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Optical imaging through diffusive, visually-opaque barriers, and around corners is an important challenge in many fields, ranging from defense to medical applications. Recently, novel techniques that combine time-of-flight (TOF)…

Optics · Physics 2023-05-12 Jeremy Boger-Lombard , Ori Katz

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

In deep tissue photoacoustic imaging the spatial resolution is inherently limited by the acoustic wavelength. We present an approach for surpassing the acoustic diffraction limit by exploiting temporal fluctuations in the sample absorption…

Optics · Physics 2017-05-31 Thomas Chaigne , Bastien Arnal , Sergey Vilov , Emmanuel Bossy , Ori Katz

The emerging technique of mid-infrared optical coherence tomography (MIR-OCT) takes advantage of the reduced scattering of MIR light in various materials and devices, enabling tomographic imaging at deeper penetration depths. Because of…

Time-of-flight (ToF) 3D imaging has a wealth of applications, from industrial inspection to movement tracking and gesture recognition. Depth information is recovered by measuring the round-trip flight time of laser pulses, which usually…

This work presents GS-DOT, a novel image reconstruction framework based on Gaussian Splatting (GS) for diffuse optical tomography (DOT). Inspired by GS for rendering applications, absorption coefficients are represented as a sparse sum of…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Jingjing Jiang

Optical coherence tomography (OCT) is a powerful and noninvasive method for retinal imaging. In this paper, we introduce a fast segmentation method based on a new variant of spectral graph theory named diffusion maps. The research is…

Computer Vision and Pattern Recognition · Computer Science 2012-10-09 Raheleh Kafieh , Hossein Rabbani , Michael D. Abramoff , Milan Sonka

From multi-photon imaging penetrating millimeters deep through scattering biological tissue, to super-resolution imaging conquering the diffraction limit, optical imaging techniques have greatly advanced in recent years. Notwithstanding, a…

Score-based diffusion models are a recently developed framework for posterior sampling in Bayesian inverse problems with a state-of-the-art performance for severely ill-posed problems by leveraging a powerful prior distribution learned from…

In this paper, we formulate the reconstruction problem in diffuse optical tomography (DOT) in a statistical setting for determining the optical parameters, scattering and absorption, from boundary photon density measurements. A special kind…

Numerical Analysis · Mathematics 2020-02-20 Thilo Strauss , Sanwar Ahmad , Taufiquar Khan

High-resolution computed tomography (CT) imaging is essential for medical diagnosis but requires increased radiation exposure, creating a critical trade-off between image quality and patient safety. While deep learning methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2025-06-16 Chunlei Li , Yilei Shi , Haoxi Hu , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

State-of-the-art time-of-flight (ToF) based 3D sensors suffer from poor lateral and depth resolutions. In this work, we introduce a novel sensor concept that provides ToF-based 3D measurements of real world objects with depth precisions up…

Optical coherence tomography (OCT) microscope (OCM) uses a high-numerical-aperture objective to achieve cellular-level lateral resolution. However, its practical imaging depth range is limited by the depth of focus (DOF). Although…

We present an imaging technique particularly suited to the detection of a target embedded in a strongly scattering medium. Classical imaging techniques based on the Born approximation fail in this kind of configuration because of multiply…

Classical Physics · Physics 2009-08-21 Alexandre Aubry , Arnaud Derode

High-numerical-aperture optical coherence tomography (OCT) enables sub-cellular imaging but faces a trade-off between lateral resolution and depth of focus. Computational refocusing can correct defocus in Fourier-domain OCT, yet its…

Optics · Physics 2026-05-22 Yue Zhu , Shuichi Makita , Naoki Fukutake , Yoshiaki Yasuno

Time of flight cameras may emerge as the 3-D sensor of choice. Today, time of flight sensors use phase-based sampling, where the phase delay between emitted and received, high-frequency signals encodes distance. In this paper, we present a…

Computer Vision and Pattern Recognition · Computer Science 2015-03-11 Achuta Kadambi , Vage Taamazyan , Suren Jayasuriya , Ramesh Raskar

Optical diffraction tomography (ODT) has emerged as a powerful label-free three-dimensional (3D) bioimaging techniques for observing living cells and thin tissue layers. We report a new reflection-mode ODT (rODT) method for imaging thick…

Diffraction tomography is a widely used inverse scattering technique for quantitative imaging of weakly scattering media. In its conventional formulation, diffraction tomography assumes monochromatic plane wave illumination. This…

Numerical Analysis · Mathematics 2026-03-11 Peter Elbau , Noemi Naujoks , Otmar Scherzer

Time-of-Flight (ToF) depth sensing camera is able to obtain depth maps at a high frame rate. However, its low resolution and sensitivity to the noise are always a concern. A popular solution is upsampling the obtained noisy low resolution…

Computer Vision and Pattern Recognition · Computer Science 2015-06-18 Wei Liu , Yijun Li , Xiaogang Chen , Jie Yang , Qiang Wu , Jingyi Yu

Optical diffraction tomography (ODT) is a tomographic technique that can be used to measure the three-dimensional (3D) refractive index distribution within living cells without the requirement of any marker. In principle, ODT can be…

Quantitative Methods · Quantitative Biology 2018-01-03 Paul Müller , Mirjam Schürmann , Chii J. Chan , Jochen Guck