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Biological functions are typically performed by groups of cells that express predominantly the same genes, yet display a continuum of phenotypes. While it is known how one genotype can generate such non-genetic diversity, it remains unclear…

Cell Behavior · Quantitative Biology 2017-01-04 Adam James Waite , Nicholas W. Frankel , Yann S. Dufour , Jessica F. Johnston , Junjiajia Long , Thierry Emonet

The subject of this paper is inspired by \cite{CC} and \cite{CCP}. In \cite{CC} the authors investigate the dynamics of a population in a heterogeneous environment by means of diffusive logistic equations. An important part of their study…

Analysis of PDEs · Mathematics 2021-01-20 Claudia Anedda , Fabrizio Cuccu

We study a reaction-diffusion equation with an integral term describing nonlocal consumption of resources. We show that a homogeneous equilibrium can lose its stability resulting in appearance of stationary spatial structures. It is a new…

Analysis of PDEs · Mathematics 2007-05-23 Stephane Genieys , Vitaly Volpert , Pierre Auger

All possible phenotypes are not equally accessible to evolving populations. In fact, only phenotypes of large size, i.e. those resulting from many different genotypes, are found in populations of sequences, presumably because they are…

Populations and Evolution · Quantitative Biology 2023-08-16 Pablo Catalán , Juan Antonio García-Martín , Jacobo Aguirre , José A. Cuesta , Susanna Manrubia

We study quantitative large-time averages for Hamilton--Jacobi equations in a dynamic random environment that is stationary ergodic and has unit-range dependence in time. Our motivation comes from stochastic growth models related to the…

Analysis of PDEs · Mathematics 2026-05-22 Xiaoqin Guo , Wenjia Jing , Hung Vinh Tran , Yuming Paul Zhang

We study the adaptation dynamics of an initially maladapted population evolving via the elementary processes of mutation and selection. The evolution occurs on rugged fitness landscapes which are defined on the multi-dimensional genotypic…

Populations and Evolution · Quantitative Biology 2009-11-13 Kavita Jain

We consider an elliptic partial differential equation with a random diffusion parameter discretized by a stochastic collocation method in the parameter domain and a finite element method in the spatial domain. We prove convergence of an…

Numerical Analysis · Mathematics 2025-06-03 Michael Feischl , Andrea Scaglioni

The mechanisms by which adaptive phenotypes spread within an evolving population after their emergence are understood fairly well. Much less is known about the factors that influence the evolutionary accessibility of such phenotypes, a…

Populations and Evolution · Quantitative Biology 2015-05-13 Wilfred Ndifon , Joshua B. Plotkin , Jonathan Dushoff

Spatial environmental variation can either amplify or suppress the fixation of beneficial mutants in structured populations, yet the interplay of ecological factors and spatial structure in determining which outcome occurs remains…

Populations and Evolution · Quantitative Biology 2026-05-07 Hossein Nemati , Kamran Kaveh , Jakub Svoboda , Mohammad Reza Ejtehadi , Krishnendu Chatterjee

Large sets of genotypes give rise to the same phenotype because phenotypic expression is highly redundant. Accordingly, a population can accept mutations without altering its phenotype, as long as thegenotype mutates into another one on the…

Populations and Evolution · Quantitative Biology 2015-02-18 Susanna Manrubia , José A. Cuesta

An equation describing the evolution of phenotypic distribution is derived using methods developed in statistical physics. The equation is solved by using the singular perturbation method, and assuming that the number of bases in the…

Populations and Evolution · Quantitative Biology 2009-11-13 Katsuhiko Sato , Kunihiko Kaneko

Populations are heterogeneous, deviating in numerous ways. Phenotypic diversity refers to the range of traits or characteristics across a population, where for cells this could be the levels of signalling, movement and growth activity, etc.…

Cell Behavior · Quantitative Biology 2025-04-11 Tommaso Lorenzi , Kevin J Painter , Chiara Villa

Many biological populations exhibit diversity in their strategy for survival and reproduction in a given environment, and microbes are an example. We explore the fate of different strategies under sustained environmental change by…

Populations and Evolution · Quantitative Biology 2025-09-24 Ruixi Huang , David Waxman

The evolutionary dynamics of molecular populations are strongly dependent on the structure of genotype spaces. The map between genotype and phenotype determines how easily genotype spaces can be navigated and the accessibility of…

Populations and Evolution · Quantitative Biology 2019-07-03 Juan Antonio García-Martín , Pablo Catalán , Susanna Manrubia , José A. Cuesta

In this paper, a single population model with memory effect and the heterogeneity of the environment, equipped with the Neumann boundary, is considered. The global existence of a spatial nonhomogeneous steady state is proved by the method…

Dynamical Systems · Mathematics 2020-05-25 Yujia Wang , Chuncheng Wang , Dejun Fan

The main topic of this thesis is the analysis of evolution equations reflecting issues in ecology and population dynamics. In mathematical modelling, the impact of environmental elements and the interaction between species is read into the…

Analysis of PDEs · Mathematics 2021-03-08 Elisa Affili

A general framework of evolutionary dynamics under heterogeneous populations is presented. The framework allows continuously many types of heterogeneous agents, heterogeneity both in payoff functions and in revision protocols and the entire…

Computer Science and Game Theory · Computer Science 2023-10-13 Dai Zusai

We study a one-dimensional spatial population model where the population sizes at each site are chosen according to a translation invariant and ergodic distribution and are uniformly bounded away from 0 and infinity. We suppose that the…

Probability · Mathematics 2019-06-14 Raphaël Forien

We consider here a logistic equation, modeling processes of nonlocal character both in the diffusion and proliferation terms. More precisely, for populations that propagate according to a L\'evy process and can reach resources in a…

Analysis of PDEs · Mathematics 2016-01-22 Luis Caffarelli , Serena Dipierro , Enrico Valdinoci

The nonlocal-to-local asymptotics investigation for evolutionary problems is a central topic both in the theory of PDEs and in functional analysis. More recently, it became the main core of the mathematical analysis of phase-separation…

Analysis of PDEs · Mathematics 2025-11-05 Elisa Davoli , Christian Kuehn , Luca Scarpa , Lara Trussardi