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Related papers: Modeling epigenetic evolutionary algorithms: An ap…

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Genetic algorithms are a well-known example of bio-inspired heuristic methods. They mimic natural selection by modeling several operators such as mutation, crossover, and selection. Recent discoveries about Epigenetics regulation processes…

Neural and Evolutionary Computing · Computer Science 2023-03-20 Mohamed Djallel Dilmi , Hanene Azzag , Mustapha Lebbah

Epigenetics encompasses mechanisms that can alter the expression of genes without changing the underlying genetic sequence. The epigenetic regulation of gene expression is initiated and sustained by several mechanisms such as DNA…

Genomics · Quantitative Biology 2025-04-08 Muhammad Tahir , Mahboobeh Norouzi , Shehroz S. Khan , James R. Davie , Soichiro Yamanaka , Ahmed Ashraf

Hundreds of Evolutionary Computation approaches have been reported. From an evolutionary perspective they focus on two fundamental mechanisms: cultural inheritance in Swarm Intelligence and genetic inheritance in Evolutionary Algorithms.…

Neural and Evolutionary Computing · Computer Science 2022-11-28 Sizhe Yuen , Thomas H. G. Ezard , Adam J. Sobey

The significant role of epigenetic mechanisms within natural systems has become increasingly clear. This paper uses a recently presented abstract, tunable Boolean genetic regulatory network model to explore aspects of epigenetics. It is…

Neural and Evolutionary Computing · Computer Science 2013-06-21 Larry Bull

This paper describes an Artificial Embryology method (called ``Epigenetic Tracking'') to generate predefined arbitrarily shaped 2-dimensional arrays of cells by means of evolutionary techniques. It is based on a model of development, whose…

Adaptation and Self-Organizing Systems · Physics 2008-05-19 Alessandro Fontana

Evolutionary Computation is a group of biologically inspired algorithms used to solve complex optimisation problems. It can be split into Evolutionary Algorithms, which take inspiration from genetic inheritance, and Swarm Intelligence…

Neural and Evolutionary Computing · Computer Science 2021-08-11 Sizhe Yuen , Thomas H. G. Ezard , Adam J. Sobey

Genetic Regulatory Networks (GRNs) plays a vital role in the understanding of complex biological processes. Modeling GRNs is significantly important in order to reveal fundamental cellular processes, examine gene functions and understanding…

Computational Engineering, Finance, and Science · Computer Science 2012-05-10 Khalid Raza , Rafat Parveen

Epigenetic Tracking is a mathematical model of biological cells, originally conceived to study embryonic development. Computer simulations proved the capacity of the model to generate complex 3-dimensional cellular structures, and the…

Cell Behavior · Quantitative Biology 2015-07-07 Alessandro Fontana

We introduce and experimentally demonstrate the utility of tag-based genetic regulation, a new genetic programming (GP) technique that allows programs to dynamically adjust which code modules to express. Tags are evolvable labels that…

Neural and Evolutionary Computing · Computer Science 2021-07-13 Alexander Lalejini , Matthew Andres Moreno , Charles Ofria

Despite the success of metaheuristic algorithms in solving complex network optimization problems, they often struggle with adaptation, especially in dynamic or high-dimensional search spaces. Traditional approaches can become stuck in local…

Neural and Evolutionary Computing · Computer Science 2025-01-13 Boris Kriuk , Keti Sulamanidze , Fedor Kriuk

"Epigenetic Tracking" is a model of systems of biological cells, able to generate arbitrary 2 or 3-dimensional cellular shapes of any kind and complexity (in terms of number of cells, number of colours, etc.) starting from a single cell. If…

Adaptation and Self-Organizing Systems · Physics 2011-11-18 Alessandro Fontana

Adaptation mechanism of cells on the basis of stochastic gene expression and epigenetic modification is proposed. From marginally stable states generated by epigenetic modification, a gene expression pattern that achieves greater cell…

Molecular Networks · Quantitative Biology 2019-01-18 Yusuke Himeoka , Kunihiko Kaneko

This paper deals with a model of cellular growth called "Epigenetic Tracking", whose key features are: i) distinction bewteen "normal" and "driver" cells; ii) presence in driver cells of an epigenetic memory, that holds the position of the…

Cell Behavior · Quantitative Biology 2009-05-01 Alessandro Fontana

This study presents the approach to analyzing the evolution of an arbitrary complex system whose behavior is characterized by a set of different time-dependent factors. The key requirement for these factors is only that they must contain an…

Data Analysis, Statistics and Probability · Physics 2020-12-01 Anatolii V. Mokshin , Vladimir V. Mokshin , Diana A. Mirziyarova

Evolutionary success depends on the capacity to adapt: organisms must respond to environmental challenges through both genetic innovation and lifetime learning. The gene-centric paradigm attributes evolutionary causality exclusively to…

Neural and Evolutionary Computing · Computer Science 2026-02-03 Nam H. Le

The hierarchical organisation of cell identity is a fundamental feature of animal development with rich and well-characterized experimental phenomenology, yet the mechanisms driving its emergence remain unknown. The regulation of cell…

Cell Behavior · Quantitative Biology 2025-04-08 Anton Grishechkin , Abhirup Mukherjee , Omer Karin

Plasticity-led evolution is a form of evolution where a change in the environment induces novel traits via phenotypic plasticity, after which the novel traits are genetically accommodated over generations under the novel environment. This…

Populations and Evolution · Quantitative Biology 2023-01-18 Eden Tian Hwa Ng , Akira R. Kinjo

Biological phenotypes are products of complex evolutionary processes in which selective forces influence multiple biological trait measurements in unknown ways. Phylogenetic factor analysis disentangles these relationships across the…

Genetic programming and artificial life systems commonly employ tag-matching schemes to determine interactions between model components. However, the implications of criteria used to determine affinity between tags with respect to…

Neural and Evolutionary Computing · Computer Science 2023-10-10 Matthew Andres Moreno , Alexander Lalejini , Charles Ofria

Evolution Strategies are inspired in biology and part of a larger research field known as Evolutionary Algorithms. Those strategies perform a random search in the space of admissible functions, aiming to optimize some given objective…

Optimization and Control · Mathematics 2007-12-30 Pedro A. F. Cruz , Delfim F. M. Torres
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