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Objective: This article presents an automatic image processing framework to extract quantitative high-level information describing the micro-environment of glomeruli in consecutive whole slide images (WSIs) processed with different staining…

Computer Vision and Pattern Recognition · Computer Science 2021-05-04 Odyssee Merveille , Thomas Lampert , Jessica Schmitz , Germain Forestier , Friedrich Feuerhake , Cédric Wemmert

Annotating microscopy images for nuclei segmentation is laborious and time-consuming. To leverage the few existing annotations, also across multiple modalities, we propose a novel microscopy-style augmentation technique based on a…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Ye Liu , Sophia J. Wagner , Tingying Peng

Multiple instance learning exhibits a powerful approach for whole slide image-based diagnosis in the absence of pixel- or patch-level annotations. In spite of the huge size of hole slide images, the number of individual slides is often…

Currently, style augmentation is capturing attention due to convolutional neural networks (CNN) being strongly biased toward recognizing textures rather than shapes. Most existing styling methods either perform a low-fidelity style transfer…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Felipe Moreno-Vera , Edgar Medina , Jorge Poco

Immunohistochemistry (IHC) is essential for assessing specific immune biomarkers like Human Epidermal growth-factor Receptor 2 (HER2) in breast cancer. However, the traditional protocols of obtaining IHC stains are resource-intensive,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-10 Aasim Bin Saleem , Amr Ahmed , Ardhendu Behera , Hafeezullah Amin , Iman Yi Liao , Mahmoud Khattab , Pan Jia Wern , Haslina Makmur

Double staining in histopathology, particularly for metaplastic breast cancer, typically employs H&E and P63 dyes. However, P63's tissue damage and high cost necessitate alternative methods. This study introduces xAI-CycleGAN, an advanced…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Tibor Sloboda , Lukáš Hudec , Wanda Benešová

Depth estimation from monocular images is an important task in localization and 3D reconstruction pipelines for bronchoscopic navigation. Various supervised and self-supervised deep learning-based approaches have proven themselves on this…

Image and Video Processing · Electrical Eng. & Systems 2021-09-27 Mert Asim Karaoglu , Nikolas Brasch , Marijn Stollenga , Wolfgang Wein , Nassir Navab , Federico Tombari , Alexander Ladikos

Hematoxylin and eosin (H&E) staining is the clinical standard for assessing tissue morphology, but it lacks molecular-level diagnostic information. In contrast, immunohistochemistry (IHC) provides crucial insights into biomarker expression,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Jingsong Liu , Xiaofeng Deng , Han Li , Azar Kazemi , Christian Grashei , Gesa Wilkens , Xin You , Tanja Groll , Nassir Navab , Carolin Mogler , Peter J. Schüffler

In this work, we propose a novel adversarial defence mechanism for image classification - CARSO - blending the paradigms of adversarial training and adversarial purification in a synergistic robustness-enhancing way. The method builds upon…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Emanuele Ballarin , Alessio Ansuini , Luca Bortolussi

Deep learning has made tremendous advances in computer vision tasks such as image classification. However, recent studies have shown that deep learning models are vulnerable to specifically crafted adversarial inputs that are…

Computer Vision and Pattern Recognition · Computer Science 2019-12-11 Kirthi Shankar Sivamani

The immunohistochemical (IHC) staining of the human epidermal growth factor receptor 2 (HER2) biomarker is widely practiced in breast tissue analysis, preclinical studies and diagnostic decisions, guiding cancer treatment and investigation…

Though CNNs have achieved the state-of-the-art performance on various vision tasks, they are vulnerable to adversarial examples --- crafted by adding human-imperceptible perturbations to clean images. However, most of the existing…

Computer Vision and Pattern Recognition · Computer Science 2019-06-04 Cihang Xie , Zhishuai Zhang , Yuyin Zhou , Song Bai , Jianyu Wang , Zhou Ren , Alan Yuille

Deep neural networks are vulnerable to adversarial examples that mislead models with imperceptible perturbations. In audio, although adversarial examples have achieved incredible attack success rates on white-box settings and black-box…

Sound · Computer Science 2022-10-13 Deng JiaCheng , Dong Li , Yan Diqun , Wang Rangding , Zeng Jiaming

Self-supervised learning has become a popular approach in recent years for its ability to learn meaningful representations without the need for data annotation. This paper proposes a novel image augmentation technique, overlaying images,…

Computer Vision and Pattern Recognition · Computer Science 2023-01-25 Yinheng Li , Han Ding , Shaofei Wang

Self-healing is the ability of a wave packet to spontaneously restore its spatial profile after scattering. As an emergent feature of non-unitary dynamics, it has attracted significant interest in non-Hermitian physics. Here, we…

Quantum Physics · Physics 2026-04-15 Wuping Yang , H. Huang

The goal of this work is to train robust speaker recognition models without speaker labels. Recent works on unsupervised speaker representations are based on contrastive learning in which they encourage within-utterance embeddings to be…

Sound · Computer Science 2020-11-02 Jaesung Huh , Hee Soo Heo , Jingu Kang , Shinji Watanabe , Joon Son Chung

We propose a novel semi-supervised learning approach for classification of histopathology images. We employ strong supervision with patch-level annotations combined with a novel co-training loss to create a semi-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2022-08-30 Bodong Zhang , Beatrice Knudsen , Deepika Sirohi , Alessandro Ferrero , Tolga Tasdizen

Immunohistochemical (IHC) staining provides crucial molecular characterization of tissue samples and plays an indispensable role in the clinical examination and diagnosis of cancers. However, compared with the commonly used Hematoxylin and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Mingzhou Jiang , Jiaying Zhou , Nan Zeng , Mickael Li , Qijie Tang , Chao He , Huazhu Fu , Honghui He

The scarcity of labeled data is a major bottleneck for developing accurate and robust deep learning-based models for histopathology applications. The problem is notably prominent for the task of metastasis detection in lymph nodes, due to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Apostolia Tsirikoglou , Karin Stacke , Gabriel Eilertsen , Jonas Unger

Color inconsistency is an inevitable challenge in computational pathology, which generally happens because of stain intensity variations or sections scanned by different scanners. It harms the pathological image analysis methods, especially…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Bingchao Zhao , Jiatai Lin , Changhong Liang , Zongjian Yi , Xin Chen , Bingbing Li , Weihao Qiu , Danyi Li , Li Liang , Chu Han , Zaiyi Liu
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