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This paper is concerned with the design of intermittent non-pharmaceutical strategies to mitigate the spread of the COVID-19 epidemic exploiting network epidemiological models. Specifically, by studying a variational equation for the…

Populations and Evolution · Quantitative Biology 2022-04-14 Marco Coraggio , Shihao Xie , Francesco De Lellis , Giovanni Russo , Mario di Bernardo

Heterogeneous treatment effect estimation is critical in oncology, particularly in multi-arm trials with overlapping therapeutic components and long-term survivors. These shared mechanisms pose a central challenge to identifying causal…

Methodology · Statistics 2025-10-29 Peter Chang , John Kairalla , Arkaprava Roy

Drug combinations play an important role in therapeutics due to its better efficacy and reduced toxicity. Recent approaches have applied machine learning to identify synergistic combinations for cancer, but they are not applicable to new…

Biomolecules · Quantitative Biology 2020-12-01 Wengong Jin , Regina Barzilay , Tommi Jaakkola

The new Coronavirus is spreading rapidly, and it has taken the lives of many people so far. The virus has destructive effects on the human lung, and early detection is very important. Deep Convolution neural networks are such powerful tools…

Image and Video Processing · Electrical Eng. & Systems 2021-10-06 Mohammad Saber Iraji , Mohammad-Reza Feizi-Derakhshi , Jafar Tanha

The spread of COVID-19 has been thwarted in most countries through non-pharmaceutical interventions. In particular, the most effective measures in this direction have been the stay-at-home and closure strategies of businesses and schools.…

Physics and Society · Physics 2022-05-04 G. Dimarco , G. Toscani , M. Zanella

We demonstrate an approach to replicate and forecast the spread of the SARS-CoV-2 (COVID-19) pandemic using the toolkit of probabilistic programming languages (PPLs). Our goal is to study the impact of various modeling assumptions and…

Machine Learning · Statistics 2022-03-08 Swapneel Mehta , Noah Kasmanoff

In December 2019, a novel virus called COVID-19 had caused an enormous number of causalities to date. The battle with the novel Coronavirus is baffling and horrifying after the Spanish Flu 2019. While the front-line doctors and medical…

Machine Learning · Computer Science 2023-03-30 MD Abdullah Al Nasim , Aditi Dhali , Faria Afrin , Noshin Tasnim Zaman , Nazmul Karimm , Md Mahim Anjum Haque

By the end of July 2020, the COVID-19 pandemic had infected more than seventeen million people and had spread to almost all countries worldwide. In response, many countries all over the world have used different methods to reduce the…

Physics and Society · Physics 2020-08-21 Hilla De-Leon , Francesco Pederiva

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

Several mixed-effects models for longitudinal data have been proposed to accommodate the non-linearity of late-life cognitive trajectories and assess the putative influence of covariates on it. No prior research provides a side-by-side…

Applications · Statistics 2024-03-07 Maude Wagner , Donald R. Hedeker , Tianhao Wang , Graciela Muniz-Terrera , Ana W. Capuano

The novelty of new human coronavirus COVID-19/SARS-CoV-2 and the lack of effective drugs and vaccines gave rise to a wide variety of strategies employed to fight this worldwide pandemic. Many of these strategies rely on the repositioning of…

Molecular Networks · Quantitative Biology 2021-06-09 Giulia Fiscon , Federica Conte , Lorenzo Farina , Paola Paci

We propose a new method that uses tensor completion to estimate causal effects with multivariate longitudinal data, data in which multiple outcomes are observed for each unit and time period. Our motivation is to estimate the number of…

Methodology · Statistics 2023-11-21 Jonathan Auerbach , Martin Slawski , Shixue Zhang

The COVID-19 Open Research Dataset (CORD-19) is a growing resource of scientific papers on COVID-19 and related historical coronavirus research. CORD-19 is designed to facilitate the development of text mining and information retrieval…

Coronavirus disease (COVID-19) which is caused by SARS-COV2 has become a pandemic. This disease is highly infectious and potentially fatal, causing a global public health concern. To contain the spread of COVID-19, governments are adopting…

Physics and Society · Physics 2020-06-22 Sayantari Ghosh , Saumik Bhattacharya

We discuss an approach for fitting robust nonlinear regression models, which can be employed to model and predict the contagion dynamics of the Covid-19 in Italy. The focus is on the analysis of epidemic data using robust dose-response…

To strengthen inferences meta analyses are commonly used to summarize information from a set of independent studies. In some cases, though, the data may not satisfy the assumptions underlying the meta analysis. Using three Bayesian methods…

Applications · Statistics 2022-04-07 Dexter Cahoy , Joseph Sedransk

The Coronavirus, known as COVID-19, which appeared in 2019 in China, has significantly affected global health and become a huge burden on health institutions all over the world. These effects are continuing today. One strategy for limiting…

Neural and Evolutionary Computing · Computer Science 2023-02-07 Maryam T. Abdulkhaleq , Tarik A. Rashid , Bryar A. Hassan , Abeer Alsadoon , Nebojsa Bacanin , Amit Chhabra , S. Vimal

In this study, we formulate a mathematical model incorporating age specific transmission dynamics of COVID-19 to evaluate the role of vaccination and treatment strategies in reducing the size of COVID-19 burden. Initially, we establish the…

Populations and Evolution · Quantitative Biology 2021-02-22 Bishal Chhetri , D. k. k. Vamsi , S Balasubramanian , Carani B Sanjeevi

A dataset of COVID-19-related scientific literature is compiled, combining the articles from several online libraries and selecting those with open access and full text available. Then, hierarchical nonnegative matrix factorization is used…

Very recently the new pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified and the coronavirus disease 2019 (COVID-19) declared a pandemic by the World Health Organization. The pandemic has a number of…

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