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A proton pencil beam is associated with a surrounding low-dose envelope, originating from nuclear interactions. It is important for treatment planning systems to accurately model this envelope when performing dose calculations for pencil…

Medical Physics · Physics 2015-11-30 David C. Hall , Anastasia Makarova , Harald Paganetti , Bernard Gottschalk

In this manuscript, we investigated the accuracy of the entire chain of phase space files generated by the TrueBeam VirtuaLinac system in clinical treatment plans. Good agreement was obtained between the MC simulation and the clinical…

Medical Physics · Physics 2015-09-24 Yue Yan , Poonam Yadav , Daniel Saenz , Bhudatt R. Paliwal

Head and neck cancer (HNC) patients who undergo radiotherapy (RT) may experience anatomical changes during treatment, compromising the validity of the initial treatment plan, necessitating replanning. However, replanning disrupts clinical…

Robust fine tuning of multi-leaf collimator (MLC) Treatment Planning System (TPS) modeling parameters is crucial for creating an optimal beam model, particularly with the ever-increasing accuracy required for advancing techniques.…

Purpose: ECG and respiratory-gated preclinical cardiac CEST-MRI acquisitions are difficult due to variable saturation recovery with T1, RF interference in the ECG signal, and offset-to-offset variation in Z-magnetization and cardiac phase…

The Gamma Beam System (GBS) is a high brightness LINAC to be installed in Magurele (Bucharest) at the new ELI-NP (Extreme Light Infrastructure - Nuclear Physics) laboratory. The accelerated electrons, with energies ranging from 280 to 720…

Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment…

Medical Physics · Physics 2024-12-02 Sangwook Kim , Aly Khalifa , Thomas G. Purdie , Chris McIntosh

The linear accelerator (LINAC) at the Los Alamos Neu-tron Science Center (LANSCE) consists of Pre-buncher, Main-Buncher, low-energy beam transport (LEBT), four 201.25-MHz Drift Tube Linacs (DTLs) and forty-four 805-MHz Coupled Cavity Linacs…

Accelerator Physics · Physics 2022-11-15 Sungil Kwon , A. Archuleta , L. Castellano , C. Marchwinski , M. Prokop , P. Van Rooy , P. Torrez

We present numerical simulations results on the injection and acceleration of a 10 MeV, 10 pC electrons beam in a plasma wave generated in a gas cell by a 2J, 45 fs laser beam. This modeling is related to the ESCULAP project in which the…

In recent years, ultra-high dose rate (FLASH) radiotherapy has become a novel cancer treatment technique because of its similar tumor-killing efficacy as conventional particle therapy while significantly protecting normal tissues. However,…

Accelerator Physics · Physics 2025-03-04 X. Ding , S. Ruan , H. Ren , G. Wang , R. H. Zhu , J. C. Yang , H. Zhao

A novel phase-space source implementation has been designed for GPU-based Monte Carlo dose calculation engines. Due to the parallelized nature of GPU hardware, it is essential to simultaneously transport particles of the same type and…

Medical Physics · Physics 2013-06-21 Reid Townson , Xun Jia , Zhen Tian , Yan Jiang Graves , Sergei Zavgorodni , Steve B Jiang

The energy recovery linac test facility (ERL-TF), a compact ERL-FEL (free electron laser) two-purpose machine, was proposed at the Institute of High Energy Physics, Beijing. As one important component of the ERL-TF, the photo-injector…

Accelerator Physics · Physics 2015-10-09 Jiao Yi , Xiao Ou-Zheng

We compared the treatment planning performance of RapidArc (RA) vs. CyberKnife (CK) for spinal stereotactic body radiation therapy (SBRT). Ten patients with spinal lesions who had been treated with CK were re-planned with RA, which…

Medical Physics · Physics 2015-03-12 Young Eun Choi , Jungwon Kwak , Si Yeol Song , Eun Kyung Choi , Seung Do Ahn , Byungchul Cho

We developed a three-dimensional radiative transfer code for an ultra-relativistic background flow-field by using the Monte Carlo (MC) method in the context of gamma-ray burst (GRB) emission. For obtaining reliable simulation results in the…

High Energy Astrophysical Phenomena · Physics 2017-09-13 Ayako Ishii , Naofumi Ohnishi , Hiroki Nagakura , Hirotaka Ito , Shoichi Yamada

Recent works in automated radiotherapy treatment planning have used machine learning based on historical treatment plans to infer the spatial dose distribution for a novel patient directly from the planning image. We present an atlas-based…

Medical Physics · Physics 2017-08-02 Chris McIntosh , Mattea Welch , Andrea McNiven , David A. Jaffray , Thomas G. Purdie

We present a detailed study of the six-dimensional phase space of the electron beam produced by the Cornell Energy Recovery Linac Photoinjector, a high-brightness, high repetition rate (1.3 GHz) DC photoemission source designed to drive a…

Purpose: LATTICE, a form of spatially fractionated radiation therapy that delivers high-dose peaks and low-dose valleys within the target, has been clinically utilized for treating bulky tumors. However, its application to…

Medical Physics · Physics 2025-09-08 Nimita Shinde , Weijie Zhang , Yuting Lin , Hao Gao

This paper proposes a monostatic wideband system for integrated sensing and communication (ISAC) at millimeter-wave frequencies, based on multiple-input multiple-output (MIMO) orthogonal frequency-division multiplexing (OFDM). The system…

Signal Processing · Electrical Eng. & Systems 2026-02-23 Tommaso Bacchielli , Lorenzo Pucci , Andrea Giorgetti

Purpose:The recently proposed IPO-IMPT framework allows simultaneous optimization of dose, dose rate, and LET for FLASH treatment planning. Finding solutions to IPO-IMPT is difficult due to computational intensiveness. Nevertheless, an…

Monte Carlo (MC) is generally considered as the most accurate dose calculation tool for particle therapy. However, a proper description of the beam particles kinematics is a necessary input for a realistic simulation. Such a description can…