English
Related papers

Related papers: Absolutely complex balanced kinetic systems

200 papers

Robustness of biochemical systems has become one of the central questions in Systems Biology, although it is notoriously difficult to formally capture its multifaceted nature. Maintenance of normal system function depends not only on the…

Molecular Networks · Quantitative Biology 2012-03-28 Jost Neigenfind , Sergio Grimbs , Zoran Nikoloski

Recent research in both the experimental and mathematical communities has focused on biochemical interaction systems that satisfy an "absolute concentration robustness" (ACR) property. The ACR property was first discovered experimentally…

Probability · Mathematics 2018-05-22 David F. Anderson , Daniele Cappelletti , Thomas G. Kurtz

Many reaction networks arising in applications are multistationary, that is, they have the capacity for more than one steady state; while some networks exhibit absolute concentration robustness (ACR), which means that some species…

Dynamical Systems · Mathematics 2024-11-20 Nidhi Kaihnsa , Tung Nguyen , Anne Shiu

The detailed balance property is a fundamental property that must be satisfied in all the macroscopic systems with a well defined temperature at each point. On the other hand, many biochemical networks work in non-equilibrium conditions and…

Classical Analysis and ODEs · Mathematics 2025-02-10 E. Franco , J. J. L. Velázquez

The principle of detailed balance states that in equilibrium each elementary process is equilibrated by its reverse process. For many real physico-chemical complex systems (e.g. homogeneous combustion, heterogeneous catalytic oxidation,…

Statistical Mechanics · Physics 2011-08-24 A. N. Gorban , G. S. Yablonsky

Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary differential equations, arising from a reaction network. Such dynamical systems can be generated by many different reaction…

Dynamical Systems · Mathematics 2020-01-01 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

We consider delayed chemical reaction networks with generalized kinetics of product form and show that complex balancing implies that within each positive stoichiometric compatibility class there is a unique positive equilibrium that is…

Dynamical Systems · Mathematics 2024-07-15 Mihály András Vághy , Gábor Szederkényi

Certain chemical reaction networks (CRNs) when modeled as a deterministic dynamical system taken with mass-action kinetics have the property of reaction network detailed balance (RNDB) which is achieved by imposing network-related…

Probability · Mathematics 2014-12-30 Badal Joshi

It is well known that, for mass-action systems, complex-balanced equilibria are asymptotically stable. For generalized mass-action systems, even if there exists a unique complex-balanced equilibrium (in every stoichiometric class and for…

Dynamical Systems · Mathematics 2022-09-14 Balazs Boros , Stefan Müller , Georg Regensburger

One important question that interests those who work in chemical reaction network theory (CRNT) is this: Does the system obtained from a reaction network admit a positive equilibrium and if it does, can there be more than one within a…

Reaction networks have become a major modelling framework in the biological sciences from epidemiology and population biology to genetics and cellular biology. In recent years, much progress has been made on stochastic reaction networks…

Probability · Mathematics 2025-08-14 Linard Hoessly , Carsten Wiuf , Panqiu Xia

Living systems maintain stable internal states despite environmental fluctuations. Absolute concentration robustness (ACR) is a striking homeostatic phenomenon in which the steady-state concentration of a species remains invariant despite…

Dynamical Systems · Mathematics 2025-11-04 Hyukpyo Hong , Diego Rojas La Luz , Gheorghe Craciun

We further clarify the relation between detailed-balanced and complex-balanced equilibria of reversible chemical reaction networks. Our results hold for arbitrary kinetics and also for boundary equilibria. Detailed balance, complex balance,…

Dynamical Systems · Mathematics 2020-09-29 Stefan Müller , Badal Joshi

Quite recently, Cai et al. [arXiv:2006.07165v1] proposed a new concept "absolutely entangled set" for bipartite quantum systems: for any possible choice of global basis, at least one state of the set is entangled. There they presented a…

Quantum Physics · Physics 2020-11-11 Mao-Sheng Li , Man-Hong Yung

In this letter we introduce a class of delayed kinetic systems derived from mass action type reaction network models. We define the time delayed positive stoichiometric compatibility classes and the notion of complex balanced time delayed…

Dynamical Systems · Mathematics 2017-04-21 György Lipták , Katalin M. Hangos , Mihály Pituk , Gábor Szederkényi

This paper presents the derivation of a kinetic-balance condition for explicitly correlated basis functions employed in semi-classical relativistic calculations. Such a condition is important to ensure variational stability in algorithms…

Chemical Physics · Physics 2015-10-26 Benjamin Simmen , Edit Mátyus , Markus Reiher

The principle of detailed balance (DB) states that every kinetic transition in a system with many micro-states, $\mu$, is balanced, on average, with the opposite transition, $\mu_i\leftrightharpoons\mu_j$. Since its introduction by…

Soft Condensed Matter · Physics 2022-12-29 Xulai Sun , Yinqiao Wang , Yujie Wang , Raphael Blumenfeld , Jie Zhang

Generalized mass-action systems are power-law dynamical systems arising from chemical reaction networks. Essentially, every nonnegative ODE model used in chemistry and biology (for example, in ecology and epidemiology) and even in economics…

Dynamical Systems · Mathematics 2023-11-21 Stefan Müller , Georg Regensburger

Absolute concentration robustness (ACR) and concordance are novel concepts in the theory of robustness and stability within Chemical Reaction Network Theory. In this paper, we have extended Shinar and Feinberg's reaction network analysis…

Molecular Networks · Quantitative Biology 2022-09-14 Patrick Vincent N. Lubenia , Eduardo R. Mendoza , Angelyn R. Lao

In a reaction network, the concentration of a species with the property of dynamic absolute concentration robustness (dynamic ACR) converges to the same value independent of the overall initial values. This property endows a biochemical…

Dynamical Systems · Mathematics 2023-09-26 Badal Joshi , Gheorghe Craciun