Related papers: Towards Understanding the COVID-19 Case Fatality R…

Forecasting new cases, hospitalizations, and disease-induced deaths is an important part of infectious disease surveillance and helps guide health officials in implementing effective countermeasures. For disease surveillance in the U.S.,…

The accounts of medical trials provide very detailed information about the patients' health conditions. In contrast, only minimal data are usually given about demographic factors. Yet, some of these factors can have a notable impact on the…

This paper deals with the problem of estimating variables in nonlinear models for the spread of disease and its application to the COVID-19 epidemic. First unconstrained methods are revisited and they are shown to correspond to the…

The objective of this study was to investigate the importance of multiple county-level features in the trajectory of COVID-19. We examined feature importance across 2,787 counties in the United States using a data-driven machine learning…

The crisis caused by COVID-19 revealed the global unpreparedness to handle the impact of a pandemic. In this paper, we present a statistical analysis of the data related to the COVID-19 outbreak in China, specifically the infection speed,…

Timely estimation of the current value for COVID-19 reproduction factor $R$ has become a key aim of efforts to inform management strategies. $R$ is an important metric used by policy-makers in setting mitigation levels and is also important…

This study explored how population mobility flows form commuting networks across US counties and influence the spread of COVID-19. We utilized 3-level mixed effects negative binomial regression models to estimate the impact of network…

We present a modified age-structured SIR model based on known patterns of social contact and distancing measures within Washington, USA. We find that population age-distribution has a significant effect on disease spread and mortality rate,…

The first known case of Coronavirus disease 2019 (COVID-19) was identified in December 2019. It has spread worldwide, leading to an ongoing pandemic, imposed restrictions and costs to many countries. Predicting the number of new cases and…

COVID-19 outbreak has rapidly evolved into a global pandemic. The impact of COVID-19 on patient journeys in oncology represents a new risk to interpretation of trial results and its broad applicability for future clinical practice. We…

Background: The corona virus disease 2019 (COVID-19) pandemic, which is caused by severe acute respiratory syndrome coronavirus 2, is still localized outbreak and has resulted in a high rate of infection and severe disease in older patients…

The COVID-19 vaccine development, manufacturing, transportation, and administration proved an extreme logistics operation of global magnitude. Global vaccination levels, however, remain a key concern in preventing the emergence of new…

Facing the world wide coronavirus disease 2019 (COVID-19) pandemic, a new fitting method (QDF, quasi-distribution fitting) which could be used to analyze the data of COVID-19 is developed based on piecewise quasi-uniform B-spline curves.…

A number of models in mathematical epidemiology have been developed to account for control measures such as vaccination or quarantine. However, COVID-19 has brought unprecedented social distancing measures, with a challenge on how to…

Introduction: Endpoint choice for randomized controlled trials of treatments for COVID-19 is complex. A new disease brings many uncertainties, but trials must start rapidly. COVID-19 is heterogeneous, ranging from mild disease that improves…

The rapid development of vaccines to combat the spread of COVID-19 disease caused by the SARS-CoV-2 virus is a great scientific achievement. Before the development of the COVID-19 vaccines, most studies capitalized on the available data…

The rapid spread of the novel coronavirus (COVID-19) has severely impacted almost all countries around the world. It not only has caused a tremendous burden on health-care providers to bear, but it has also brought severe impacts on the…

Background: The negative effects of the COVID-19 pandemic on the mental health and well-being of populations are an important public health issue. Our study aims to determine the underlying factors shaping mental health trajectories during…

Socio-economic disparities quite often have a central role in the unfolding of large-scale catastrophic events. One of the most concerning aspects of the ongoing COVID-19 pandemics is that it disproportionately affects people from Black and…

During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of…