Biological Evolution in a Multidimensional Fitness Landscape
Abstract
We considered a {multi-block} molecular model of biological evolution, in which fitness is a function of the mean types of alleles located at different parts (blocks) of the genome. We formulated an infinite population model with selection and mutation, and calculated the mean fitness. For the case of recombination, we formulated a model with a multidimensional fitness landscape (the dimension of the space is equal to the number of blocks) and derived a theorem about the dynamics of initially narrow distribution. We also considered the case of lethal mutations. We also formulated the finite population version of the model in the case of lethal mutations. Our models, derived for the virus evolution, are interesting also for the statistical mechanics and the Hamilton-Jacobi equation as well.
Cite
@article{arxiv.1212.1264,
title = {Biological Evolution in a Multidimensional Fitness Landscape},
author = {David B. Saakian and Zara Kirakosyan and Chin-Kun Hu},
journal= {arXiv preprint arXiv:1212.1264},
year = {2015}
}
Comments
8 pages