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We consider evolution of a large population, where fitness of each organism is defined by many phenotypical traits. These traits result from expression of many genes. We propose a new model of gene regulation, where gene expression is…

Populations and Evolution · Quantitative Biology 2016-09-29 John Reinitz , Sergey Vakulenko , Dmitri Grigoriev , Andreas Weber

We study the evolution of artificial learning systems by means of selection. Genetic programming is used to generate a sequence of populations of algorithms which can be used by neural networks for supervised learning of a rule that…

Biological Physics · Physics 2009-11-07 Juan Pablo Neirotti , Nestor Caticha

This paper describes a methodology for analyzing the evolutionary dynamics of genetic programming (GP) using genealogical information, diversity measures and information about the fitness variation from parent to offspring. We introduce a…

Machine Learning · Computer Science 2021-08-25 Bogdan Burlacu , Michael Affenzeller , Michael Kommenda

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

The process of morphogenesis is an evolution of the shape of an organism together with the differentiation of its parts. This process encompasses numerous biological processes ranging from embryogenesis to regeneration following crisis such…

Other Quantitative Biology · Quantitative Biology 2019-09-23 N. Bessonov , O. Butuzova , A. Minarsky , R. Penner , C. Soule , A. Tosenberger , N. Morozova

A review of the mechanisms of speciation is performed. The mechanisms of the evolution of species, taking into account the feedback of the state of the environment and mechanisms of the emergence of complexity, are considered. It is shown…

Populations and Evolution · Quantitative Biology 2018-07-18 Alexey V. Melkikh , Alexey V. Melkikh , Andrei Khrennikov

How do mammalian cells that share the same genome exist in notably distinct phenotypes, exhibiting differences in morphology, gene expression patterns, and epigenetic chromatin statuses? Furthermore how do cells of different phenotypes…

Molecular Networks · Quantitative Biology 2015-04-27 Jianhua Xing , Jin Yu , Hang Zhang , Xiao-Jun Tian

Cells often exhibit different and stable phenotypes from the same DNA sequence. Robustness and plasticity of such cellular states are controlled by diverse transcriptional and epigenetic mechanisms, among them the modification of…

Molecular Networks · Quantitative Biology 2015-06-18 Daniel Jost

Phylogenetic analyses of gene expression have great potential for addressing a wide range of questions. These analyses will, for example, identify genes that have evolutionary shifts in expression that are correlated with evolutionary…

Populations and Evolution · Quantitative Biology 2014-01-14 Casey W. Dunn , Xi Luo , Zhijin Wu

We propose a physical model for developmental process at cellular level to discuss the mechanism of epigenetic landscape. In our simplified model, a minimal model, the network of the interaction among cells generates the landscape…

Cell Behavior · Quantitative Biology 2014-02-04 Motoki Nakagawa , Osamu Narikiyo

Data-efficient image classification is a challenging task that aims to solve image classification using small training data. Neural network-based deep learning methods are effective for image classification, but they typically require…

Neural and Evolutionary Computing · Computer Science 2022-12-05 Ying Bi , Bing Xue , Mengjie Zhang

Evolutionary dynamics are shaped by a variety of fundamental, generic drivers, including spatial structure, ecology, and selection pressure. These drivers impact the trajectory of evolution, and have been hypothesized to influence…

Populations and Evolution · Quantitative Biology 2025-06-04 Matthew Andres Moreno , Santiago Rodriguez-Papa , Emily Dolson

Gene expression-based heterogeneity analysis has been extensively conducted. In recent studies, it has been shown that network-based analysis, which takes a system perspective and accommodates the interconnections among genes, can be more…

Methodology · Statistics 2023-08-09 Rong Li , Qingzhao Zhang , Shuangge Ma

Gene regulation is an important fundamental biological process. The regulation of gene expression is managed through a variety of methods including epigenetic processes (e.g., DNA methylation). Understanding the role of epigenetic changes…

Molecular Networks · Quantitative Biology 2021-06-01 James Brunner , Jacob Kim , Timothy Downing , Eric Mjolsness , Kord M. Kober

Recent advances in data-driven evolutionary algorithms (EAs) have demonstrated the potential of leveraging historical data to improve optimization accuracy and adaptability. Despite these advancements, existing methods remain reliant on…

Neural and Evolutionary Computing · Computer Science 2026-02-16 Tao Jiang , Kebin Sun , Zhenyu Liang , Ran Cheng , Yaochu Jin , Kay Chen Tan

Natural selection is general and powerful concept not only to explain evolutionary processes of biological organisms but also to design engineering systems such as genetic algorithms and particle filters. There is a surge of interest, both…

Populations and Evolution · Quantitative Biology 2021-06-09 So Nakashima , Tetsuya J. Kobayashi

Ensemble learning has gained success in machine learning with major advantages over other learning methods. Bagging is a prominent ensemble learning method that creates subgroups of data, known as bags, that are trained by individual…

Neural and Evolutionary Computing · Computer Science 2022-09-07 Giang Ngo , Rodney Beard , Rohitash Chandra

In our previous work, we introduced the rule-based Bayesian Regression, a methodology that leverages two concepts: (i) Bayesian inference, for the general framework and uncertainty quantification and (ii) rule-based systems for the…

Machine Learning · Statistics 2022-03-01 Themistoklis Botsas , Lachlan R. Mason , Omar K. Matar , Indranil Pan

Genetic algorithms are modeled after the biological evolutionary processes that use natural selection to select the best species to survive. They are heuristics based and low cost to compute. Genetic algorithms use selection, crossover, and…

Neural and Evolutionary Computing · Computer Science 2020-05-28 Mee Seong Im , Venkat R. Dasari

The two most fundamental processes describing change in biology, development and evolu-tion, occur over drastically different timescales, difficult to reconcile within a unified framework. Development involves temporal sequences of cell…

Biological Physics · Physics 2020-09-08 Enrico Borriello , Sara I. Walker , Manfred D. Laubichler