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Related papers: Absolutely complex balanced kinetic systems

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Absolute concentration robustness (ACR) is a condition wherein a species in a chemical kinetic system possesses the same value for any positive steady state the network may admit regardless of initial conditions. Thus far, results on ACR…

Dynamical Systems · Mathematics 2020-04-02 Noel T. Fortun , Eduardo R. Mendoza

Robustness against the presence of environmental disruptions can be observed in many systems of chemical reaction network. However, identifying the underlying components of a system that give rise to robustness is often elusive. The…

Dynamical Systems · Mathematics 2020-03-31 Noel T. Fortun , Angelyn R. Lao , Luis F. Razon , Eduardo R. Mendoza

There have been recent theoretic results that provide sufficient conditions for the existence of a species displaying absolute concentration robustness (ACR) in a power law kinetic (PLK) system. One such result involves the detection of ACR…

Chemical Physics · Physics 2020-11-06 Lauro L. Fontanil , Eduardo R. Mendoza , Noel T. Fortun

Studies about the set of positive equilibria ($E_+$) of kinetic systems have been focused on mass action, and not that much on power law kinetic (PLK) systems, even for PL-RDK systems (PLK systems where two reactions with identical reactant…

Dynamical Systems · Mathematics 2022-04-06 Bryan S. Hernandez , Eduardo R. Mendoza

This work introduces a novel approach to study properties of positive equilibria of a chemical reaction network $\mathscr{N}$ endowed with Hill-type kinetics $K$, called a Hill-type kinetic (HTK) system $\left(\mathscr{N},K\right)$,…

Dynamical Systems · Mathematics 2020-09-08 Bryan S. Hernandez , Eduardo R. Mendoza

For a reaction network with species set $\mathscr{S}$, a log-parametrized (LP) set is a non-empty set of the form $E(P, x^*) = \{x \in \mathbb{R}^\mathscr{S}_> \mid \log x - \log x^* \in P^\perp\}$ where $P$ (called the LP set's flux…

Algebraic Geometry · Mathematics 2021-10-27 Angelyn R. Lao , Patrick Vincent N. Lubenia , Daryl M. Magpantay , Eduardo R. Mendoza

A kinetic system has an absolute concentration robustness (ACR) for a molecular species if its concentration remains the same in every positive steady state of the system. Just recently, a condition that sufficiently guarantees the…

Dynamical Systems · Mathematics 2023-04-10 Eduardo R. Mendoza , Dylan Antonio SJ. Talabis , Editha C. Jose , Lauro L. Fontanil

The aim of this article is to build on the use of tools from computational algebra initiated in Craciun, Dickenstein, Shiu, Sturmfels (JSC, 2009), for the study of general kinetic systems, which have a wide range of applications in…

Dynamical Systems · Mathematics 2010-01-07 Alicia Dickenstein , Mercedes Perez Millan

Dynamical systems arising from chemical reaction networks with mass action kinetics are the subject of chemical reaction network theory (CRNT). In particular, this theory provides statements about uniqueness, existence, and stability of…

Dynamical Systems · Mathematics 2014-06-26 Stefan Müller , Georg Regensburger

Motivated by the question of how biological systems maintain homeostasis in changing environments, Shinar and Feinberg introduced in 2010 the concept of absolute concentration robustness (ACR). A biochemical system exhibits ACR in some…

Poly-PL kinetic systems are kinetic systems consisting of nonnegative linear combinations of power law functions. In this contribution, we analyze these kinetic systems using two main approaches: (1) we define a canonical power law…

Dynamical Systems · Mathematics 2021-07-13 Noel T. Fortun , Dylan Antonio SJ. Talabis , Editha C. Jose , Eduardo R. Mendoza

A reaction system exhibits "absolute concentration robustness" (ACR) in some species if the positive steady-state value of that species does not depend on initial conditions. Mathematically, this means that the positive part of the variety…

Dynamical Systems · Mathematics 2022-06-08 Nicolette Meshkat , Anne Shiu , Angélica Torres

Biochemical systems that express certain chemical species of interest at the same level at any positive equilibrium are called "absolute concentration robust" (ACR). These species behave in a stable, predictable way, in the sense that their…

Subcellular Processes · Quantitative Biology 2019-10-15 Daniele Cappelletti , Ankit Gupta , Mustafa Khammash

This paper studies chemical kinetic systems which decompose into weakly reversible complex factorizable (CF) systems. Among power law kinetic systems, CF systems (denoted as PL-RDK systems) are those where branching reactions of a reactant…

Dynamical Systems · Mathematics 2022-03-08 Bryan S. Hernandez , Eduardo R. Mendoza

Reversibility, weak reversibility and deficiency, detailed and complex balancing are generally not "encoded" in the kinetic differential equations but they are realization properties that may imply local or even global asymptotic stability…

Molecular Networks · Quantitative Biology 2011-05-11 Gabor Szederkenyi , Katalin M. Hangos

Poly-PL kinetic systems (PYK) are kinetic systems consisting of nonnegative linear combinations of power law functions. In this contribution, we analyze these kinetic systems using two main approaches: (1) we define a canonical power law…

Dynamical Systems · Mathematics 2021-12-24 Editha C. Jose , Eduardo R. Mendoza , Dylan Antonio SJ. Talabis

A decomposition of a chemical reaction network (CRN) is produced by partitioning its set of reactions. The partition induces networks, called subnetworks, that are "smaller" than the given CRN which, at this point, can be called parent…

Molecular Networks · Quantitative Biology 2021-09-15 Lauro L. Fontanil , Eduardo R. Mendoza

The quantitative convergence to equilibrium for reaction-diffusion systems arising from complex balanced chemical reaction networks with mass action kinetics is studied by using the so-called entropy method. In the first part of the paper,…

Analysis of PDEs · Mathematics 2016-11-11 Laurent Desvillettes , Klemens Fellner , Bao Quoc Tang

We present conditions which guarantee a parametrization of the set of positive equilibria of a generalized mass-action system. Our main results state that (i) if the underlying generalized chemical reaction network has an effective…

Dynamical Systems · Mathematics 2018-05-24 Matthew D. Johnston , Stefan Müller , Casian Pantea

Absolute Concentration Robustness (ACR) was introduced by Shinar and Feinberg as robustness of equilibrium species concentration in a mass action dynamical system. Their aim was to devise a mathematical condition that will ensure robustness…

Dynamical Systems · Mathematics 2022-11-16 Badal Joshi , Gheorghe Craciun
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