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Reliable whole slide imaging (WSI) hinges on image quality,yet staining artefacts, defocus, and cellular degradations are common. We present DPC-QA Net, a no-reference dual-stream network that couples wavelet-based global difference…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Qijun Yang , Boyang Wang , Hujun Yin

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

Image and Video Processing · Electrical Eng. & Systems 2023-02-23 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

Purpose: Accurate wound segmentation is essential for automated DESIGN-R scoring. However, existing models such as FUSegNet, which are trained primarily on foot ulcer datasets, often fail to generalize to wounds on other body sites.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Yun-Cheng Tsai

Accurate and fast extraction of lung volumes from computed tomography (CT) scans remains in a great demand in the clinical environment because the available methods fail to provide a generic solution due to wide anatomical variations of…

Computer Vision and Pattern Recognition · Computer Science 2016-11-15 Awais Mansoor , Ulas Bagci , Brent Foster , Ziyue Xu , Deborah Douglas , Jeffrey M. Solomon , Jayaram K. Udupa , Daniel J. Mollura

It is clinically crucial and potentially very beneficial to be able to analyze and model directly the spatial distributions of cells in histopathology whole slide images (WSI). However, most existing WSI datasets lack cell-level…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Zijiang Yang , Zhongwei Qiu , Tiancheng Lin , Hanqing Chao , Wanxing Chang , Yelin Yang , Yunshuo Zhang , Wenpei Jiao , Yixuan Shen , Wenbin Liu , Dongmei Fu , Dakai Jin , Ke Yan , Le Lu , Hui Jiang , Yun Bian

Deep learning-based diagnostic performance increases with more annotated data, but large-scale manual annotations are expensive and labour-intensive. Experts evaluate diagnostic images during clinical routine, and write their findings in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Joeran S. Bosma , Anindo Saha , Matin Hosseinzadeh , Ilse Slootweg , Maarten de Rooij , Henkjan Huisman

The quantification of biomarkers on immunohistochemistry breast cancer images is essential for defining appropriate therapy for breast cancer patients, as well as for extracting relevant information on disease prognosis. This is an arduous…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Blanca Maria Priego-Torresa , Barbara Lobato-Delgado , Lidia Atienza-Cuevas , Daniel Sanchez-Morillo

Purpose: An investigation of the challenge of annotating discrete segmentations of brain tumours in ultrasound, with a focus on the issue of aleatoric uncertainty along the tumour margin, particularly for diffuse tumours. A segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Alistair Weld , Luke Dixon , Alfie Roddan , Giulio Anichini , Sophie Camp , Stamatia Giannarou

Digital pathology has emerged as a transformative approach to tissue analysis, offering unprecedented opportunities for objective, quantitative assessment of histopathological features. However, the complexity of implementing artificial…

Quantitative Methods · Quantitative Biology 2025-09-17 Noor Shaker , Mohamed AbouZleikha , Nuha Shaker

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Delineation of cancerous regions in gigapixel whole slide images (WSIs) is a crucial diagnostic procedure in digital pathology. This process is time-consuming because of the large search space in the gigapixel WSIs, causing chances of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Hsien-Tzu Cheng , Chun-Fu Yeh , Po-Chen Kuo , Andy Wei , Keng-Chi Liu , Mong-Chi Ko , Kuan-Hua Chao , Yu-Ching Peng , Tyng-Luh Liu

Deep learning-based methods, such as the sliding window approach for cropped-image classification and heuristic aggregation for whole-slide inference, for analyzing histological patterns in high-resolution microscopy images have shown…

Image and Video Processing · Electrical Eng. & Systems 2019-12-05 Naofumi Tomita , Behnaz Abdollahi , Jason Wei , Bing Ren , Arief Suriawinata , Saeed Hassanpour

Manual annotation of medical images is a labor-intensive and time-consuming process, posing a significant bottleneck in the development and deployment of robust medical imaging AI systems. This paper introduces a novel hands-free Human-AI…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yizhe Zhang

Histopathological image segmentation is a challenging and important topic in medical imaging with tremendous potential impact in clinical practice. State of the art methods rely on hand-crafted annotations which hinder clinical translation…

The ability to quickly annotate medical imaging data plays a critical role in training deep learning frameworks for segmentation. Doing so for image volumes or video sequences is even more pressing as annotating these is particularly…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Laurent Lejeune , Raphael Sznitman

We propose a new method that employs transfer learning techniques to effectively correct sampling selection errors introduced by sparse annotations during supervised learning for automated tumor segmentation. The practicality of current…

Recent years showed a strong increase in biomedical sciences and an inherent increase in publication volume. Extraction of specific information from these sources requires highly sophisticated text mining and information extraction tools.…

Computation and Language · Computer Science 2020-04-09 Johannes Kirschnick , Philippe Thomas , Roland Roller , Leonhard Hennig

Assessing the presence of potentially malignant lymph nodes aids in estimating cancer progression, and identifying surrounding benign lymph nodes can assist in determining potential metastatic pathways for cancer. For quantitative analysis,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Litingyu Wang , Yijie Qu , Xiangde Luo , Wenjun Liao , Shichuan Zhang , Guotai Wang

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

Segmenting histology images into diagnostically relevant regions is imperative to support timely and reliable decisions by pathologists. To this end, computer-aided techniques have been proposed to delineate relevant regions in scanned…