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This paper presents a study on the integration of domain-specific knowledge in prompt engineering to enhance the performance of large language models (LLMs) in scientific domains. A benchmark dataset is curated to encapsulate the intricate…

Computation and Language · Computer Science 2024-04-24 Hongxuan Liu , Haoyu Yin , Zhiyao Luo , Xiaonan Wang

There is more and more evidence that machine learning can be successfully applied in materials science and related fields. However, datasets in these fields are often quite small ($\ll1000$ samples). It makes the most advanced machine…

Computational Physics · Physics 2022-02-25 Guillaume Lambard , Ekaterina Gracheva

Cancer is one of the most common diseases worldwide, posing a serious threat to human health and leading to the deaths of a large number of people. It was observed during the drug administration in chemotherapy that immune cells, cancer…

Quantitative Methods · Quantitative Biology 2020-08-20 SeyedMehdi Abtahi , Mojtaba Sharifi

The ability to perform accurate prognosis of patients is crucial for proactive clinical decision making, informed resource management and personalised care. Existing outcome prediction models suffer from a low recall of infrequent positive…

Predicting the solubility of given molecules remains crucial in the pharmaceutical industry. In this study, we revisited this extensively studied topic, leveraging the capabilities of contemporary computing resources. We employed two…

Quantitative Methods · Quantitative Biology 2024-01-08 John Ho , Zhao-Heng Yin , Colin Zhang , Nicole Guo , Yang Ha

General-purpose Large Language Models (LLMs) are frequently fine-tuned through supervised fine-tuning (SFT) to enhance performance in specific domains. Better results can be achieved by distilling the chain-of-thought of a larger model at…

Machine Learning · Computer Science 2026-03-24 Andrey Goncharov , Daniil Vyazhev , Petr Sychev , Edvard Khalafyan , Alexey Zaytsev

Since the advent of machine learning, interpretability has remained a persistent challenge, becoming increasingly urgent as generative models support high-stakes applications in drug and material discovery. Recent advances in large language…

Machine Learning · Computer Science 2025-12-10 Jaron Cohen , Alexander G. Hasson , Sara Tanovic

The recent worldwide outbreak of the novel coronavirus (COVID-19) has opened up new challenges to the research community. Artificial intelligence (AI) driven methods can be useful to predict the parameters, risks, and effects of such an…

Populations and Evolution · Quantitative Biology 2020-09-17 Ratnabali Pal , Arif Ahmed Sekh , Samarjit Kar , Dilip K. Prasad

Production Lines and Conveying Systems are the staple of modern manufacturing processes. Manufacturing efficiency is directly related to the efficiency of the means of production and conveying. Modelling in the industrial context has always…

Machine Learning · Computer Science 2025-03-04 Iyas AlTalafha , Yaprak Yalcin , Gulcihan Ozdemir

Reliable in silico molecular toxicity prediction is a cornerstone of modern drug discovery, offering a scalable alternative to experimental screening. However, the black-box nature of state-of-the-art models remains a significant barrier to…

Computational Engineering, Finance, and Science · Computer Science 2025-12-15 Kwun Sy Lee , Jiawei Chen , Fuk Sheng Ford Chung , Tianyu Zhao , Zhenyuan Chen , Debby D. Wang

Large language models (LLMs) have revolutionized the field of AI, demonstrating unprecedented capacity across various tasks. However, the inference process for LLMs comes with significant computational costs. In this paper, we propose an…

Computation and Language · Computer Science 2023-05-30 Zangwei Zheng , Xiaozhe Ren , Fuzhao Xue , Yang Luo , Xin Jiang , Yang You

Chemical representation learning has gained increasing interest due to the limited availability of supervised data in fields such as drug and materials design. This interest particularly extends to chemical language representation learning,…

Chemical Physics · Physics 2024-08-06 Jun-Hyung Park , Yeachan Kim , Mingyu Lee , Hyuntae Park , SangKeun Lee

Our work explores the utilization of deep learning, specifically leveraging the CodeBERT model, to enhance code security testing for Python applications by detecting SQL injection vulnerabilities. Unlike traditional security testing methods…

Cryptography and Security · Computer Science 2025-08-29 Guan-Yan Yang , Yi-Heng Ko , Farn Wang , Kuo-Hui Yeh , Haw-Shiang Chang , Hsueh-Yi Chen

Machine learning (ML) is revolutionising drug discovery by expediting the prediction of small molecule properties essential for developing new drugs. These properties -- including absorption, distribution, metabolism and excretion (ADME)--…

Machine Learning · Computer Science 2024-08-02 Alex G. C. de Sá , David B. Ascher

Forecasting winners in E-sports with real-time analytics has the potential to further engage audiences watching major tournament events. However, making such real-time predictions is challenging due to unpredictable variables within the…

Machine Learning · Computer Science 2024-02-27 Kittimate Chulajata , Sean Wu , Fabien Scalzo , Eun Sang Cha

Aqueous solubility (AS) is a key physiochemical property that plays a crucial role in drug discovery and material design. We report a novel unified approach to predict and infer chemical compounds with the desired AS based on simple…

Machine Learning · Computer Science 2024-09-09 Muniba Batool , Naveed Ahmed Azam , Jianshen Zhu , Kazuya Haraguchi , Liang Zhao , Tatsuya Akutsu

In response to the increasing ransomware threat, this study presents a novel detection system that integrates Convolutional Neural Networks (CNNs) and Long Short-Term Memory (LSTM) networks. By leveraging Sysmon logs, the system enables…

Cryptography and Security · Computer Science 2025-01-03 Jamil Ispahany , MD Rafiqul Islam , M. Arif Khan , MD Zahidul Islam

The article proposes a conceptual approach for evaluating the impact of engineered nanoparticles (NPs) on the functionality of small biomolecules. The developed machine learning (ML) model is based on in-silico 13C NMR spectroscopy chemical…

Other Quantitative Biology · Quantitative Biology 2026-03-23 Mariya L Ivanova , Michael Nichols , Nicola Russo , Gueorgui Mihaylov , Konstantin Nikolic

The Long Short-Term Memory (LSTM) layer is an important advancement in the field of neural networks and machine learning, allowing for effective training and impressive inference performance. LSTM-based neural networks have been…

Neural and Evolutionary Computing · Computer Science 2019-01-04 Daniel Kent , Fathi M. Salem

LSTM or Long Short Term Memory Networks is a specific type of Recurrent Neural Network (RNN) that is very effective in dealing with long sequence data and learning long term dependencies. In this work, we perform sentiment analysis on a GOP…

Computation and Language · Computer Science 2020-05-11 Karthik Gopalakrishnan , Fathi M. Salem