The significant role of epigenetic mechanisms within natural systems has become increasingly clear. This paper uses a recently presented abstract, tunable Boolean genetic regulatory network model to explore aspects of epigenetics. It is shown how dynamically controlling transcription via a DNA methylation-inspired mechanism can be selected for by simulated evolution under various single and multiple cell scenarios. Further, it is shown that the effects of such control can be inherited without detriment to fitness.
Cite
@article{arxiv.1306.4793,
title = {Evolving Boolean Regulatory Networks with Epigenetic Control},
author = {Larry Bull},
journal= {arXiv preprint arXiv:1306.4793},
year = {2013}
}
Comments
18 pages, 10 figures. arXiv admin note: substantial text overlap with arXiv:1303.7220