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Robustness and generalizability in medical image segmentation are often hindered by scarcity and limited diversity of training data, which stands in contrast to the variability encountered during inference. While conventional strategies --…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Yimu Pan , Sitao Zhang , Alison D. Gernand , Jeffery A. Goldstein , James Z. Wang

Staining reveals the micro structure of the aspirate while creating histopathology slides. Stain variation, defined as a chromatic difference between the source and the target, is caused by varying characteristics during staining, resulting…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Nilanjan Chattopadhyay , Shiv Gehlot , Nitin Singhal

We propose a two-step domain shift-invariant mitosis cell detection method based on Faster RCNN and a convolutional neural network (CNN). We generate various domain-shifted versions of existing histopathology images using a stain…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Ramin Nateghi , Fattaneh Pourakpour

Self-supervised blind denoising for Poisson-Gaussian noise remains a challenging task. Pseudo-supervised pairs constructed from single noisy images re-corrupt the signal and degrade the performance. The visible blindspots solve the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Zejin Wang , Jiazheng Liu , Hao Zhai , Hua Han

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

This paper introduces a Virtual Immunohistochemistry Multiplex staining (VIMs) model designed to generate multiple immunohistochemistry (IHC) stains from a single hematoxylin and eosin (H&E) stained tissue section. IHC stains are crucial in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Shikha Dubey , Yosep Chong , Beatrice Knudsen , Shireen Y. Elhabian

Immunohistochemical (IHC) virtual staining is a task that generates virtual IHC images from H\&E images while maintaining pathological semantic consistency with adjacent slices. This task aims to achieve cross-domain mapping between…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Yue Peng , Bing Xiong , Fuqiang Chen , De Eybo , RanRan Zhang , Wanming Hu , Jing Cai , Wenjian Qin

Diffusion-weighted magnetic resonance imaging (DWI) is the only noninvasive method for quantifying microstructure and reconstructing white-matter pathways in the living human brain. Fluctuations from multiple sources create significant…

Machine Learning · Computer Science 2020-11-04 Shreyas Fadnavis , Joshua Batson , Eleftherios Garyfallidis

Raman spectroscopy can provide insight into the molecular composition of cells and tissue. Consequently, it can be used as a powerful diagnostic tool, e.g. to help identify changes in molecular contents with the onset of disease. But robust…

Medical Physics · Physics 2023-08-02 Ciaran Bench , Mads S. Bergholt , Mohamed Ali al-Badri

Mixup augmentation has been widely integrated to generate adversarial examples with superior adversarial transferability when immigrating from a surrogate model to other models. However, the underlying mechanism influencing the mixup's…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Xiaosen Wang , Zeyuan Yin

Data imbalance is a major problem that affects several machine learning (ML) algorithms. Such a problem is troublesome because most of the ML algorithms attempt to optimize a loss function that does not take into account the data imbalance.…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Steve Tsham Mpinda Ataky , Jonathan de Matos , Alceu de S. Britto , Luiz E. S. Oliveira , Alessandro L. Koerich

Virtual staining has emerged as a powerful alternative to traditional histopathological staining techniques, enabling rapid, reagent-free image transformations. However, existing evaluation methods predominantly rely on full-reference image…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Qiankai Wang , James E. D. Tweel , Parsin Haji Reza , Anita Layton

Adversarial attacks find perturbations that can fool models into misclassifying images. Previous works had successes in generating noisy/edge-rich adversarial perturbations, at the cost of degradation of image quality. Such perturbations,…

Computer Vision and Pattern Recognition · Computer Science 2018-08-09 Wen Heng , Shuchang Zhou , Tingting Jiang

Cycle reconstruction regularized adversarial training -- e.g., CycleGAN, DiscoGAN, and DualGAN -- has been widely used for image style transfer with unpaired training data. Several recent works, however, have shown that local distortions…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Xiaofeng Liu , Fangxu Xing , Jerry L. Prince , Maureen Stone , Georges El Fakhri , Jonghye Woo

Iris-based biometric systems are vulnerable to presentation attacks (PAs), where adversaries present physical artifacts (e.g., printed iris images, textured contact lenses) to defeat the system. This has led to the development of various…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Debasmita Pal , Redwan Sony , Arun Ross

Hearables with integrated microphones may offer communication benefits in noisy working environments, e.g. by transmitting the recorded own voice of the user. Systems aiming at reconstructing the clean and full-bandwidth own voice from…

Audio and Speech Processing · Electrical Eng. & Systems 2024-03-25 Mattes Ohlenbusch , Christian Rollwage , Simon Doclo

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi

Performance of data-driven network for tumor classification varies with stain-style of histopathological images. This article proposes the stain-style transfer (SST) model based on conditional generative adversarial networks (GANs) which is…

Computer Vision and Pattern Recognition · Computer Science 2018-12-21 Hyungjoo Cho , Sungbin Lim , Gunho Choi , Hyunseok Min

In this study, we propose a simple and effective fine-tuning algorithm called "restore-from-restored", which can greatly enhance the performance of fully pre-trained image denoising networks. Many supervised denoising approaches can produce…

Computer Vision and Pattern Recognition · Computer Science 2020-11-19 Seunghwan Lee , Dongkyu Lee , Donghyeon Cho , Jiwon Kim , Tae Hyun Kim

In this paper, we propose a new data augmentation method, Random Shadows and Highlights (RSH) to acquire robustness against lighting perturbations. Our method creates random shadows and highlights on images, thus challenging the neural…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Osama Mazhar , Jens Kober
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