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Optical coherence tomography (OCT) is a non-invasive, micrometer-scale imaging modality that has become a clinical standard in ophthalmology. By raster-scanning the retina, sequential cross-sectional image slices are acquired to generate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Stefan Ploner , Jungeun Won , Julia Schottenhamml , Jessica Girgis , Kenneth Lam , Nadia Waheed , James Fujimoto , Andreas Maier

We report on a theoretical model for image formation in full-field optical coherence tomography (FFOCT). Because the spatial incoherence of the illumination acts as a virtual confocal pinhole in FFOCT, its imaging performance is equivalent…

An ideal imaging system provides a spatial resolution that is ultimately dictated by the numerical aperture (NA) of the illumination and collection optics. In biological tissue, resolution is further affected by scattering limiting the…

In radar systems, high resolution in the Doppler dimension is important for detecting slow-moving targets as it allows for more distinct separation between these targets and clutter, or stationary objects. However, achieving sufficient…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Denisa Qosja , Kilian Barth , Simon Wagner

Recent advancements in deep learning for medical image segmentation are often limited by the scarcity of high-quality training data.While diffusion models provide a potential solution by generating synthetic images, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Jianhao Xie , Ziang Zhang , Zhenyu Weng , Yuesheng Zhu , Guibo Luo

Optical scattering presents a major obstacle to high resolution imaging in biological tissue and other turbid media. Conventional photoacoustic imaging can partially overcome this obstacle, enabling imaging of optical absorption in the…

Holography encodes the three dimensional (3D) information of a sample in the form of an intensity-only recording. However, to decode the original sample image from its hologram(s), auto-focusing and phase-recovery are needed, which are in…

Computer Vision and Pattern Recognition · Computer Science 2018-12-31 Yichen Wu , Yair Rivenson , Yibo Zhang , Zhensong Wei , Harun Gunaydin , Xing Lin , Aydogan Ozcan

Optical diffraction tomography (ODT) is an interferometric microscopy technique capable of measuring 3-D refractive index (RI) distribution of transparent samples. Multiple 2-D holograms of a sample illuminated with various angles are…

Tomography is the three-dimensional reconstruction of an object from images taken at different angles. The term classical tomography is used, when the imaging beam travels in straight lines through the object. This assumption is valid for…

Quantitative Methods · Quantitative Biology 2016-10-10 Paul Müller , Mirjam Schürmann , Jochen Guck

Discrete delta functions define the limits of attainable spatial resolution for all imaging systems. Here we construct broad, multi-dimensional discrete functions that replicate closely the action of a Dirac delta function under aperiodic…

Image and Video Processing · Electrical Eng. & Systems 2020-09-01 I. D. Svalbe , D. M. Paganin , T. C. Petersen

We introduce Doppler time-of-flight (D-ToF) rendering, an extension of ToF rendering for dynamic scenes, with applications in simulating D-ToF cameras. D-ToF cameras use high-frequency modulation of illumination and exposure, and measure…

Graphics · Computer Science 2023-10-06 Juhyeon Kim , Wojciech Jarosz , Ioannis Gkioulekas , Adithya Pediredla

Optical coherence tomography (OCT) has proven to be a powerful technique for studying tissue morphology in ophthalmology, cardiology, and endomicroscopy. Its performance is limited by the fundamental trade-off between the imaging…

Optics · Physics 2008-02-27 Keisuke Goda , Daniel R. Solli , Bahram Jalali

Ultrasound Computed Tomography (USCT) has great potential for 3D quantitative imaging of acoustic breast tissue properties. Typical devices include high-frequency transducers, which makes tomography techniques based on numerical wave…

Medical Physics · Physics 2019-08-12 N. Korta Martiartu , C. Boehm , A. Fichtner

Significance: Confocal laser scanning enables optical sectioning in fiber bundle endomicroscopy but limits the frame rate. To be able to better explore tissue morphology it is useful to stitch sequentially acquired frames into a mosaic.…

Optics · Physics 2021-07-14 Andrew D. Thrapp , Michael R. Hughes

In fluorescence diffuse optical tomography (fDOT), the reconstruction of the fluorophore concentration inside the target body is usually carried out using a normalized Born approximation model where the measured fluorescent emission data is…

Computational Physics · Physics 2015-01-05 Meghdoot Mozumder , Tanja Tarvainen , Simon Arridge , Jari P. Kaipio , Cosimo d'Andrea , Ville Kolehmainen

Three-dimensional microscopy is often limited by anisotropic spatial resolution, resulting in lower axial resolution than lateral resolution. Current State-of-The-Art (SoTA) isotropic reconstruction methods utilizing deep neural networks…

Image and Video Processing · Electrical Eng. & Systems 2023-06-22 Mingjie Pan , Yulu Gan , Fangxu Zhou , Jiaming Liu , Aimin Wang , Shanghang Zhang , Dawei Li

Tomography aims to recover a three-dimensional (3D) density map of a medium or an object. In medical imaging, it is extensively used for diagnostics via X-ray computed tomography (CT). Optical diffusion tomography is an alternative to X-ray…

Computational Physics · Physics 2020-05-26 Aviad Levis , Yoav Y. Schechner , Anthony B. Davis , Jesse Loveridge

Diffusion models (DMs) have exhibited remarkable efficacy in various image restoration tasks. However, existing approaches typically operate within the high-dimensional pixel space, resulting in high computational overhead. While methods…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Yang Zheng , Wen Li , Zhaoqiang Liu

Computational corrections of defocus and aberrations in optical coherence tomography (OCT) offers a promising approach to realize high-resolution imaging with deep imaging depth, but without additional high hardware costs. However, these…

Optics · Physics 2025-10-28 Shuichi Makita , Naoki Fukutake , Lida Zhu , Yoshiaki Yasuno

Satellites are widely used to estimate and monitor ground cover, providing critical information to address the challenges posed by climate change. High-resolution satellite images help to identify smaller features on the ground and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Jhanavi Hegde
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