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We present three data driven model-types for COVID-19 with a minimal number of parameters to provide insights into the spread of the disease that may be used for developing policy responses. The first is exponential growth, widely studied…

Populations and Evolution · Quantitative Biology 2022-05-25 Andrea L. Bertozzi , Elisa Franco , George Mohler , Martin B. Short , Daniel Sledge

The COVID-19 pandemic has had worldwide devastating effects on human lives, highlighting the need for tools to predict its development. Dynamics of such public-health threats can often be efficiently analysed through simple models that help…

Populations and Evolution · Quantitative Biology 2021-06-04 Pedro L. de Andres , Lucia de Andres-Bragado , Linard D. Hoessly

The Susceptible-Exposed-Infectious-Recovered (SEIR) model is applied in several countries to ascertain the spread of the coronavirus disease 2019 (COVID-19). We consider discrete-time SEIR epidemic model in a closed system which does not…

Dynamical Systems · Mathematics 2021-05-04 U. A. Rozikov , S. K. Shoyimardonov

During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…

Physics and Society · Physics 2021-02-24 Marco A. Amaral , Marcelo M. de Oliveira , Marco A. Javarone

Mathematical models describing SARS-CoV-2 dynamics and the corresponding immune responses in patients with COVID-19 can be critical to evaluate possible clinical outcomes of antiviral treatments. In this work, based on the concept of virus…

We introduce a mathematical description of the impact of sociality in the spread of infectious diseases by integrating an epidemiological dynamics with a kinetic modeling of population-based contacts. The kinetic description leads to study…

Physics and Society · Physics 2021-04-02 G. Dimarco , B. Perthame , G. Toscani , M. Zanella

In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

Optimization and Control · Mathematics 2016-12-28 Olga Klimenkova

This paper presents a discrete time probabilistic dynamic for simulating a contact-based epidemic spreading based on discrete time Markov chain process, in particular the attention is addressed to the susceptible-infectious-removed (SIR)…

Physics and Society · Physics 2017-12-22 Fabrizio Angaroni

We study the impact of parameter estimation and state measurement errors on a control framework for optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic…

Systems and Control · Electrical Eng. & Systems 2024-08-08 Baike She , Lei Xin , Shreyas Sundaram , Philip E. Paré

We study a multilayer SIR model with two levels of mixing, namely a global level which is uniformly mixing, and a local level with two layers distinguishing household and workplace contacts, respectively. We establish the large population…

Probability · Mathematics 2023-10-27 Madeleine Kubasch

Several mathematical models in SARS-CoV-2 have shown how target-cell model can help to understand the spread of the virus in the host and how potential candidates of antiviral treatments can help to control the virus. Concepts as…

Optimization and Control · Mathematics 2021-06-24 Mara Perez , Pablo Abuin , Marcelo Actis , Antonio Ferramosca , Esteban A. Hernandez-Vargas , Alejandro H. Gonzalez

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

Populations and Evolution · Quantitative Biology 2021-08-17 Evangelos F. Magirou

The infection dynamics of a population under stationary isolation conditions is modeled. It is underlined that the stationary character of the isolation measures can be expected to imply that an effective SIR model with constant parameters…

Populations and Evolution · Quantitative Biology 2021-10-19 Alejandro Cabo Montes de Oca , Nana Geraldine Cabo Bizet

In this paper, a susceptible-infected-removed (SIR) model has been used to track the evolution of the spread of the COVID-19 virus in four countries of interest. In particular, the epidemic model, that depends on some basic characteristics,…

Populations and Evolution · Quantitative Biology 2020-10-28 Ian Cooper , Argha Mondal , Chris G. Antonopoulos

Most epidemic models assume equal mixing among members of a population. An alternative approach is to model a population as random network in which individuals may have heterogeneous connectivity. This paper builds on previous research by…

Physics and Society · Physics 2007-05-23 Erik Volz

To model the evolution of diseases with extended latency periods and the presence of asymptomatic patients like COVID-19, we define a simple discrete time stochastic SIR-type epidemic model. We include both latent periods as well as the…

Populations and Evolution · Quantitative Biology 2020-05-14 Xavier Bardina , Marco Ferrante , Carles Rovira

Natural fluctuations have played a crucial role in affecting the dynamics of pervasive diseases such as the coronavirus. Examining the effects of irregular unsettling disturbances on epidemic models is important for understanding these…

Dynamical Systems · Mathematics 2024-12-17 Daniel Tesfay , Almaz Tesfay , James Brannan

A probabilistic approach to the epidemic evolution on realistic social-contact networks allows for characteristic differences among subjects, including the individual number and structure of social contacts, and the heterogeneity of the…

Social and Information Networks · Computer Science 2022-02-11 Jan B. Broekaert , Davide La Torre , Faizal Hafiz

This paper seeks to study the evolution of the COVID-19 pandemic based on daily published data from Worldometer website, using a time-dependent SIR model. Our findings indicate that this model fits well such data, for different chosen…

Populations and Evolution · Quantitative Biology 2023-11-28 Rawan H. Madi , Sophie M. Moufawad , Nabil R. Nassif