlike feature extraction, such as PCA and autoencoder based methods, feature selection preserves…

Machine Learning · Computer Science 2018-12-04 Shiyu Liu , Mehul Motani

Optical microscopy contributes to the ever-increasing progress in biological and biomedical studies, as it allows the implementation of minimally invasive experimental pipelines to translate the data of measured samples into valuable…

Quantitative Methods · Quantitative Biology 2025-04-03 Elena Corbetta , Thomas Bocklitz

This paper introduces a novel iterative method for missing data imputation that sequentially reduces the mutual information between data and the corresponding missingness mask. Inspired by GAN-based approaches that train generators to…

Machine Learning · Statistics 2025-11-26 Jiahao Yu , Qizhen Ying , Leyang Wang , Ziyue Jiang , Song Liu

Social relationships can be divided into different classes based on the regularity with which they occur and the similarity among them. Thus, rare and somewhat similar relationships are random and cause noise in a social network, thus…

Social and Information Networks · Computer Science 2018-10-08 Jeancarlo Campos Leão , Michele Amaral Brandão , Pedro O. S. Vaz de Melo , Alberto H. F. Laender

Motivation: Clustering is a frequently used concept in variety of bioinformatical applications. We present a new method for hierarchical clustering of data called mutual information clustering (MIC) algorithm. It uses mutual information…

Quantitative Methods · Quantitative Biology 2007-05-23 Alexander Kraskov , Harald Stögbauer , Ralph G. Andrzejak , Peter Grassberger

Various types of promising techniques have come into being for influence maximization whose aim is to identify influential nodes in complex networks. In essence, real-world applications usually have high requirements on the balance between…

Social and Information Networks · Computer Science 2024-09-24 Yi Liu , Xiaoan Tang , Witold Pedrycz , Qiang Zhang

Analysis of microscopy images is one important tool in many fields of biomedical research, as it allows the quantification of a multitude of parameters at the cellular level. However, manual counting of these images is both tiring and…

Computer Vision and Pattern Recognition · Computer Science 2013-11-13 P. A Nogueira

The increasing volumes of data produced by high-throughput instruments coupled with advanced computational infrastructures for scientific computing have enabled what is often called a {\em Fourth Paradigm} for scientific research based on…

Relational data augmentation is a powerful technique for enhancing data analytics and improving machine learning models by incorporating columns from external datasets. However, it is challenging to efficiently discover relevant external…

Databases · Computer Science 2025-03-06 Aécio Santos , Flip Korn , Juliana Freire

Learning-based hashing methods are widely used for nearest neighbor retrieval, and recently, online hashing methods have demonstrated good performance-complexity trade-offs by learning hash functions from streaming data. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Fatih Cakir , Kun He , Sarah Adel Bargal , Stan Sclaroff

Statistical quality control in semiconductor manufacturing hinges on effective diagnostics of wafer bin maps, wherein a key challenge is to detect how defective chips tend to spatially cluster on a wafer--a problem known as spatial pattern…

Applications · Statistics 2021-03-01 Ahmed Aziz Ezzat , Sheng Liu , Dorit S. Hochbaum , Yu Ding

In microbial ecology studies, the most commonly used ways of investigating alpha (within-sample) diversity are either to apply count-only measures such as Simpson's index to Operational Taxonomic Unit (OTU) groupings, or to use classical…

Populations and Evolution · Quantitative Biology 2013-05-03 Connor O. McCoy , Frederick A. Matsen

High throughput sequencing (HTS) continues to expand our understanding of microbial communities, despite insufficient sequencing depths to detect all rare taxa. These low abundance taxa are not accounted for in existing methods for…

Applications · Statistics 2016-05-10 Amy Willis , John Bunge , Thea Whitman

In this paper, we proposed a novel two-stage optimization method for network community partition, which is based on inherent network structure information. The introduced optimization approach utilizes the new network centrality measure of…

Social and Information Networks · Computer Science 2019-07-16 Yiguang Bai , Sanyang Liu , Ke Yin , Jing Yuan

Percolation based graph matching algorithms rely on the availability of seed vertex pairs as side information to efficiently match users across networks. Although such algorithms work well in practice, there are other types of side…

Social and Information Networks · Computer Science 2017-06-22 Kushagra Singhal , Daniel Cullina , Negar Kiyavash

Recent advances in next-generation sequencing have revolutionized genomic research. 16S rRNA amplicon sequencing using paired-end sequencing on the MiSeq platform from Illumina, Inc., is being used to characterize the composition and…

Genomics · Quantitative Biology 2015-12-11 Hardik I. Parikh , Vishal N. Koparde , Steven P. Bradley , Gregory A. Buck , Nihar U. Sheth

In the past few decades, researchers have proposed many discriminant analysis (DA) algorithms for the study of high-dimensional data in a variety of problems. Most DA algorithms for feature extraction are based on transformations that…

Computer Vision and Pattern Recognition · Computer Science 2012-06-12 Ali Shadvar