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During 2020, the infection rate of COVID-19 has been investigated by many scholars from different research fields. In this context, reliable and interpretable forecasts of disease incidents are a vital tool for policymakers to manage…

Machine Learning · Computer Science 2021-01-05 Cornelius Fritz , Emilio Dorigatti , David Rügamer

Early detection of COVID-19 is an ongoing area of research that can help with triage, monitoring and general health assessment of potential patients and may reduce operational strain on hospitals that cope with the coronavirus pandemic.…

Machine Learning · Computer Science 2022-01-11 Omid Rohanian , Samaneh Kouchaki , Andrew Soltan , Jenny Yang , Morteza Rohanian , Yang Yang , David Clifton

The COVID-19 pandemic and the mitigation policies implemented in response to it have resulted in economic losses worldwide. Attempts to understand the relationship between economics and epidemiology has lead to a new generation of…

During decades, mathematical models have been used to predict the behavior of physical and biologic systems, and to define strategies aiming the minimization of the effects regarding different types of diseases. In the present days, the…

Populations and Evolution · Quantitative Biology 2020-04-22 Gustavo Barbosa Libotte , Fran Sérgio Lobato , Gustavo Mendes Platt , Antônio José da Silva Neto

We propose the use of a conjecturing machine that suggests feature relationships in the form of bounds involving nonlinear terms for numerical features and boolean expressions for categorical features. The proposed Conjecturing framework…

Machine Learning · Computer Science 2023-07-18 J. P. Brooks , D. J. Edwards , C. E. Larson , N. Van Cleemput

A configuration model for epidemic spread, based on a scale-free network, is introduced. We obtain the analytical solutions describing both unstable and stable dynamics of the epidemic spreading, and demonstrate how these regimes can…

Physics and Society · Physics 2020-07-15 Alexander I Nesterov , Pablo Héctor Mata Villafuerte , Gennady P Berman

Mathematical models describing SARS-CoV-2 dynamics and the corresponding immune responses in patients with COVID-19 can be critical to evaluate possible clinical outcomes of antiviral treatments. In this work, based on the concept of virus…

For the description of a pandemic mathematical models could be interesting. Both for physicians and politicians as a base for decisions to treat the disease. The responsible estimation of parameters is a main issue of mathematical pandemic…

Populations and Evolution · Quantitative Biology 2020-04-15 Günter Bärwolff

COVID-19, a novel coronavirus, is currently a major worldwide threat. It has infected more than a million people globally leading to hundred-thousands of deaths. In such grave circumstances, it is very important to predict the future…

Populations and Evolution · Quantitative Biology 2022-09-16 Hiteshi Tandon , Prabhat Ranjan , Tanmoy Chakraborty , Vandana Suhag

Matching is one of the most widely used causal inference frameworks in observational studies. However, all the existing matching-based causal inference methods are designed for either a single treatment with general treatment types (e.g.,…

Medicine is moving from a curative discipline to a preventative discipline relying on personalised and precise treatment plans. The complex and multi level pathophysiological patterns of most diseases require a systemic medicine approach…

Computational Engineering, Finance, and Science · Computer Science 2020-07-21 Pietro Barbiero , Pietro Lió

In the wake of COVID-19, every government huddles to find the best interventions that will reduce the number of infection cases while minimizing the economic impact. However, with many intervention policies available, how should one decide…

Optimization and Control · Mathematics 2021-04-19 Chang Liu , Akshay Budhkar

Artificial intelligence (AI) and machine learning (ML) have made a paradigm shift in health care which, eventually can be used for decision support and forecasting by exploring the medical data. Recent studies showed that AI and ML can be…

Understanding the spatio-temporal patterns of the coronavirus disease 2019 (COVID-19) is essential to construct public health interventions. Spatially referenced data can provide richer opportunities to understand the mechanism of the…

Methodology · Statistics 2022-07-15 Jaewoo Park , Seorim Yi , Won Chang , Jorge Mateu

We continue our study of a model for cancer treatment, constructed in Dutta et. al., 2025, by adding Virotherapy to the Chemotherapy and Immunotherapy studied there. It is a dynamical system model for the spread of cancer in healthy tissue.…

Other Quantitative Biology · Quantitative Biology 2026-03-02 Tarini Kumar Dutta , Silmera A Sangma , Janice Moore , Meir Shillor

Drug development is time-consuming and expensive. Repurposing existing drugs for new therapies is an attractive solution that accelerates drug development at reduced experimental costs, specifically for Coronavirus Disease 2019 (COVID-19),…

Biomolecules · Quantitative Biology 2022-02-11 Xiaoqin Pan , Xuan Lin , Dongsheng Cao , Xiangxiang Zeng , Philip S. Yu , Lifang He , Ruth Nussinov , Feixiong Cheng

The outbreaks of Coronavirus Disease 2019 (COVID-19) have impacted the world significantly. Modeling the trend of infection and real-time forecasting of cases can help decision making and control of the disease spread. However, data-driven…

Populations and Evolution · Quantitative Biology 2020-09-18 Zhijian Li , Yunling Zheng , Jack Xin , Guofa Zhou

To better understand the potential of drug repurposing in COVID-19, we analyzed control strategies over essential host factors for SARS-CoV-2 infection. We constructed comprehensive directed protein-protein interaction networks integrating…

We study mixed-integer programming formulations for the piecewise linear lower and upper bounds (in other words, piecewise linear relaxations) of nonlinear functions that can be modeled by a new class of combinatorial disjunctive…

Optimization and Control · Mathematics 2023-05-01 Bochuan Lyu , Illya V. Hicks , Joey Huchette

Millions of people are infected by the coronavirus disease 2019 (COVID19) around the world. Machine Learning (ML) techniques are being used for COVID19 detection research from the beginning of the epidemic. This article represents the…

Machine Learning · Computer Science 2020-08-18 Md Fahimuzzman Sohan