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Background: Ultra-high-dose-rate (UHDR) radiation therapy has demonstrated promising potential in reducing toxicity to organs-at-risk (OARs). Proton therapy is uniquely positioned to deliver UHDR by leveraging the Bragg peak in conjunction…

Medical Physics · Physics 2025-04-30 Jiayue Han , Ya-Nan Zhu , Aoxiang Wang , Wangyao Li , Yuting Lin , Hao Gao

$\textbf{Purpose}$: To develop a clinical CEST MR fingerprinting (CEST-MRF) method for brain tumor quantification using EPI acquisition and deep learning reconstruction. $\textbf{Methods}$: A CEST-MRF pulse sequence originally designed for…

Accurate proton dose calculation using Monte Carlo (MC) is computationally demanding in workflows like robust optimisation, adaptive replanning, and probabilistic inference, which require repeated evaluations. To address this, we develop a…

Machine Learning · Statistics 2025-09-24 Aaron Pim , Tristan Pryer

A special beam line for high energy electron radiography is designed, including achromat and imaging systems. The requirement of the angle and position correction on the target from imaging system can be approximately realized by fine…

The AVATAR system utilizes a radiolucent video display to help relax and immobilize pediatric patients during radiotherapy. This study investigates the use of OLED (Organic Light Emitting Diode) displays, which offer superior image quality…

Energy recovery linac (ERL) holds great promise for generating high repetition-rate and high brightness electron beams. The application of ERL to drive a free-electron laser is currently limited by its low peak current. In this paper, we…

Accelerator Physics · Physics 2021-08-16 Zhentang Zhao , Zhen Wang , Chao Feng , Si Chen , Lu Cao

In this study, the absorbed dose calculation for the cerebral region is refined using the Geant4 software, along with the ROOT and GATE programs. This approach provides a detailed statistical analysis of positron trajectories within a water…

Medical Physics · Physics 2025-05-06 Walter Sabalza-Castillejo , Miguel Martin-Landrove

Diffusing alpha-emitters radiation therapy (Alpha-DaRT) is a new modality that uses alpha particles to treat solid tumors. Alpha-DaRT employs interstitial sources loaded with low activities of Radium-224, which release a chain of…

Dielectric metasurfaces provide a unique platform for efficient harmonic generation and optical wavefront manipulation at the nanoscale. Tailoring phase and amplitude of a nonlinearly generated wave with a high emission efficiency using…

Optics · Physics 2022-10-03 David Hähnel , Jens Förstner , Viktor Myroshnychenko

PURPOSE: Permanent breast seed implant (PBSI) using 103Pd is emerging as an effective adjuvant radiation technique for early-stage breast cancer. However, clinical dose evaluations follow the water-based TG-43 approach with its considerable…

Medical Physics · Physics 2021-05-27 Stephen G. Deering , Michelle Hilts , Deidre Batchelar , Juanita Crook , Rowan M. Thomson

Purpose: A novel rotating gamma stereotactic radiosurgery (SRS) system (Galaxy RTi) with real-time image guidance technology has been developed for high-precision SRS and frameless fractionated stereotactic radiotherapy (SRT). This work…

Medical Physics · Physics 2022-10-11 Huan Liu , Ahmed Eldib , Lili Chen , Bin Wang , Shidong Li , Curtis Miyamoto , CM Charlie Ma

CLIC is a linear $e^+e^-$ ($\gamma\gamma$) collider project which uses a drive beam to accelerate the main beam. The drive beam provides RF power for each corresponding unit of the main linac through energy extracting RF structures. CLIC…

Accelerator Physics · Physics 2007-05-23 Husnu Aksakal

Purpose: The purpose of the present article is to propose a modified version of the D-shaped collimator used at the Univ. Hosp. of Essen for retinoblastoma treatment that reduces even further the irradiation field with the scope to reduce…

Medical Physics · Physics 2018-09-26 P. A. Mayorga , L. Brualla , W. Sauerwein , A. M. Lallena

Recent advances in propagation-based phase-contrast imaging, such as hierarchical imaging, have enabled the visualization of internal structures in large biological specimens and material samples. However, modulation-based techniques, which…

Volumetric Modulated Arc Therapy (VMAT) revolutionizes cancer treatment by precisely delivering radiation while sparing healthy tissues. Fluence maps generation, crucial in VMAT planning, traditionally involves complex and iterative, and…

Image and Video Processing · Electrical Eng. & Systems 2025-02-06 Simon Arberet , Florin C. Ghesu , Riqiang Gao , Martin Kraus , Jonathan Sackett , Esa Kuusela , Ali Kamen

Achieving maximum electron beam brightness in photoinjectors requires detailed control of the 3D bunch shape and precise tuning of the beam focusing. Even in state-of-the-art designs, slice emittance growth due to nonlinear space charge…

Accelerator Physics · Physics 2024-04-10 W. H. Li , A. C. Bartnik , A. Fukasawa , M. Kaemingk , G. Lawler , N. Majernik , J. B. Rosenzweig , J. M. Maxson

Purpose: To investigate whether an AI-based method can detect subtle inter-fraction changes in MR-Linac images acquired during radiotherapy and explore the broader potential of MRLinac imaging. Methods: This retrospective study included…

Image and Video Processing · Electrical Eng. & Systems 2026-04-22 Seungbin Park , Peilin Wang , Ryan Pennell , Emily S. Weg , Himanshu Nagar , Timothy McClure , Mert R. Sabuncu , Daniel Margolis , Heejong Kim

In this work, we propose a Machine Learning model that generates an adjustable 3D dose distribution for external beam radiation therapy for head-and-neck cancer treatments. In contrast to existing Machine Learning methods that provide a…

Multi-task learning (MTL) is a powerful approach in deep learning that leverages the information from multiple tasks during training to improve model performance. In medical imaging, MTL has shown great potential to solve various tasks.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Sangwook Kim , Thomas G. Purdie , Chris McIntosh

Injected beam energy and energy spread are critical parameters affecting the performance of our rapid cycling synchrotron (RCS). A real-time energy monitoring system is being installed to examine the H- beam out of the Intense Pulsed…

Accelerator Physics · Physics 2009-09-25 J. C. Dooling , F. R. Brumwell , M. K. Lien , G. E. McMichael
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