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We study the well-posedness of an infinite-dimensional Hamilton-Jacobi equation posed on the set of non-negative measures and with a monotonic non-linearity. Our results will be used in a companion work to propose a conjecture and prove…

Analysis of PDEs · Mathematics 2023-08-30 Tomas Dominguez , Jean-Christophe Mourrat

Although many phenotypic traits are determined by a large number of genetic variants, the behavior of allele frequencies in a polygenic trait is not completely understood. The problem is especially challenging when the quantitative trait of…

Populations and Evolution · Quantitative Biology 2026-03-31 Archana Devi , Kavita Jain

Transport across heterogeneous, patchy environments is a ubiquitous phenomenon spanning fields of study including ecological movement, intracellular transport and regions of specialised function in a cell. These regions or patches may be…

Statistical Mechanics · Physics 2017-10-06 Sergei Fedotov , Helena Stage

Starting from a master equation in a quantum Hamilton form we study analytically a nonequilibrium system which is coupled locally to two heat bathes at different temperatures. Based on a lattice gas description an evolution equation for the…

Statistical Mechanics · Physics 2007-05-23 Steffen Trimper , Simone Artz

In the presence of persistent payoff heterogeneity, the evolution of the aggregate strategy hugely depends on the underlying strategy composition under many evolutionary dynamics, while the aggregate dynamic under the standard BRD reduces…

Computer Science and Game Theory · Computer Science 2018-11-01 Dai Zusai

In this paper we study a class of stochastic individual-based models that describe the evolution of haploid populations where each individual is characterised by a phenotype and a genotype. The phenotype of an individual determines its…

Probability · Mathematics 2017-08-07 Martina Baar , Anton Bovier

We derive convenient uniform concentration bounds and finite sample multivariate normal approximation results for quadratic forms, then describe some applications involving variance components estimation in linear random-effects models.…

Statistics Theory · Mathematics 2015-09-16 Lee H. Dicker , Murat A. Erdogdu

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

Probability · Mathematics 2011-01-21 Sylvie Méléard , Sylvie Roelly

In biological systems, expression dynamics that can provide fitted phenotype patterns with respect to a specific function have evolved through mutations. This has been observed in the evolution of proteins for realizing folding dynamics…

Disordered Systems and Neural Networks · Physics 2015-05-13 Ayaka Sakata , Koji Hukushima , Kunihiko Kaneko

In this paper we consider a system of non-linear integro-differential equations (IDEs) describing evolution of a clonally heterogeneous population of malignant white blood cells (leukemic cells) undergoing mutation and clonal selection. We…

Dynamical Systems · Mathematics 2020-04-14 Jan-Erik Busse , Silvia Cuadrado , Anna Marciniak-Czochra

A diffusive Lotka-Volterra competition model is considered for the combined effect of spatial dispersal and spatial variations of resource on the population persistence and exclusion. First it is shown that in a two-species system in which…

Analysis of PDEs · Mathematics 2020-07-21 Wenjie Ni , Junping Shi , Mingxin Wang

This paper is concerned with a model for the dynamics of a single species in a one-dimensional heterogeneous environment. The environment consists of two kinds of patches, which are periodically alternately arranged along the spatial axis.…

Analysis of PDEs · Mathematics 2024-07-04 François Hamel , Frithjof Lutscher , Mingmin Zhang

This study elaborates some examples of a simple evolutionary stochastic rate process where the population rate of change depends on the distribution of properties--so different cohorts change at different rates. We investigate the effect on…

Populations and Evolution · Quantitative Biology 2010-01-26 C. T. J. Dodson

For asexual organisms point mutations correspond to local displacements in the genotypic space, while other genotypic rearrangements represent long-range jumps. We investigate the spreading properties of an initially homogeneous population…

Statistical Mechanics · Physics 2007-05-23 Franco Bagnoli , Michele Bezzi

Spatial extent is a complicating factor in mathematical biology. The possibility that an action at point A cannot immediately affect what happens at point B creates the opportunity for spatial nonuniformity. This nonuniformity must change…

Cellular Automata and Lattice Gases · Physics 2014-01-03 Blake C. Stacey , Andreas Gros , Yaneer Bar-Yam

We considered a {multi-block} molecular model of biological evolution, in which fitness is a function of the mean types of alleles located at different parts (blocks) of the genome. We formulated an infinite population model with selection…

Populations and Evolution · Quantitative Biology 2015-06-12 David B. Saakian , Zara Kirakosyan , Chin-Kun Hu

We consider the spreading dynamics of the Fisher-KPP equation in a shifting environment, by analyzing the limit of the rate function of the solutions. For environments with a weak monotone condition, it was demonstrated in a previous paper…

Analysis of PDEs · Mathematics 2024-10-21 King-Yeung Lam , Gregoire Nadin , Xiao Yu

We consider the cell population dynamics with $n$ different phenotypes. Both the Markovian branching process model (stochastic model) and the ordinary differential equation (ODE) system model (deterministic model) are presented, and…

Populations and Evolution · Quantitative Biology 2022-11-03 Da-Quan Jiang , Yue Wang , Da Zhou

We analyse the behaviour of thin composite plates whose material properties vary periodically in-plane and possess a high degree of contrast between the individual components. Starting from the equations of three-dimensional linear…

Analysis of PDEs · Mathematics 2022-05-03 Marin Bužančić , Kirill Cherednichenko , Igor Velčić , Josip Žubrinić

In this paper, for a variety of nonholonomic (reducible) Hamiltonian systems, we first give to various distributional Hamiltonian systems, by analyzing carefully the dynamics and structures of the nonholonomic Hamiltonian systems. Secondly,…

Symplectic Geometry · Mathematics 2021-06-17 Manuel de León , Hong Wang